| scholarly article | Q13442814 |
| P50 | author | Jill Suttles | Q62050079 |
| Richard Lamont | Q89232703 | ||
| P2093 | author name string | David A Scott | |
| Shuang Liang | |||
| Ravi Jotwani | |||
| Shegan Gao | |||
| Huaxin Zhou | |||
| Jonathan Brown | |||
| Huizhi Wang | |||
| P2860 | cites work | Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor | Q44639305 |
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| Loss of Jak2 selectively suppresses DC-mediated innate immune response and protects mice from lethal dose of LPS-induced septic shock | Q33541021 | ||
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| The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation. | Q33734148 | ||
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| Toll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2. | Q33771582 | ||
| Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4. | Q33901666 | ||
| Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT | Q34144743 | ||
| Stat5a/b are essential for normal lymphoid development and differentiation | Q34253065 | ||
| Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling | Q34361655 | ||
| IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6 | Q34521302 | ||
| A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis | Q35093044 | ||
| Convergence of the mammalian target of rapamycin complex 1- and glycogen synthase kinase 3-β-signaling pathways regulates the innate inflammatory response | Q35108092 | ||
| Targeting the Jak/STAT pathway for immunosuppression | Q35579377 | ||
| Jak3 and the pathogenesis of severe combined immunodeficiency | Q35818891 | ||
| How Toll-like receptors signal: what we know and what we don't know | Q36339101 | ||
| Signaling pathways downstream of pattern-recognition receptors and their cross talk | Q36747486 | ||
| Activation of an IL-6:STAT3-dependent transcriptome in pediatric-onset inflammatory bowel disease | Q36969231 | ||
| Tyrosine kinases and inflammatory signalling | Q37387459 | ||
| Treating inflammation with the Janus kinase inhibitor CP-690,550. | Q37818691 | ||
| Role of JAK3 in myogenic differentiation | Q39436709 | ||
| Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: preclinical characterization of INCB028050. | Q39719120 | ||
| Janus kinase 3 inhibitor WHI-P154 in macrophages activated by bacterial endotoxin: differential effects on the expression of iNOS, COX-2 and TNF-alpha. | Q40037647 | ||
| MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction | Q40324640 | ||
| Inhibition of the antigen-induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-P131 and WHI-P154 in a Janus kinase 3-independent manner | Q40430700 | ||
| Janus kinase 2 is involved in lipopolysaccharide-induced activation of macrophages | Q40657235 | ||
| The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells | Q40726959 | ||
| Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors | Q41466922 | ||
| Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. | Q42431545 | ||
| Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death | Q43560460 | ||
| Specific down-regulation of interleukin-12 signaling through induction of phospho-STAT4 protein degradation | Q43627746 | ||
| Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice | Q43933405 | ||
| Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide | Q44504190 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | inflammation | Q101991 |
| toll-like receptor | Q408004 | ||
| P304 | page(s) | 1164-1174 | |
| P577 | publication date | 2013-06-24 | |
| P1433 | published in | Journal of Immunology | Q3521441 |
| P1476 | title | The role of JAK-3 in regulating TLR-mediated inflammatory cytokine production in innate immune cells | |
| P478 | volume | 191 |
| Q90381442 | Aging Triggers H3K27 Trimethylation Hoarding in the Chromatin of Nothobranchius furzeri Skeletal Muscle |
| Q37748066 | Baseline JAK phosphorylation profile of peripheral blood leukocytes, studied by whole blood phosphospecific flow cytometry, is associated with 1-year treatment response in early rheumatoid arthritis |
| Q91292188 | CUL4B negatively regulates Toll-like receptor-triggered proinflammatory responses by repressing Pten transcription |
| Q48297847 | Design and Synthesis of a Highly Selective JAK3 Inhibitor for the Treatment of Rheumatoid Arthritis |
| Q35574768 | Differential immune mechanism to HIV-1 Tat variants and its regulation by AEA [corrected]. |
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| Q34361828 | Evaluation of Toll-Like receptor 2 and 4 RNA expression and the cytokine profile in postmenopausal women with metabolic syndrome |
| Q27013766 | GSK3β and the control of infectious bacterial diseases |
| Q42097093 | HIV-1 Tat-mediated induction of CCL5 in astrocytes involves NF-κB, AP-1, C/EBPα and C/EBPγ transcription factors and JAK, PI3K/Akt and p38 MAPK signaling pathways |
| Q52679480 | IL-12/23p40 overproduction by dendritic cells leads to an increased Th1 and Th17 polarization in a model of Yersinia enterocolitica-induced reactive arthritis in TNFRp55-/- mice. |
| Q51250802 | Impaired Akt Phosphorylation in Monocytes of Patients with Rheumatoid Arthritis. |
| Q35997991 | Inhibition of serum- and glucocorticoid-inducible kinase 1 enhances TLR-mediated inflammation and promotes endotoxin-driven organ failure |
| Q34841012 | Innate immune programing by endotoxin and its pathological consequences |
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| Q42778549 | JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages |
| Q46250228 | JAK3 and PI3K mediates bovine Interferon-tau stimulated gene expression in the blood neutrophils. |
| Q35507681 | Janus kinase 3 regulates renal 25-hydroxyvitamin D 1α-hydroxylase expression, calcitriol formation, and phosphate metabolism. |
| Q38805575 | Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases |
| Q91391227 | Novel Pyrimidines as Multitarget Protein Tyrosine Kinase Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis (IPF) |
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| Q28315036 | Role of Janus Kinase 3 in Predisposition to Obesity-associated Metabolic Syndrome |
| Q41108412 | Selective Inhibition of Janus Kinase 3 Has No Impact on Infarct Size or Neurobehavioral Outcomes in Permanent Ischemic Stroke in Mice |
| Q37660568 | Syk negatively regulates TLR4-mediated IFNβ and IL-10 production and promotes inflammatory responses in dendritic cells |
| Q89486269 | The JAK inhibitor ruxolitinib reduces inflammation in an ILC3-independent model of innate immune colitis |
| Q38168570 | Toll-like receptors signaling in glomerular diseases |
| Q93128856 | Transcriptional Response of White Adipose Tissue to Withdrawal of Vitamin B3 |
| Q98611601 | Transcriptomics uncovers substantial variability associated with alterations in manufacturing processes of macrophage cell therapy products |
| Q89666160 | miR-221-3p Drives the Shift of M2-Macrophages to a Pro-Inflammatory Function by Suppressing JAK3/STAT3 Activation |
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