Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome.

scientific article published on 17 March 2011

Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/AJH.2011.34
P932PMC publication ID3721747
P698PubMed publication ID21415842
P5875ResearchGate publication ID50420603

P50authorJohn D. ImigQ42333739
Md Abdul Hye KhanQ42808039
P2093author name stringJohn D Imig
Abdul Hye Khan
P2860cites workThird Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final reportQ27861020
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Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertensionQ28390972
Telmisartan but not valsartan inhibits TGF-beta-mediated accumulation of extracellular matrix via activation of PPARgammaQ28567488
Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat dietQ30482887
Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive ratsQ33742301
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activityQ33976477
HDAC Inhibition Attenuates Inflammatory, Hypertrophic, and Hypertensive Responses in Spontaneously Hypertensive RatsQ34099442
Attitudes of preclinical medical students towards caring for chronically ill and dying patients: does palliative care teaching make a difference?Q35561740
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Losartan and other angiotensin II antagonists for nephropathy in type 2 diabetes mellitus: a review of the clinical trial evidenceQ35641628
Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cellsQ35773071
Pleiotropic actions of PPAR gamma activators thiazolidinediones in cardiovascular diseasesQ35867207
ARBs and target organ protection. Exploring benefits beyond their antihypertensive effectsQ35868228
Simvastatin and tempol protect against endothelial dysfunction and renal injury in a model of obesity and hypertension.Q37174513
Telmisartan-induced inhibition of vascular cell proliferation beyond angiotensin receptor blockade and peroxisome proliferator-activated receptor-gamma activationQ37184165
Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activityQ42829351
Induction of hemeoxygenase-1 attenuates the hypertension and renal inflammation in spontaneously hypertensive ratsQ42953520
Comparison of purple carrot juice and β-carotene in a high-carbohydrate, high-fat diet-fed rat model of the metabolic syndromeQ42974751
Effect of the HMG-CoA reductase inhibitor rosuvastatin on early chronic kidney injury in obese zucker rats fed with an atherogenic dietQ43262113
Tempol or candesartan prevents high-fat diet-induced hypertension and renal damage in spontaneously hypertensive ratsQ43277441
Microalbuminuria reduction with valsartan in patients with type 2 diabetes mellitus: a blood pressure-independent effectQ44090671
Renal processing of albumin in diabetes and hypertension in rats: possible role of TGF-beta1.Q44248387
Comparison of renal morphology in the Streptozotocin and the SHR/N-cp models of diabetesQ44758853
Effects of pioglitazone on expressions of matrix metalloproteinases 2 and 9 in kidneys of diabetic ratsQ44986827
Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria.Q45038781
Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts.Q45249894
Peroxisome proliferator-activated receptor-alpha activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats.Q45915450
Suppression of experimental autoimmune uveitis by angiotensin II type 1 receptor blocker telmisartanQ46167652
Telmisartan but not valsartan increases caloric expenditure and protects against weight gain and hepatic steatosisQ46191945
Telmisartan has the strongest binding affinity to angiotensin II type 1 receptor: comparison with other angiotensin II type 1 receptor blockersQ46467059
Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathyQ46616440
Obesity and prevalent and incident CKD: the Hypertension Detection and Follow-Up ProgramQ46873807
Interactions between oxidative stress and inflammation in salt-sensitive hypertension.Q46962281
Effects of pioglitazone on increases in visceral fat accumulation and oxidative stress in spontaneously hypertensive hyperlipidemic rats fed a high-fat diet and sucrose solutionQ46965578
Effects of renin-angiotensin system blockade on the islet morphology and function in rats with long-term high-fat diet.Q53312680
Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: possible contribution of fat-derived factorsQ79326169
Telmisartan, its potential therapeutic implications in cardiometabolic disordersQ80551161
Chronic sodium hydrosulfide treatment decreases medial thickening of intramyocardial coronary arterioles, interstitial fibrosis, and ROS production in spontaneously hypertensive ratsQ80609679
P433issue7
P921main subjectmetabolic syndromeQ657193
P304page(s)816-821
P577publication date2011-03-17
P1433published inJournal of Clinical HypertensionQ15762840
P1476titleTelmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome
P478volume24

Reverse relations

cites work (P2860)
Q83663957Amlodipine enhances amelioration of vascular insulin resistance, oxidative stress, and metabolic disorders by candesartan in metabolic syndrome rats
Q26748814Angiotensin II type 1 receptor antagonists in animal models of vascular, cardiac, metabolic and renal disease
Q53148765Effect of valsartan on cardiac senescence and apoptosis in a rat model of cardiotoxicity.
Q84381511Emerging benefits of AT1 receptor antagonists with pleiotropic anti-inflammatory activity
Q90421219Impact of obesity as an independent risk factor for the development of renal injury: implications from rat models of obesity
Q26771825PPARs Link Early Life Nutritional Insults to Later Programmed Hypertension and Metabolic Syndrome
Q58691749Preclinical and Clinical Effects of RAS Inhibition with a Focus on Telmisartan
Q42116074Renoprotective effects of telmisartan after unilateral renal ablation in rats
Q60305219Telmisartan is effective to ameliorate metabolic syndrome in rat model - a preclinical report
Q38111434Telmisartan/Hydrochlorothiazide combination therapy for the treatment of hypertension: a pooled analysis in older and younger patients