Platelet activating factor as a mediator and therapeutic approach in bronchial asthma

scientific article published on 12 January 2008

Platelet activating factor as a mediator and therapeutic approach in bronchial asthma is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S10753-007-9056-9
P698PubMed publication ID18193345

P50authorBarbara RogalaQ86841382
Alicja Kasperska-ZającQ89308720
Zenon BrzozaQ96062855
P2860cites workPlatelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipaseQ24562119
Enhancement of leukotriene B4 release in stimulated asthmatic neutrophils by platelet activating factorQ28379398
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Platelet-activating factor causes ventilation-perfusion mismatch in humansQ34119627
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Participation of the cysteinyl leukotrienes in the acute bronchoconstrictor response to inhaled platelet activating factor in manQ41142725
Priming effect of platelet activating factor on leukotriene C4 from stimulated eosinophils of asthmatic patientsQ41211488
Platelet activating factor: effects on bronchomotor tone and bronchial responsiveness in human beings.Q41299868
Effect of platelet activating factor (PAF) on the migration of human lymphocytesQ41832882
The effect of platelet-activating factor on the generation of superoxide anion in human eosinophils and neutrophilsQ41947992
No increase in plasma histamine during PAF-induced airway obstruction in allergic asthmaticsQ42506856
Increased plasma level of platelet-activating factor (PAF) and decreased serum PAF acetylhydrolase (PAFAH) activity in adults with bronchial asthma.Q42553679
Platelet-activating factor in bronchoalveolar lavage fluid from asthmatic subjectsQ44212769
Inhibitory effects of the new PAF acether antagonist WEB-2086 on pharmacologic changes induced by PAF inhalation in human beingsQ44619246
The evidence of platelet activation in bronchial asthmaQ44665675
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Platelet activating factor does not cause a reproducible increase in bronchial responsiveness in normal man.Q45003202
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PAF responsiveness in Japanese subjects with plasma PAF acetylhydrolase deficiencyQ48000951
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Increased levels of blood platelet-activating factor in bronchial asthmatic patients with active symptoms.Q51597258
Eosinophil recruitment into guinea pig lungs after PAF-acether and allergen administration. Modulation by prostacyclin, platelet depletion, and selective antagonists.Q52491574
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Bronchoconstriction and eosinophil recruitment in guinea pig lungs after platelet activating factor administration.Q53976935
Effect of a platelet-activating factor (PAF) antagonist, SR 27417A, on PAF-induced gas exchange abnormalities in mild asthma.Q54135393
Salbutamol inhibits pulmonary effects of platelet activating factor in man.Q54171130
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Bronchoconstriction induced by intratracheal administration of platelet-activating factor (PAF-acether) in baboonsQ54527263
Induction of IL-4 by platelet-activating factorQ60499029
Platelet-activating factor enhances interleukin-6 production by alveolar macrophagesQ67506279
Effect of SR 27417 on oedema formation induced in rabbit skin by platelet-activating factor or antigenQ67554476
The effect of WEB 2086 on PAF-induced eosinophil chemotaxis and LTC4 production from eosinophilsQ67596956
Basophil histamine release by platelet-activating factor in aspirin-sensitive subjects with asthmaQ67674678
Platelet-activating factor does not induce bronchial hyperreactivity in nonasthmatic subjectsQ67990113
Enhanced production of platelet activating factor by peripheral granulocytes from children with asthmaQ68030664
Platelet activating factor (PAF) is a potent stimulator of porcine tracheal fluid secretion in vitroQ68535454
Histamine release from human leukocytes by platelet-activating factorQ69021888
Platelet-activating factor (PAF-acether) induced leukotriene C4 formation and luminol dependent chemiluminescence by human eosinophilsQ69649642
Effects of inhaled platelet activating factor on pulmonary function and bronchial responsiveness in manQ69883641
The release of platelet-activating factor into plasma during allergen-induced bronchoconstrictionQ70119869
Effects of PAF antagonist, BN52021, on the PAF-, methacholine-, and allergen-induced bronchoconstriction in asthmatic childrenQ70128019
Occupancy of platelet receptors for platelet-activating factor in asthmatic patients during an allergen-induced bronchoconstrictive reactionQ70482614
Inhibition of platelet-activating factor-induced bronchoconstriction by the leukotriene D4 receptor antagonist ICI 204,219Q70530056
Effect of the platelet-activating factor antagonist UK-74,505 on the early and late response to allergenQ70530101
Increased plasma platelet-activating factor in children with acute asthmatic attacks and decreased in vivo and in vitro production of platelet-activating factor after immunotherapyQ70568778
Release of PAF-acether from human blood monocytesQ70575047
PAF-acether-induced plasma exudation in rat skin is independent of platelets and neutrophilsQ70810376
Platelet-activating factor: a possible mediator of the dual response to allergen?Q71271374
Acute bronchial obstruction following inhalation of PAF in asthmatic and normal subjects: comparison with methacholineQ71605121
Effects of lipoxin A4 on chemotaxis and degranulation of human eosinophils stimulated by platelet-activating factor and N-formyl-L-methionyl-L-leucyl-L-phenylalanineQ72075181
Effect of a novel potent platelet-activating factor antagonist, modipafant, in clinical asthmaQ72204971
Effect of cetirizine, a potent H1 antagonist, on platelet activating factor induced bronchoconstriction in asthmaQ72231521
The effect of the orally active platelet-activating factor antagonist WEB 2086 in the treatment of asthmaQ72398982
Functional platelet-activating factor receptors are expressed by monocytes and granulocytes but not by resting or activated T and B lymphocytes from normal individuals or patients with asthmaQ72526941
Allergen exposure in acute asthma causes the release of platelet-activating factor (PAF) as demonstrated by the desensitization of platelets to PAFQ72626938
Short-term and long-term role of platelet activating factor as a mediator of in vivo platelet aggregationQ72885839
Platelet-activating factor-induced human eosinophil transendothelial migration: evidence for a dynamic role of the endotheliumQ72940249
Gas exchange response to a PAF receptor antagonist, SR 27417A, in acute asthma: a pilot studyQ73136760
Anti-inflammatory actions of lipoxin A(4) stable analogs are demonstrable in human whole blood: modulation of leukocyte adhesion molecules and inhibition of neutrophil-endothelial interactionsQ73254109
Recombinant human platelet-activating factor-acetylhydrolase inhibits airway inflammation and hyperreactivity in mouse asthma modelQ73520608
Effects of a potent platelet-activating factor antagonist, SR27417A, on allergen-induced asthmatic responsesQ73528566
Inhibition of PAF-induced gas exchange defects by beta-adrenergic agonists in mild asthma is not due to bronchodilationQ73528570
Characterization of platelet-activating factor acetylhydrolase in human bronchoalveolar lavageQ73528655
PAF-induced eosinophil chemotaxis increases during an asthmatic attack and is inhibited by prednisolone in vivo and in vitroQ73614770
Comparison of platelet-activating factor receptor mRNA levels in peripheral blood eosinophils from normal subjects and atopic asthmatic patientsQ73863415
Effect of recombinant human platelet-activating factor-acetylhydrolase on allergen-induced asthmatic responsesQ74139228
Plasma platelet-activating factor acetylhydrolase deficiency in Japanese patients with asthmaQ74529450
The effects of 5-lipoxygenase inhibition by zileuton on platelet-activating-factor-induced pulmonary abnormalities in mild asthmaQ74593222
Inflammatory mediators of asthma: an updateQ77710217
Evidence for an association between plasma platelet-activating factor acetylhydrolase deficiency and increased risk of childhood atopic asthmaQ77826813
Platelet-activating factor increases the expression of metalloproteinase-9 in human bronchial epithelial cellsQ78048304
P433issue2
P921main subjectasthmaQ35869
P304page(s)112-120
P577publication date2008-01-12
P1433published inInflammationQ2560341
P1476titlePlatelet activating factor as a mediator and therapeutic approach in bronchial asthma
P478volume31

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cites work (P2860)
Q34797862A Novel Platelet-Activating Factor Receptor Antagonist Inhibits Choroidal Neovascularization and Subretinal Fibrosis
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Q34020321GM2 activator protein inhibits platelet activating factor signaling in rats
Q58801775Hydroxysafflor Yellow A Suppresses Platelet Activating Factor-Induced Activation of Human Small Airway Epithelial Cells
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