Visualizing the Bohr effect in hemoglobin: neutron structure of equine cyanomethemoglobin in the R state and comparison with human deoxyhemoglobin in the T state

scientific article published on 28 June 2016

Visualizing the Bohr effect in hemoglobin: neutron structure of equine cyanomethemoglobin in the R state and comparison with human deoxyhemoglobin in the T state is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1107/S2059798316009049
P932PMC publication ID4932920
P698PubMed publication ID27377386

P50authorPaul LanganQ44745418
Andrey KovalevskyQ47503013
P2093author name stringB Leif Hanson
S Zoë Fisher
Timothy C Mueser
Steven Dajnowicz
Sean Seaver
P2860cites workInterface sliding as illustrated by the multiple quaternary structures of liganded hemoglobinQ27628874
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Direct determination of protonation states of histidine residues in a 2 A neutron structure of deoxy-human normal adult hemoglobin and implications for the Bohr effectQ27660241
The structure of horse methaemoglobin at 2.0 Å resolutionQ27729076
Coot: model-building tools for molecular graphicsQ27860505
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Assessment of roles of surface histidyl residues in the molecular basis of the Bohr effect and of beta 143 histidine in the binding of 2,3-bisphosphoglycerate in human normal adult hemoglobinQ28610110
Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*Q29615452
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Locating active-site hydrogen atoms in D-xylose isomerase: time-of-flight neutron diffractionQ33995949
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1.25 A resolution crystal structures of human haemoglobin in the oxy, deoxy and carbonmonoxy forms.Q34536745
The structure--function relationship of hemoglobin in solution at atomic resolutionQ35685655
Evolution of vertebrate haemoglobins: Histidine side chains, specific buffer value and Bohr effectQ36397730
Protein structures by spallation neutron crystallography.Q36672477
Neutron crystallography: opportunities, challenges, and limitationsQ36982392
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Tetramer-dimer dissociation in homoglobin and the Bohr effectQ39113308
X-ray diffraction and solution studies of specifically carbamylated human hemoglobin A. Evidence for the location of a proton- and oxygen-linked chloride binding site at valine 1 alphaQ39282543
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pK values of the ionizable groups of proteinsQ43043653
Hydrogen exchange rate of tyrosine hydroxyl groups in proteins as studied by the deuterium isotope effect on C(zeta) chemical shiftsQ43232136
Measurement of structural and free energy changes in hemoglobin by hydrogen exchange methodsQ43772735
Hemoglobin Bohr effects: atomic origin of the histidine residue contributions.Q51141921
Contribution of surface histidyl residues in the alpha-chain to the Bohr effect of human normal adult hemoglobin: roles of global electrostatic effects.Q54564326
Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of AllosteryQ59054576
Identification of Residues responsible for the Alkaline Bohr Effect in HaemoglobinQ59072005
Rapid molecular characterization of mutations leading to unstable hemoglobin beta-chain variantsQ67571368
The characterization of hemoglobin Manitoba or alpha (2)102(G9)Ser----Arg beta 2 and hemoglobin Contaldo or alpha (2)103(G10)His----Arg beta 2 by high performance liquid chromatographyQ70815039
Changes in pKa values of individual histidine residues of human hemoglobin upon reaction with carbon monoxideQ71289843
Identification of residues contributing to the Bohr effect of human haemoglobinQ71306215
Studies on the function of abnormal hemoglobins I. An improved method for automatic measurement of the oxygen equilibrium curve of hemoglobinQ71546412
Isotope effects in peptide group hydrogen exchangeQ72589792
Hb Schlierbach or beta108(G10)Asn-->Ile: a new variant with low oxygen affinity detected in a Swiss familyQ74614459
Hematological and molecular characteristics of Hb Sarrebourg [beta131(H9)Gln-->Arg (CAG-->CGG)] found in a Spanish familyQ80283121
P433issuePt 7
P921main subjectvisualizationQ451553
P304page(s)892-903
P577publication date2016-06-28
P1433published inActa crystallographica. Section D, Structural biologyQ27727181
P1476titleVisualizing the Bohr effect in hemoglobin: neutron structure of equine cyanomethemoglobin in the R state and comparison with human deoxyhemoglobin in the T state
P478volume72

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cites work (P2860)
Q42379015Direct visualization of critical hydrogen atoms in a pyridoxal 5'-phosphate enzyme
Q37673023Fifteen years of the Protein Crystallography Station: the coming of age of macromolecular neutron crystallography.

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