Immunotherapy in glioblastoma: emerging options in precision medicine

scientific article published on 26 May 2016

Immunotherapy in glioblastoma: emerging options in precision medicine is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2217/CNS-2016-0009
P932PMC publication ID4926530
P698PubMed publication ID27225028

P2093author name stringSherise D Ferguson
Amy B Heimberger
Tiffany R Hodges
P2860cites workUpdated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working groupQ48271471
Dendritic cell vaccination combined with temozolomide retreatment: results of a phase I trial in patients with recurrent glioblastoma multiformeQ48467671
Adoptive immunotherapy in patients with recurrent malignant glioma: preliminary results of using autologous whole-tumor vaccine plus granulocyte-macrophage colony-stimulating factor and adoptive transfer of anti-CD3-activated lymphocytesQ48480362
Antigen-specific T-cell response from dendritic cell vaccination using cancer stem-like cell-associated antigensQ48564522
Treatment of recurrent glioma with intracavitary alloreactive cytotoxic T lymphocytes and interleukin-2Q48589950
A vaccine targeting mutant IDH1 induces antitumour immunityQ48649314
Autologous tumor cell vaccination combined with adoptive cellular immunotherapy in patients with grade III/IV astrocytomaQ49141356
Tumor-Educated Platelets as Liquid Biopsy in Cancer PatientsQ53288732
Stem cell marker CD133 affects clinical outcome in glioma patientsQ53507481
Reduction of end-stage malignant glioma by injection with autologous cytotoxic T lymphocytes.Q54956863
Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients.Q55471514
A pilot study of autologous cancer cell vaccination and cellular immunotherapy using anti-CD3 stimulated lymphocytes in patients with recurrent grade III/IV astrocytoma.Q55474945
Pilot study of local autologous tumor infiltrating lymphocytes for the treatment of recurrent malignant gliomas.Q55475772
Cell surface localization and density of the tumor-associated variant of the epidermal growth factor receptor, EGFRvIIIQ55478203
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survivalQ56986695
Trastuzumab-Induced Cardiomyopathy: Not as Benign as it Looks? A Retrospective StudyQ62476369
Frequent expression of a mutant epidermal growth factor receptor in multiple human tumorsQ71805186
Clinical significance of HER-2/neu oncogene amplification in primary breast cancer. The South Australian Breast Cancer Study GroupQ72234622
Isolation of cancer stem cells from adult glioblastoma multiformeQ81042698
NCI-MATCH launch highlights new trial design in precision-medicine eraQ85528297
Improved survival with vemurafenib in melanoma with BRAF V600E mutationQ24631953
Consensus on the role of human cytomegalovirus in glioblastomaQ24632103
Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in CancerQ24633070
An integrated genomic analysis of human glioblastoma multiformeQ24648860
IDH1 and IDH2 mutations in gliomasQ24648948
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activityQ24652600
Immune Checkpoint Modulators: An Emerging Antiglioma ArmamentariumQ26765459
Molecular testing in lung cancer in the era of precision medicineQ26824599
A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19Q26849476
Immunotherapy advances for glioblastomaQ26866513
Immunotherapy for primary brain tumors: no longer a matter of privilegeQ27002510
CTLA-4 and PD-1/PD-L1 blockade: new immunotherapeutic modalities with durable clinical benefit in melanoma patientsQ27692628
Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiformeQ27824801
K-ras mutations and benefit from cetuximab in advanced colorectal cancer.Q27851454
A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III studyQ27853118
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogeneQ27860693
Human cytomegalovirus infection and expression in human malignant glioma.Q44991512
Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.Q45918451
Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltrationQ46720423
Systemic T cell adoptive immunotherapy of malignant gliomasQ47910243
Establishment of interleukin 2 dependent cytotoxic T lymphocyte cell line specific for autologous brain tumor and its intracranial administration for therapy of the tumorQ48237354
Mutations of the BRAF gene in human cancerQ27860760
Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced CancerQ27860857
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastomaQ27860910
Improved Survival with Ipilimumab in Patients with Metastatic MelanomaQ27861062
Dendritic Cell-Based Immunotherapy Treatment for Glioblastoma MultiformeQ28087485
Cardiac dysfunction in the trastuzumab clinical trials experienceQ28204298
Trastuzumab-related cardiotoxicity: calling into question the concept of reversibilityQ28239961
I-SPY 2: an adaptive breast cancer trial design in the setting of neoadjuvant chemotherapyQ28244849
A Pilot Study of IL-2Rα Blockade during Lymphopenia Depletes Regulatory T-cells and Correlates with Enhanced Immunity in Patients with GlioblastomaQ28731711
Genetic basis for clinical response to CTLA-4 blockade in melanomaQ29620594
Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastomaQ30491742
Sleeping Beauty System to Redirect T-cell Specificity for Human ApplicationsQ30535187
Detection of viral pathogens in high grade gliomas from unmapped next-generation sequencing data.Q30794277
Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastomaQ33286242
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosomeQ33336718
Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: an institutional-based reviewQ33561966
Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenograftsQ33606096
Cytokine responsiveness of CD8(+) T cells is a reproducible biomarker for the clinical efficacy of dendritic cell vaccination in glioblastoma patients.Q33691858
Targeting 4-1BB costimulation to the tumor stroma with bispecific aptamer conjugates enhances the therapeutic index of tumor immunotherapyQ33887448
Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma modelQ33889603
The molecular biology of chronic myeloid leukemia.Q34079452
Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: results of the HGG-2006 phase I/II trialQ34242939
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.Q34276759
Mutational analysis reveals the origin and therapy-driven evolution of recurrent gliomaQ34391844
Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed GlioblastomaQ34488771
Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcelluloQ34666875
Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastomaQ34722415
Manufacture of Clinical-Grade CD19-Specific T Cells Stably Expressing Chimeric Antigen Receptor Using Sleeping Beauty System and Artificial Antigen Presenting CellsQ34760414
Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapyQ34764143
Major differences between tumor and normal human cell fates after exposure to chemotherapeutic monofunctional alkylatorQ34982828
EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastomaQ35145144
Evaluating many treatments and biomarkers in oncology: a new designQ35379179
Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastomaQ35741739
Patterns of care and survival for patients with glioblastoma multiforme diagnosed during 2006Q35760653
Lung cancer in the era of precision medicineQ35861107
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patientsQ35878158
Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor ActivityQ36218880
RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer DiagnosticsQ36278318
Glucocorticoid signaling: a nongenomic mechanism for T-cell immunosuppressionQ36733385
Identifying the mesenchymal molecular subtype of glioblastoma using quantitative volumetric analysis of anatomic magnetic resonance imagesQ36792763
Prioritization schema for immunotherapy clinical trials in glioblastomaQ37078999
Transforming Cancer Prevention through Precision Medicine and Immune-oncology.Q37114360
Immune response in patients with newly diagnosed glioblastoma multiforme treated with intranodal autologous tumor lysate-dendritic cell vaccination after radiation chemotherapy.Q37154132
Genomic correlates of response to CTLA-4 blockade in metastatic melanomaQ37319470
MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance.Q37331928
Intracerebral delivery of a third generation EGFRvIII-specific chimeric antigen receptor is efficacious against human glioma.Q37402375
Evaluation of tumor-derived MRI-texture features for discrimination of molecular subtypes and prediction of 12-month survival status in glioblastomaQ37490196
Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and managementQ37516733
Challenges in clinical design of immunotherapy trials for malignant gliomaQ37640613
Challenges in immunotherapy presented by the glioblastoma multiforme microenvironmentQ37970682
Vaccine therapies for patients with glioblastomaQ38243975
Current challenges in designing GBM trials for immunotherapyQ38313826
PD-1 blockade therapy in renal cell carcinoma: current studies and future promises.Q38317515
Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) TrialQ38386761
Significant association of multiple human cytomegalovirus genomic Loci with glioblastoma multiforme samplesQ38407022
Precision medicine for metastatic breast cancer--limitations and solutions.Q38551394
Immunomonitoring in glioma immunotherapy: current status and future perspectivesQ38659771
Effective immuno-targeting of the IDH1 mutation R132H in a murine model of intracranial gliomaQ38890122
Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumorsQ39089944
BLyS levels correlate with vaccine-induced antibody titers in patients with glioblastoma lymphodepleted by therapeutic temozolomideQ39434173
Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironmentQ40400501
Effects of local injection of ex vivo expanded autologous tumor-specific T lymphocytes in cases with recurrent malignant gliomas.Q40550883
T cell adoptive immunotherapy of newly diagnosed gliomasQ40619438
Epidermal growth factor receptor VIII peptide vaccination is efficacious against established intracerebral tumorsQ40630013
Adoptive immunotherapy of malignant glioma using tumor-sensitized T lymphocytesQ41491256
Exomics and immunogenics: Bridging mutational load and immune checkpoints efficacyQ41983246
Dexamethasone potentiates myeloid-derived suppressor cell function in prolonging allograft survival through nitric oxideQ42211142
Autologous T-cell therapy for cytomegalovirus as a consolidative treatment for recurrent glioblastoma.Q42220581
Comprehensive metagenomic analysis of glioblastoma reveals absence of known virus despite antiviral-like type I interferon gene responseQ42248504
Tipping a favorable CNS intratumoral immune response using immune stimulation combined with inhibition of tumor-mediated immune suppressionQ42577764
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.Q42848152
Integration of autologous dendritic cell-based immunotherapy in the primary treatment for patients with newly diagnosed glioblastoma multiforme: a pilot studyQ43166491
Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 studyQ43904522
Tumor-specific activation of an EGFR-targeting probody enhances therapeutic indexQ44705970
P433issue3
P921main subjectglioblastomaQ282142
immunotherapyQ1427096
P304page(s)175-186
P577publication date2016-05-26
P13046publication type of scholarly workreview articleQ7318358
P1433published inCNS oncologyQ26842350
P1476titleImmunotherapy in glioblastoma: emerging options in precision medicine
P478volume5

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cites work (P2860)
Q57111067Glioblastoma Treatments: An Account of Recent Industrial Developments
Q92421241Pericytes in Glioblastomas: Multifaceted Role Within Tumor Microenvironments and Potential for Therapeutic Interventions
Q90326744Responsiveness to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade in SB28 and GL261 mouse glioma models
Q48169881Synergistic inhibition of glioma cell proliferation by Withaferin A and tumor treating fields

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