Pasireotide (SOM230) is effective for the treatment of pancreatic neuroendocrine tumors (PNETs) in a multiple endocrine neoplasia type 1 (MEN1) conditional knockout mouse model.

scientific article published on 24 October 2012

Pasireotide (SOM230) is effective for the treatment of pancreatic neuroendocrine tumors (PNETs) in a multiple endocrine neoplasia type 1 (MEN1) conditional knockout mouse model. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.SURG.2012.08.021
P932PMC publication ID3732168
P698PubMed publication ID23102680
P5875ResearchGate publication ID232719189

P50authorSteven LibuttiQ7614982
Thomas J QuinnQ45310205
P2093author name stringWade Koba
David T Hughes
Ziqiang Yuan
Rula Geha
Herbert A Schmid
Asha Adem
Eugene Fine
Chakravarthy Vrikshajanani
P2860cites workSomatostatin receptors 2 and 5 are the major somatostatin receptors in insulinomas: an in vivo and in vitro studyQ79260198
Medical treatment of benign insulinoma using octreotide LAR: a case reportQ79379722
Somatostatin receptor subtype 5 (SSTR5) mRNA expression is related to histopathological features of cell proliferation in insulinomasQ83118235
Neuroendocrine tumors of the pancreasQ83762285
Clinical pathology of endocrine tumors of the pancreas. Analysis of autopsy casesQ28290384
Somatostatin analogs - from new molecules to new applicationsQ35938751
Diazoxide treatment for insulinoma: a national UK surveyQ36728183
Well-differentiated pancreatic tumor/carcinoma: insulinomaQ36741120
One hundred years after "carcinoid": epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United StatesQ37195528
Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.Q37429020
Multiple endocrine neoplasia type 1: clinical manifestations and managementQ37643633
Clinical review 72: diagnosis and management of functioning islet cell tumorsQ40456829
Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell lineQ42848672
Pasireotide (SOM230) demonstrates efficacy and safety in patients with acromegaly: a randomized, multicenter, phase II trialQ43089850
A single-dose comparison of the acute effects between the new somatostatin analog SOM230 and octreotide in acromegalic patientsQ44757106
SMS 201–995: A very potent and selective octapeptide analogue of somatostatin with prolonged actionQ48897339
Pasireotide, an IGF-I action inhibitor, prevents growth hormone and estradiol-induced mammary hyperplasia.Q51539178
Pancreatic endocrine tumorsQ57794113
SOM230, A New Somatostatin Analogue, Is Highly Effective in the Therapy of Growth Hormone/Prolactin-Secreting Pituitary AdenomasQ59122469
Diazoxide in the management of patients with insulinomaQ70147196
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectpasireotideQ3896970
knockout mouseQ1364740
multiple endocrine neoplasiaQ1553018
multiple endocrine neoplasia type 1Q3347154
pasireotide diaspartateQ21547171
P304page(s)1068-1077
P577publication date2012-10-24
P1433published inSurgeryQ15731526
P1476titlePasireotide (SOM230) is effective for the treatment of pancreatic neuroendocrine tumors (PNETs) in a multiple endocrine neoplasia type 1 (MEN1) conditional knockout mouse model
P478volume152