Effects of antimitotic agents on tubulin-nucleotide interactions

scientific article published on November 1, 1991

Effects of antimitotic agents on tubulin-nucleotide interactions is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/0163-7258(91)90004-6
P953full work available at URLhttps://api.elsevier.com/content/article/PII:0163725891900046?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:0163725891900046?httpAccept=text/xml
P698PubMed publication ID1818332

P2093author name stringJ. J. Correia
P2860cites workDynamic instability of microtubule growthQ29547522
Allosteric proteins and cellular control systemsQ33970893
Beyond self-assembly: from microtubules to morphogenesisQ34181655
Magnesium-induced self-association of calf brain tubulin. I. StoichiometryQ35020395
Polarity of some motility-related microtubulesQ35307731
LINKED FUNCTIONS AND RECIPROCAL EFFECTS IN HEMOGLOBIN: A SECOND LOOK.Q35493170
Structural polarity of kinetochore microtubules in PtK1 cellsQ36204428
Effect of tau on the vinblastine-induced aggregation of tubulinQ36204895
Taxol binds to polymerized tubulin in vitroQ36205486
A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs).Q36205906
Isolation of Chinese hamster ovary cell mutants requiring the continuous presence of taxol for cell divisionQ36207411
Taxol-induced bundling of brain-derived microtubulesQ36211434
Interaction of vinblastine with steady-state microtubules in vitroQ48921032
Effect of guanine nucleotides on the hydrophobic interaction of tubulinQ48967624
Control of the structural fidelity of microtubules by initiation sitesQ49016810
Preparation of tubulin from brainQ49042886
Spatial separation of the two essential thiol groups and the binding site of the exchangeable GTP in brain tubulinQ49154982
GTPase activity of the tubulin-colchicine in relation with tubulin-tubulin interactionsQ49157879
Mechanism of GTP hydrolysis in tubulin polymerization: characterization of the kinetic intermediate microtubule-GDP-Pi using phosphate analogues.Q52538914
Stoichiometry of the vinblastine-induced self-association of calf brain tubulin.Q52763225
Mechanism of colchicine binding to tubulin. Tolerance of substituents in ring C' of biphenyl analogues.Q54078962
Maytansine-resistant mutants of Chinese hamster ovary cells with an alteration in alpha-tubulin.Q54448713
Spectroscopic and kinetic features of allocolchicine binding to tubulinQ57138516
Visualization of the dynamic instability of individual microtubules by dark-field microscopyQ59067947
Microtubule assembly nucleated by isolated centrosomesQ59067979
Binding of ATP to tubulinQ59081323
Maytansine inhibits nucleotide binding at the exchangeable site of tubulin.Q64958861
Polymerization of tubulin in the presence of colchicine or podophyllotoxin. Formation of a ribbon structure induced by guanylyl-5'-methylene diphosphonateQ66994217
GTP analogues interact with the tubulin exchangeable site during assembly and upon bindingQ67282186
Qualitative study of the interaction mechanism of estrogenic drugs with tubulinQ67913684
Fast disassembly of microtubules induced by Mg2+ or Ca2+Q67946939
Identification of zinc-binding sites of proteins: zinc binds to the amino-terminal region of tubulinQ67966326
Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindolineQ68183368
Effect of solution variables on the binding of vinblastine to tubulinQ68431181
Dynamic instability of sheared microtubules observed by quasi-elastic light scatteringQ68513990
Tubulin-colchicine interactions and polymerization of the complexQ68729748
Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domainQ68816801
Apparently irreversible GTP hydrolysis attends tubulin self-assemblyQ68883111
Influence of guanine nucleotides on vincristine binding in tumor cytosols and purified tubulin: evidence for an inhibitor of vincristine bindingQ68897700
Regulatory aspects of the colchicine interactions with tubulinQ68930357
Microtubules and microtubule-associated proteins from the nematode Caenorhabditis elegans: periodic cross-links connect microtubules in vitroQ36213105
Microtubule dynamics in interphase cellsQ36214474
Direct observation of steady-state microtubule dynamicsQ36214517
Phase dynamics at microtubule ends: the coexistence of microtubule length changes and treadmillingQ36216000
Temperature-dependent reversible assembly of taxol-treated microtubulesQ36217145
Interference of GTP hydrolysis in the mechanism of microtubule assembly: an experimental studyQ36253759
Tubulin bound to colchicine forms polymers different from microtubulesQ36319837
Taxol stabilizes microtubules in mouse fibroblast cellsQ36360499
Structural and functional alterations in microtubule protein from Chinese hamster ovary cell mutantsQ36368395
Dynamics of microtubules visualized by darkfield microscopy: treadmilling and dynamic instabilityQ36421940
GTP hydrolysis by tubulin occurs with water oxygen incorporation into inorganic phosphateQ36453887
The colR4 and colR15 beta-tubulin mutations in Chlamydomonas reinhardtii confer altered sensitivities to microtubule inhibitors and herbicides by enhancing microtubule stabilityQ36529609
Three Drosophila beta-tubulin sequences: a developmentally regulated isoform (beta 3), the testis-specific isoform (beta 2), and an assembly-defective mutation of the testis-specific isoform (B2t8) reveal both an ancient divergence in metazoan isotyQ36842519
Chemistry of colchicineQ37182635
Tubulin sulfhydryl groups as probes and targets for antimitotic and antimicrotubule agentsQ37182641
Nucleotide hydrolysis in cytoskeletal assemblyQ37188170
Competitive inhibition of colchicine binding to tubulin by microtubule-associated proteinsQ37310509
Common and distinct tubulin binding sites for microtubule-associated proteinsQ37400525
Molecular structure and function of microtubule-associated proteinsQ37658077
Study of strong to ultratight protein interactions using differential scanning calorimetryQ37951616
Polymorphism of tubulin assembly. In vitro formation of sheet, twisted ribbon and microtubuleQ38567705
Unstained microtubules studied by cryo-electron microscopy. Substructure, supertwist and disassemblyQ38590861
Microtubule dynamics and kinetochore function in mitosisQ39544481
Structure and utilization of tubulin isotypesQ39544501
The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazolesQ39560991
Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activityQ39750512
Molecular biology and genetics of tubulin.Q39826669
Relationship between Tubulin SH Groups and Bound Guanine NucleotidesQ40058655
Taxol: an antimitotic agent with a new mechanism of actionQ40095632
Mechanisms of assembly and disassembly of microtubulesQ40152847
Identification of a gene for α-tubulin in Aspergillus nidulansQ41062613
Role of GTP hydrolysis in microtubule polymerization: evidence for a coupled hydrolysis mechanismQ41205870
Effect of phomopsin A on the alkylation of tubulinQ41229607
A discrete repeated sequence defines a tubulin binding domain on microtubule-associated protein tau.Q41263625
Promotion of microtubule assembly in vitro by taxolQ41461193
Effect of microtubule-associated proteins on the interaction of vincristine with microtubules and tubulinQ41487157
On the surface lattice of microtubules: helix starts, protofilament number, seam, and handednessQ41501104
The microtubule-binding fragment of microtubule-associated protein-2: location of the protease-accessible site and identification of an assembly-promoting peptideQ41591267
Effects of synthetic estrogens, (R,R)-(+)-, (S,S)-(-)-, dl- and meso-hexestrol stereoisomers on microtubule assemblyQ41776548
Kinetics and mechanism of colchicine binding to tubulin: evidence for ligand-induced conformational changeQ42024971
Interaction of a new photosensitive derivative of vinblastine, NAPAVIN, with tubulin and microtubules in vitroQ42033205
Roles of colchicine rings B and C in the binding process to tubulinQ42199107
Methylenedioxy-benzopyran analogs of podophyllotoxin, a new synthetic class of antimitotic agents that inhibit tubulin polymerizationQ42214529
Interaction of tubulin with single ring analogues of colchicineQ42263463
Microtubule-associated proteins-dependent colchicine stability of acetylated cold-labile brain microtubules from the Atlantic cod, Gadus morhua.Q43107828
Turnover of tubulin and the N site GTP in chinese hamster ovary cellsQ43535354
Physical-chemical study of daunomycin-tubulin interactionsQ43570383
Instability of pleomorphic tubulin paracrystals artificially induced by Vinca alkaloids in tissue-cultured cellsQ44142083
Sulfhydryls of platelet tubulin: their role in polymerization and colchicine bindingQ44449595
Effects of magnesium on the dynamic instability of individual microtubulesQ44524810
Direct evidence for GTP and GDP-Pi intermediates in microtubule assemblyQ45040688
Inhibition of tubulin self-assembly and tubulin-colchicine GTPase activity by guanosine 5'-(gamma-fluorotriphosphate).Q45151024
Roles of ring C oxygens in the binding of colchicine to tubulinQ45174453
Interaction of vinblastine with calf brain tubulin: effects of magnesium ionsQ45287833
Kinetic analysis of tubulin exchange at microtubule ends at low vinblastine concentrations.Q45935276
Head to tail polymerization of actinQ46173625
Influence of the guanine nucleotide phosphorylation state and of Mg2+ ions on the interaction of vinzolidine/tubulin 6 S: a fluorescence quenching studyQ46667510
Energy-transfer studies of the distance between the high-affinity metal binding site and the colchicine and 8-anilino-1-naphthalenesulfonic acid binding sites on calf brain tubulinQ48100276
Absence of 7-acetyl taxol binding to unassembled brain tubulinQ48122244
A circular dichroism study of the interaction of chlorpromazine with mouse brain tubulinQ48152400
Rhizoxin binding to tubulin at the maytansine-binding siteQ48172095
19F nuclear magnetic resonance measurement of the distance between the E-site GTP and the high-affinity Mg2+ in tubulinQ48206107
GDP state of tubulin: stabilization of double ringsQ48264563
Interaction of vinblastine with calf brain tubulin: multiple equilibriaQ48289034
In vitro reconstitution of calf brain microtubules: effects of solution variablesQ48299146
The removal of the carboxy-terminal region of tubulin favors its vinblastine-induced aggregation into spiral-like structuresQ48306634
Binding to tubulin of an allocolchicine spin probe: interaction with the essential SH groups and other active sitesQ48364751
Specific affinity labelling of tubulin with bromocolchicineQ48392100
Interactions of vinblastine and maytansine with tubulinQ48409604
Magnesium-induced self-association of calf brain tubulin. II. ThermodynamicsQ48435091
Vincristine-induced self-association of calf brain tubulinQ48453303
Taxol stabilization of microtubules in vitro: dynamics of tubulin addition and loss at opposite microtubule endsQ48453363
Diethylstilbestrol induces metaphase arrest and inhibits microtubule assemblyQ48468292
Bundling of microtubules by glyceraldehyde-3-phosphate dehydrogenase and its modulation by ATP.Q48469934
Role of tubulin-SH groups in polymerization to microtubules. Functional-SH groups in tubulin for polymerizationQ48525020
Controlled proteolysis of tubulin by subtilisin: localization of the site for MAP2 interactionQ48621501
Interaction of tubulin with bifunctional colchicine analogues: an equilibrium studyQ48683296
Taxol effect on tubulin polymerization and associated guanosine 5'-triphosphate hydrolysisQ48737215
21 Reversible assembly purification of taxol-treated microtubulesQ48826419
Evidence that the tightly bound magnesium in tubulin is associated with the N-site GTP.Q48836833
Conformational states of tubulin liganded to colchicine, tropolone methyl ether, and podophyllotoxinQ48860371
Properties of colchicine binding protein from chick embryo brain. Interactions with vinca alkaloids and podophyllotoxinQ48877309
Traces of brain microtubule-associated proteins affect dynamic properties of microtubulesQ48883156
Peptides corresponding to the second repeated sequence in MAP-2 inhibit binding of microtubule-associated proteins to microtubulesQ48895149
The role of the B-ring of colchicine in the stability of the colchicine-tubulin complexQ69052247
Is microtubule assembly a biphasic process? A fluorimetric study using 4',6-diamidino-2-phenylindole as a probeQ69056712
Interaction of phomopsin A and related compounds with purified sheep brain tubulinQ69114566
Microtubule structure at 18 A resolutionQ69149439
Binding of vinblastine to stabilized microtubulesQ69374073
Inhibition of microtubule polymerization by synthetic estrogens: formation of a ribbon structureQ69399634
Photoaffinity labeling of tubulin with (2-nitro-4-azidophenyl)deacetylcolchicine: direct evidence for two colchicine binding sitesQ69415391
Cold depolymerization of microtubules to double rings: geometric stabilization of assembliesQ69415465
Actin polymerization and ATP hydrolysisQ69433184
Structure of microtubules with reduced hydration. Comparison of results from X-ray diffraction and electron microscopyQ69450399
Assembly of pure tubulin in the absence of free GTP: effect of magnesium, glycerol, ATP, and the nonhydrolyzable GTP analoguesQ69596855
The interaction of phomopsin A with bovine brain tubulinQ69635487
Identification of the cysteine residue of beta-tubulin alkylated by the antimitotic agent 2,4-dichlorobenzyl thiocyanate, facilitated by separation of the protein subunits of tubulin by hydrophobic column chromatographyQ69718409
Structural and contractile proteins. Part C. The contractile apparatus and the cytoskeletonQ69761043
Photoaffinity labeling of tubulin subunits with a photoactive analogue of vinblastineQ69780381
Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulinQ69804725
Interaction of some estrogenic drugs with tubulin. Formation of twisted ribbon structuresQ69814970
Kinetic and thermodynamic analysis of taxol-induced polymerization of purified tubulinQ69911727
GTP influences the binding of vincristine in human tumor cytosolsQ70042567
Tubulin polymerization with ATP is mediated through the exchangeable GTP siteQ70126382
Molecular motors and the cytoskeletonQ70157453
The interactions of tropolone with magnesium ions and tubulinQ70270383
Time scale of microtubule length redistributionQ70994599
Changes in the circular dichroic spectrum of colchicine associated with its binding to tubulinQ70997259
Conformational properties of microtubule protein: their relation to the self-assembly process in vitroQ71205259
CHO mutants resistant to colchicine, colcemid or griseofulvin have an altered beta-tubulinQ71235913
Evidence for two growth steps in microtubule polymerizationQ71260445
Taxol assembles tubulin in the absence of exogenous guanosine 5'-triphosphate or microtubule-associated proteinsQ72480208
The ligand- and microtubule assembly-induced GTPase activity of purified calf brain tubulinQ72507884
Dynamic properties of microtubules at steady state in the presence of taxolQ72539217
Taxol induces microtubule assembly at low temperatureQ72541188
Modulation of tubulin-nucleotide interactions by microtubule-associated proteins: polymerization with ribose-modified analogues of guanosine 5'-triphosphateQ93854981
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
P304page(s)127-147
P577publication date1991-11-01
P1433published inPharmacology & TherapeuticsQ3378596
P1476titleEffects of antimitotic agents on tubulin-nucleotide interactions
P478volume52

Reverse relations

cites work (P2860)
Q92865754Aspects of vincristine-induced neuropathy in hematologic malignancies: a systematic review
Q39258157Biotherapeutic potential and mechanisms of action of colchicine.
Q74489752Cell cycle arrest and antitumor activity of pironetin and its derivatives
Q48286483Different effects of vinblastine on the polymerization of isotypically purified tubulins from bovine brain
Q42933523Divalent cation and ionic strength effects on Vinca alkaloid-induced tubulin self-association
Q53853229Docetaxel: a new active agent in the therapy of metastatic breast cancer.
Q36811466Emerging drug treatments for solid tumours
Q74178203Energetics of vinca alkaloid interactions with tubulin
Q54157289Enhanced interaction between tubulin and microtubule‐associated protein 2 via inhibition of MAP kinase and CDC2 kinase by paclitaxel
Q35026327Interaction of a new bis-indol derivative, KAR-2 with tubulin and its antimitotic activity
Q35563289Intraperitoneal taxanes
Q40208807Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery
Q30496972Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules
Q61809116Molecular, Biological and Structural Features of V CDR-1 Rb44 Peptide, Which Targets the Microtubule Network in Melanoma Cells
Q36074388Moving the Frontiers of Cancer Chemotherapy for Solid Tumors by Changing the Scope of Drug Development
Q33957534Mutations of oncoprotein 18/stathmin identify tubulin-directed regulatory activities distinct from tubulin association
Q34336078Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization
Q40955648Paclitaxel: a unique tubulin interacting anticancer agent
Q35167010Peptides with anticancer use or potential.
Q73344439Protein-binding patterns of the antitumor antibiotic cryptophycin 52 as measured with a two-phase partitioning system
Q37793945The biological potential of flavones
Q42061827Tryprostatin A, a specific and novel inhibitor of microtubule assembly
Q28374641Vincristine revisited

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