review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/0163-7258(91)90004-6 |
P953 | full work available at URL | https://api.elsevier.com/content/article/PII:0163725891900046?httpAccept=text/plain |
https://api.elsevier.com/content/article/PII:0163725891900046?httpAccept=text/xml | ||
P698 | PubMed publication ID | 1818332 |
P2093 | author name string | J. J. Correia | |
P2860 | cites work | Dynamic instability of microtubule growth | Q29547522 |
Allosteric proteins and cellular control systems | Q33970893 | ||
Beyond self-assembly: from microtubules to morphogenesis | Q34181655 | ||
Magnesium-induced self-association of calf brain tubulin. I. Stoichiometry | Q35020395 | ||
Polarity of some motility-related microtubules | Q35307731 | ||
LINKED FUNCTIONS AND RECIPROCAL EFFECTS IN HEMOGLOBIN: A SECOND LOOK. | Q35493170 | ||
Structural polarity of kinetochore microtubules in PtK1 cells | Q36204428 | ||
Effect of tau on the vinblastine-induced aggregation of tubulin | Q36204895 | ||
Taxol binds to polymerized tubulin in vitro | Q36205486 | ||
A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs). | Q36205906 | ||
Isolation of Chinese hamster ovary cell mutants requiring the continuous presence of taxol for cell division | Q36207411 | ||
Taxol-induced bundling of brain-derived microtubules | Q36211434 | ||
Interaction of vinblastine with steady-state microtubules in vitro | Q48921032 | ||
Effect of guanine nucleotides on the hydrophobic interaction of tubulin | Q48967624 | ||
Control of the structural fidelity of microtubules by initiation sites | Q49016810 | ||
Preparation of tubulin from brain | Q49042886 | ||
Spatial separation of the two essential thiol groups and the binding site of the exchangeable GTP in brain tubulin | Q49154982 | ||
GTPase activity of the tubulin-colchicine in relation with tubulin-tubulin interactions | Q49157879 | ||
Mechanism of GTP hydrolysis in tubulin polymerization: characterization of the kinetic intermediate microtubule-GDP-Pi using phosphate analogues. | Q52538914 | ||
Stoichiometry of the vinblastine-induced self-association of calf brain tubulin. | Q52763225 | ||
Mechanism of colchicine binding to tubulin. Tolerance of substituents in ring C' of biphenyl analogues. | Q54078962 | ||
Maytansine-resistant mutants of Chinese hamster ovary cells with an alteration in alpha-tubulin. | Q54448713 | ||
Spectroscopic and kinetic features of allocolchicine binding to tubulin | Q57138516 | ||
Visualization of the dynamic instability of individual microtubules by dark-field microscopy | Q59067947 | ||
Microtubule assembly nucleated by isolated centrosomes | Q59067979 | ||
Binding of ATP to tubulin | Q59081323 | ||
Maytansine inhibits nucleotide binding at the exchangeable site of tubulin. | Q64958861 | ||
Polymerization of tubulin in the presence of colchicine or podophyllotoxin. Formation of a ribbon structure induced by guanylyl-5'-methylene diphosphonate | Q66994217 | ||
GTP analogues interact with the tubulin exchangeable site during assembly and upon binding | Q67282186 | ||
Qualitative study of the interaction mechanism of estrogenic drugs with tubulin | Q67913684 | ||
Fast disassembly of microtubules induced by Mg2+ or Ca2+ | Q67946939 | ||
Identification of zinc-binding sites of proteins: zinc binds to the amino-terminal region of tubulin | Q67966326 | ||
Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline | Q68183368 | ||
Effect of solution variables on the binding of vinblastine to tubulin | Q68431181 | ||
Dynamic instability of sheared microtubules observed by quasi-elastic light scattering | Q68513990 | ||
Tubulin-colchicine interactions and polymerization of the complex | Q68729748 | ||
Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain | Q68816801 | ||
Apparently irreversible GTP hydrolysis attends tubulin self-assembly | Q68883111 | ||
Influence of guanine nucleotides on vincristine binding in tumor cytosols and purified tubulin: evidence for an inhibitor of vincristine binding | Q68897700 | ||
Regulatory aspects of the colchicine interactions with tubulin | Q68930357 | ||
Microtubules and microtubule-associated proteins from the nematode Caenorhabditis elegans: periodic cross-links connect microtubules in vitro | Q36213105 | ||
Microtubule dynamics in interphase cells | Q36214474 | ||
Direct observation of steady-state microtubule dynamics | Q36214517 | ||
Phase dynamics at microtubule ends: the coexistence of microtubule length changes and treadmilling | Q36216000 | ||
Temperature-dependent reversible assembly of taxol-treated microtubules | Q36217145 | ||
Interference of GTP hydrolysis in the mechanism of microtubule assembly: an experimental study | Q36253759 | ||
Tubulin bound to colchicine forms polymers different from microtubules | Q36319837 | ||
Taxol stabilizes microtubules in mouse fibroblast cells | Q36360499 | ||
Structural and functional alterations in microtubule protein from Chinese hamster ovary cell mutants | Q36368395 | ||
Dynamics of microtubules visualized by darkfield microscopy: treadmilling and dynamic instability | Q36421940 | ||
GTP hydrolysis by tubulin occurs with water oxygen incorporation into inorganic phosphate | Q36453887 | ||
The colR4 and colR15 beta-tubulin mutations in Chlamydomonas reinhardtii confer altered sensitivities to microtubule inhibitors and herbicides by enhancing microtubule stability | Q36529609 | ||
Three Drosophila beta-tubulin sequences: a developmentally regulated isoform (beta 3), the testis-specific isoform (beta 2), and an assembly-defective mutation of the testis-specific isoform (B2t8) reveal both an ancient divergence in metazoan isoty | Q36842519 | ||
Chemistry of colchicine | Q37182635 | ||
Tubulin sulfhydryl groups as probes and targets for antimitotic and antimicrotubule agents | Q37182641 | ||
Nucleotide hydrolysis in cytoskeletal assembly | Q37188170 | ||
Competitive inhibition of colchicine binding to tubulin by microtubule-associated proteins | Q37310509 | ||
Common and distinct tubulin binding sites for microtubule-associated proteins | Q37400525 | ||
Molecular structure and function of microtubule-associated proteins | Q37658077 | ||
Study of strong to ultratight protein interactions using differential scanning calorimetry | Q37951616 | ||
Polymorphism of tubulin assembly. In vitro formation of sheet, twisted ribbon and microtubule | Q38567705 | ||
Unstained microtubules studied by cryo-electron microscopy. Substructure, supertwist and disassembly | Q38590861 | ||
Microtubule dynamics and kinetochore function in mitosis | Q39544481 | ||
Structure and utilization of tubulin isotypes | Q39544501 | ||
The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles | Q39560991 | ||
Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity | Q39750512 | ||
Molecular biology and genetics of tubulin. | Q39826669 | ||
Relationship between Tubulin SH Groups and Bound Guanine Nucleotides | Q40058655 | ||
Taxol: an antimitotic agent with a new mechanism of action | Q40095632 | ||
Mechanisms of assembly and disassembly of microtubules | Q40152847 | ||
Identification of a gene for α-tubulin in Aspergillus nidulans | Q41062613 | ||
Role of GTP hydrolysis in microtubule polymerization: evidence for a coupled hydrolysis mechanism | Q41205870 | ||
Effect of phomopsin A on the alkylation of tubulin | Q41229607 | ||
A discrete repeated sequence defines a tubulin binding domain on microtubule-associated protein tau. | Q41263625 | ||
Promotion of microtubule assembly in vitro by taxol | Q41461193 | ||
Effect of microtubule-associated proteins on the interaction of vincristine with microtubules and tubulin | Q41487157 | ||
On the surface lattice of microtubules: helix starts, protofilament number, seam, and handedness | Q41501104 | ||
The microtubule-binding fragment of microtubule-associated protein-2: location of the protease-accessible site and identification of an assembly-promoting peptide | Q41591267 | ||
Effects of synthetic estrogens, (R,R)-(+)-, (S,S)-(-)-, dl- and meso-hexestrol stereoisomers on microtubule assembly | Q41776548 | ||
Kinetics and mechanism of colchicine binding to tubulin: evidence for ligand-induced conformational change | Q42024971 | ||
Interaction of a new photosensitive derivative of vinblastine, NAPAVIN, with tubulin and microtubules in vitro | Q42033205 | ||
Roles of colchicine rings B and C in the binding process to tubulin | Q42199107 | ||
Methylenedioxy-benzopyran analogs of podophyllotoxin, a new synthetic class of antimitotic agents that inhibit tubulin polymerization | Q42214529 | ||
Interaction of tubulin with single ring analogues of colchicine | Q42263463 | ||
Microtubule-associated proteins-dependent colchicine stability of acetylated cold-labile brain microtubules from the Atlantic cod, Gadus morhua. | Q43107828 | ||
Turnover of tubulin and the N site GTP in chinese hamster ovary cells | Q43535354 | ||
Physical-chemical study of daunomycin-tubulin interactions | Q43570383 | ||
Instability of pleomorphic tubulin paracrystals artificially induced by Vinca alkaloids in tissue-cultured cells | Q44142083 | ||
Sulfhydryls of platelet tubulin: their role in polymerization and colchicine binding | Q44449595 | ||
Effects of magnesium on the dynamic instability of individual microtubules | Q44524810 | ||
Direct evidence for GTP and GDP-Pi intermediates in microtubule assembly | Q45040688 | ||
Inhibition of tubulin self-assembly and tubulin-colchicine GTPase activity by guanosine 5'-(gamma-fluorotriphosphate). | Q45151024 | ||
Roles of ring C oxygens in the binding of colchicine to tubulin | Q45174453 | ||
Interaction of vinblastine with calf brain tubulin: effects of magnesium ions | Q45287833 | ||
Kinetic analysis of tubulin exchange at microtubule ends at low vinblastine concentrations. | Q45935276 | ||
Head to tail polymerization of actin | Q46173625 | ||
Influence of the guanine nucleotide phosphorylation state and of Mg2+ ions on the interaction of vinzolidine/tubulin 6 S: a fluorescence quenching study | Q46667510 | ||
Energy-transfer studies of the distance between the high-affinity metal binding site and the colchicine and 8-anilino-1-naphthalenesulfonic acid binding sites on calf brain tubulin | Q48100276 | ||
Absence of 7-acetyl taxol binding to unassembled brain tubulin | Q48122244 | ||
A circular dichroism study of the interaction of chlorpromazine with mouse brain tubulin | Q48152400 | ||
Rhizoxin binding to tubulin at the maytansine-binding site | Q48172095 | ||
19F nuclear magnetic resonance measurement of the distance between the E-site GTP and the high-affinity Mg2+ in tubulin | Q48206107 | ||
GDP state of tubulin: stabilization of double rings | Q48264563 | ||
Interaction of vinblastine with calf brain tubulin: multiple equilibria | Q48289034 | ||
In vitro reconstitution of calf brain microtubules: effects of solution variables | Q48299146 | ||
The removal of the carboxy-terminal region of tubulin favors its vinblastine-induced aggregation into spiral-like structures | Q48306634 | ||
Binding to tubulin of an allocolchicine spin probe: interaction with the essential SH groups and other active sites | Q48364751 | ||
Specific affinity labelling of tubulin with bromocolchicine | Q48392100 | ||
Interactions of vinblastine and maytansine with tubulin | Q48409604 | ||
Magnesium-induced self-association of calf brain tubulin. II. Thermodynamics | Q48435091 | ||
Vincristine-induced self-association of calf brain tubulin | Q48453303 | ||
Taxol stabilization of microtubules in vitro: dynamics of tubulin addition and loss at opposite microtubule ends | Q48453363 | ||
Diethylstilbestrol induces metaphase arrest and inhibits microtubule assembly | Q48468292 | ||
Bundling of microtubules by glyceraldehyde-3-phosphate dehydrogenase and its modulation by ATP. | Q48469934 | ||
Role of tubulin-SH groups in polymerization to microtubules. Functional-SH groups in tubulin for polymerization | Q48525020 | ||
Controlled proteolysis of tubulin by subtilisin: localization of the site for MAP2 interaction | Q48621501 | ||
Interaction of tubulin with bifunctional colchicine analogues: an equilibrium study | Q48683296 | ||
Taxol effect on tubulin polymerization and associated guanosine 5'-triphosphate hydrolysis | Q48737215 | ||
21 Reversible assembly purification of taxol-treated microtubules | Q48826419 | ||
Evidence that the tightly bound magnesium in tubulin is associated with the N-site GTP. | Q48836833 | ||
Conformational states of tubulin liganded to colchicine, tropolone methyl ether, and podophyllotoxin | Q48860371 | ||
Properties of colchicine binding protein from chick embryo brain. Interactions with vinca alkaloids and podophyllotoxin | Q48877309 | ||
Traces of brain microtubule-associated proteins affect dynamic properties of microtubules | Q48883156 | ||
Peptides corresponding to the second repeated sequence in MAP-2 inhibit binding of microtubule-associated proteins to microtubules | Q48895149 | ||
The role of the B-ring of colchicine in the stability of the colchicine-tubulin complex | Q69052247 | ||
Is microtubule assembly a biphasic process? A fluorimetric study using 4',6-diamidino-2-phenylindole as a probe | Q69056712 | ||
Interaction of phomopsin A and related compounds with purified sheep brain tubulin | Q69114566 | ||
Microtubule structure at 18 A resolution | Q69149439 | ||
Binding of vinblastine to stabilized microtubules | Q69374073 | ||
Inhibition of microtubule polymerization by synthetic estrogens: formation of a ribbon structure | Q69399634 | ||
Photoaffinity labeling of tubulin with (2-nitro-4-azidophenyl)deacetylcolchicine: direct evidence for two colchicine binding sites | Q69415391 | ||
Cold depolymerization of microtubules to double rings: geometric stabilization of assemblies | Q69415465 | ||
Actin polymerization and ATP hydrolysis | Q69433184 | ||
Structure of microtubules with reduced hydration. Comparison of results from X-ray diffraction and electron microscopy | Q69450399 | ||
Assembly of pure tubulin in the absence of free GTP: effect of magnesium, glycerol, ATP, and the nonhydrolyzable GTP analogues | Q69596855 | ||
The interaction of phomopsin A with bovine brain tubulin | Q69635487 | ||
Identification of the cysteine residue of beta-tubulin alkylated by the antimitotic agent 2,4-dichlorobenzyl thiocyanate, facilitated by separation of the protein subunits of tubulin by hydrophobic column chromatography | Q69718409 | ||
Structural and contractile proteins. Part C. The contractile apparatus and the cytoskeleton | Q69761043 | ||
Photoaffinity labeling of tubulin subunits with a photoactive analogue of vinblastine | Q69780381 | ||
Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin | Q69804725 | ||
Interaction of some estrogenic drugs with tubulin. Formation of twisted ribbon structures | Q69814970 | ||
Kinetic and thermodynamic analysis of taxol-induced polymerization of purified tubulin | Q69911727 | ||
GTP influences the binding of vincristine in human tumor cytosols | Q70042567 | ||
Tubulin polymerization with ATP is mediated through the exchangeable GTP site | Q70126382 | ||
Molecular motors and the cytoskeleton | Q70157453 | ||
The interactions of tropolone with magnesium ions and tubulin | Q70270383 | ||
Time scale of microtubule length redistribution | Q70994599 | ||
Changes in the circular dichroic spectrum of colchicine associated with its binding to tubulin | Q70997259 | ||
Conformational properties of microtubule protein: their relation to the self-assembly process in vitro | Q71205259 | ||
CHO mutants resistant to colchicine, colcemid or griseofulvin have an altered beta-tubulin | Q71235913 | ||
Evidence for two growth steps in microtubule polymerization | Q71260445 | ||
Taxol assembles tubulin in the absence of exogenous guanosine 5'-triphosphate or microtubule-associated proteins | Q72480208 | ||
The ligand- and microtubule assembly-induced GTPase activity of purified calf brain tubulin | Q72507884 | ||
Dynamic properties of microtubules at steady state in the presence of taxol | Q72539217 | ||
Taxol induces microtubule assembly at low temperature | Q72541188 | ||
Modulation of tubulin-nucleotide interactions by microtubule-associated proteins: polymerization with ribose-modified analogues of guanosine 5'-triphosphate | Q93854981 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | pharmacology | Q128406 |
P304 | page(s) | 127-147 | |
P577 | publication date | 1991-11-01 | |
P1433 | published in | Pharmacology & Therapeutics | Q3378596 |
P1476 | title | Effects of antimitotic agents on tubulin-nucleotide interactions | |
P478 | volume | 52 |
Q92865754 | Aspects of vincristine-induced neuropathy in hematologic malignancies: a systematic review |
Q39258157 | Biotherapeutic potential and mechanisms of action of colchicine. |
Q74489752 | Cell cycle arrest and antitumor activity of pironetin and its derivatives |
Q48286483 | Different effects of vinblastine on the polymerization of isotypically purified tubulins from bovine brain |
Q42933523 | Divalent cation and ionic strength effects on Vinca alkaloid-induced tubulin self-association |
Q53853229 | Docetaxel: a new active agent in the therapy of metastatic breast cancer. |
Q36811466 | Emerging drug treatments for solid tumours |
Q74178203 | Energetics of vinca alkaloid interactions with tubulin |
Q54157289 | Enhanced interaction between tubulin and microtubule‐associated protein 2 via inhibition of MAP kinase and CDC2 kinase by paclitaxel |
Q35026327 | Interaction of a new bis-indol derivative, KAR-2 with tubulin and its antimitotic activity |
Q35563289 | Intraperitoneal taxanes |
Q40208807 | Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery |
Q30496972 | Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules |
Q61809116 | Molecular, Biological and Structural Features of V CDR-1 Rb44 Peptide, Which Targets the Microtubule Network in Melanoma Cells |
Q36074388 | Moving the Frontiers of Cancer Chemotherapy for Solid Tumors by Changing the Scope of Drug Development |
Q33957534 | Mutations of oncoprotein 18/stathmin identify tubulin-directed regulatory activities distinct from tubulin association |
Q34336078 | Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization |
Q40955648 | Paclitaxel: a unique tubulin interacting anticancer agent |
Q35167010 | Peptides with anticancer use or potential. |
Q73344439 | Protein-binding patterns of the antitumor antibiotic cryptophycin 52 as measured with a two-phase partitioning system |
Q37793945 | The biological potential of flavones |
Q42061827 | Tryprostatin A, a specific and novel inhibitor of microtubule assembly |
Q28374641 | Vincristine revisited |
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