review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Birthe Fahrenkrog | Q41629404 |
Ueli Aebi | Q14594735 | ||
Roderick Lim | Q42598489 | ||
P2860 | cites work | Cryo-electron tomography provides novel insights into nuclear pore architecture: implications for nucleocytoplasmic transport | Q41629388 |
Transport between the cell nucleus and the cytoplasm | Q22065411 | ||
Nuclear envelope permeability | Q22122423 | ||
Proteomic analysis of the mammalian nuclear pore complex | Q24305242 | ||
GLFG and FxFG nucleoporins bind to overlapping sites on importin-beta | Q24310348 | ||
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex | Q24316128 | ||
Disorder in the nuclear pore complex: the FG repeat regions of nucleoporins are natively unfolded | Q24554044 | ||
Identification of different roles for RanGDP and RanGTP in nuclear protein import | Q24561933 | ||
Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import | Q24652021 | ||
Signals and structural features involved in integral membrane protein targeting to the inner nuclear membrane | Q24672562 | ||
Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex | Q24676068 | ||
The yeast nuclear pore complex: composition, architecture, and transport mechanism | Q24680784 | ||
A large particle associated with the perimeter of the nuclear pore complex | Q24681457 | ||
Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking | Q27625995 | ||
Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1 | Q27638140 | ||
Structural basis for the interaction between NTF2 and nucleoporin FxFG repeats | Q27639170 | ||
The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98 | Q27639518 | ||
Structural basis for the interaction between the Tap/NXF1 UBA domain and FG nucleoporins at 1A resolution | Q27640483 | ||
Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN | Q27643706 | ||
Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding | Q27644208 | ||
Molecular characterization of the Ran-binding zinc finger domain of Nup153 | Q27644396 | ||
Minimal nuclear pore complexes define FG repeat domains essential for transport | Q27931250 | ||
Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex | Q27931590 | ||
Molecular architecture of the yeast nuclear pore complex: localization of Nsp1p subcomplexes | Q27933725 | ||
Binding dynamics of structural nucleoporins govern nuclear pore complex permeability and may mediate channel gating | Q27935153 | ||
Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. | Q27938407 | ||
Yeast nuclear pore complexes have a cytoplasmic ring and internal filaments. | Q27939927 | ||
The N-terminal domain of Nup159 forms a beta-propeller that functions in mRNA export by tethering the helicase Dbp5 to the nuclear pore | Q27939942 | ||
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins | Q28131733 | ||
Intrinsically disordered protein | Q28191444 | ||
Nup214-Nup88 nucleoporin subcomplex is required for CRM1-mediated 60 S preribosomal nuclear export | Q28238313 | ||
Isolation of a protein that is essential for the first step of nuclear protein import | Q28243173 | ||
Entropic elasticity of lambda-phage DNA | Q28247727 | ||
Polymer brushes | Q28248200 | ||
G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214 | Q28504583 | ||
The crystal structure of mouse Nup35 reveals atypical RNP motifs and novel homodimerization of the RRM domain | Q28506997 | ||
Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins | Q28573887 | ||
Peering through the pore: nuclear pore complex structure, assembly, and function | Q28609626 | ||
The Saccharomyces cerevisiae nucleoporin Nup2p is a natively unfolded protein | Q28909274 | ||
Intrinsically unstructured proteins | Q29614784 | ||
Transport into and out of the nucleus | Q29615611 | ||
Three-dimensional architecture of the isolated yeast nuclear pore complex: functional and evolutionary implications | Q29616786 | ||
Molecular mechanism of the nuclear protein import cycle | Q29617058 | ||
Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle | Q29619289 | ||
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus | Q29620192 | ||
Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor | Q29620193 | ||
Architecture and design of the nuclear pore complex | Q29622853 | ||
Nuclear transport of single molecules: dwell times at the nuclear pore complex. | Q41873308 | ||
Significant proportions of nuclear transport proteins with reduced intracellular mobilities resolved by fluorescence correlation spectroscopy | Q41958794 | ||
Evidence for Ca2+- and ATP-sensitive peripheral channels in nuclear pore complexes | Q43726397 | ||
Passive transport of macromolecules through Xenopus laevis nuclear envelope | Q44729129 | ||
Rapid evolution exposes the boundaries of domain structure and function in natively unfolded FG nucleoporins | Q46062002 | ||
AFM and SFG studies of pHEMA-based hydrogel contact lens surfaces in saline solution: adhesion, friction, and the presence of non-crosslinked polymer chains at the surface | Q46073323 | ||
Friction studies of hydrogel contact lenses using AFM: non-crosslinked polymers of low friction at the surface | Q46462321 | ||
Structural basis for the high-affinity binding of nucleoporin Nup1p to the Saccharomyces cerevisiae importin-beta homologue, Kap95p | Q46476120 | ||
Nucleoporin domain topology is linked to the transport status of the nuclear pore complex | Q46620275 | ||
Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p | Q46654951 | ||
Nuclear side conformational changes in the nuclear pore complex following calcium release from the nuclear membrane | Q46735884 | ||
Binding dynamics of isolated nucleoporin repeat regions to importin-beta | Q46843299 | ||
Nanomechanical basis of selective gating by the nuclear pore complex | Q46966189 | ||
Karyopherins and kissing cousins | Q47721363 | ||
AFM force measurements on microtubule-associated proteins: the projection domain exerts a long-range repulsive force | Q48773095 | ||
Domain topology of the p62 complex within the 3-D architecture of the nuclear pore complex. | Q48791551 | ||
Domain-specific antibodies reveal multiple-site topology of Nup153 within the nuclear pore complex | Q48841715 | ||
Calcium-mediated structural changes of native nuclear pore complexes monitored by time-lapse atomic force microscopy | Q48921292 | ||
The location of the transport gate in the nuclear pore complex. | Q48945948 | ||
Nanomechanical interactions of phenylalanine-glycine nucleoporins studied by single molecule force-volume spectroscopy | Q50165583 | ||
Changes in nucleoporin domain topology in response to chemical effectors. | Q50645127 | ||
Passive and facilitated transport in nuclear pore complexes is largely uncoupled. | Q50705004 | ||
Fine structure of the pore-annulus complex in the nuclear envelope and annulate lamellae of germ cells | Q52507011 | ||
Cell-cycle-dependent dynamics of nuclear pores: pore-free islands and lamins. | Q53590705 | ||
Nuclear Pore Complex Structure and Dynamics Revealed by Cryoelectron Tomography | Q57793026 | ||
A Saturated FG-Repeat Hydrogel Can Reproduce the Permeability Properties of Nuclear Pore Complexes | Q58076940 | ||
FG-Rich Repeats of Nuclear Pore Proteins Form a Three-Dimensional Meshwork with Hydrogel-Like Properties | Q58076963 | ||
The ultrastructure of the nuclear envelope of amphibian oocytes: a reinvestigation. II. The immature oocyte and dynamic aspects | Q71429872 | ||
Entropic exclusion by neurofilament sidearms: a mechanism for maintaining interfilament spacing | Q74020158 | ||
Association of nuclear pore FG-repeat domains to NTF2 import and export complexes | Q79425999 | ||
Cse1p-binding dynamics reveal a binding pattern for FG-repeat nucleoporins on transport receptors | Q80794608 | ||
The nuclear pore complex up close | Q36456427 | ||
Dynamic nuclear pore complexes: life on the edge. | Q36508009 | ||
The nuclear pore complex: oily spaghetti or gummy bear? | Q36908126 | ||
Nuclear pore complex number and distribution throughout the Saccharomyces cerevisiae cell cycle by three-dimensional reconstruction from electron micrographs of nuclear envelopes | Q36941909 | ||
Distinct functional domains within nucleoporins Nup153 and Nup98 mediate transcription-dependent mobility. | Q37221202 | ||
Adsorbed gels versus brushes: viscoelastic differences | Q37636096 | ||
Functional organization of the nuclear envelope | Q38195057 | ||
Nup214 is required for CRM1-dependent nuclear protein export in vivo | Q38411212 | ||
The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion | Q39647313 | ||
Distinct functions of the Drosophila Nup153 and Nup214 FG domains in nuclear protein transport | Q39744547 | ||
Structure, biochemistry, and functions of the nuclear envelope. | Q39952726 | ||
Modulation of nuclear pore topology by transport modifiers | Q40227899 | ||
Quantitative topographical analysis of nuclear pore complex function using scanning force microscopy | Q40264816 | ||
Macromolecular crowding: biochemical, biophysical, and physiological consequences | Q40488946 | ||
Toward a molecular understanding of the structure and function of the nuclear pore complex. | Q40943127 | ||
Molecular dissection of the nuclear pore complex | Q41063786 | ||
Snapshots of nuclear pore complexes in action captured by cryo-electron tomography | Q41624126 | ||
Nup98 is a mobile nucleoporin with transcription-dependent dynamics | Q30475776 | ||
Reversibility in nucleocytoplasmic transport | Q30479838 | ||
Nuclear import time and transport efficiency depend on importin beta concentration. | Q30480491 | ||
Nuclear hourglass technique: an approach that detects electrically open nuclear pores in Xenopus laevis oocyte | Q30482126 | ||
Imaging of single-molecule translocation through nuclear pore complexes | Q30832298 | ||
Experimental studies on amphibian oocyte nuclei. I. Investigation of the structure of the nuclear membrane by means of the electron microscope | Q33197613 | ||
Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport | Q33246576 | ||
Efficiency, selectivity, and robustness of nucleocytoplasmic transport | Q33290827 | ||
The maximal size of protein to diffuse through the nuclear pore is larger than 60kDa | Q33781297 | ||
Nuclear pore complex is able to transport macromolecules with diameters of about 39 nm | Q33953659 | ||
Visualization of transport-related configurations of the nuclear pore transporter | Q34126294 | ||
Electrical dimension of the nuclear envelope. | Q34127742 | ||
Conformational changes of the in situ nuclear pore complex | Q34170828 | ||
The nuclear pore complex as a transport machine. | Q34205241 | ||
Simple fold composition and modular architecture of the nuclear pore complex | Q34478878 | ||
A general amphipathic alpha-helical motif for sensing membrane curvature. | Q34601480 | ||
The nuclear pore complex: nucleocytoplasmic transport and beyond | Q35564601 | ||
Virtual gating and nuclear transport: the hole picture | Q35587487 | ||
Translocation through the nuclear pore complex: selectivity and speed by reduction-of-dimensionality | Q36090722 | ||
Modularity within the architecture of the nuclear pore complex. | Q36101124 | ||
Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo. | Q36119204 | ||
Octagonal nuclear pores | Q36189025 | ||
On the octagonality of the nuclear pore complex | Q36192246 | ||
On the attachment of the nuclear pore complex | Q36196142 | ||
Protein import through the nuclear pore complex is a multistep process | Q36221436 | ||
Interactions and structure of the nuclear pore complex revealed by cryo-electron microscopy | Q36221543 | ||
Architecture of the Xenopus nuclear pore complex revealed by three-dimensional cryo-electron microscopy. | Q36232581 | ||
Versatility at the nuclear pore complex: lessons learned from the nucleoporin Nup153. | Q36245336 | ||
The FG-repeat asymmetry of the nuclear pore complex is dispensable for bulk nucleocytoplasmic transport in vivo | Q36322759 | ||
Importin beta contains a COOH-terminal nucleoporin binding region important for nuclear transport | Q36322989 | ||
The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import | Q36323649 | ||
From the trap to the basket: getting to the bottom of the nuclear pore complex | Q36364506 | ||
The direction of transport through the nuclear pore can be inverted | Q36428044 | ||
P433 | issue | 2 | |
P921 | main subject | cell | Q7868 |
biomedical investigative technique | Q66648976 | ||
P304 | page(s) | 105-116 | |
P577 | publication date | 2008-01-29 | |
2008-02-01 | |||
P1433 | published in | Histochemistry and Cell Biology | Q1524012 |
P1476 | title | Towards reconciling structure and function in the nuclear pore complex | |
P478 | volume | 129 |
Q30496966 | A bimodal distribution of two distinct categories of intrinsically disordered structures with separate functions in FG nucleoporins |
Q41960842 | Biophysical coarse-grained modeling provides insights into transport through the nuclear pore complex |
Q27333529 | Brownian dynamics simulation of nucleocytoplasmic transport: a coarse-grained model for the functional state of the nuclear pore complex |
Q37870091 | Calcium regulation of nucleocytoplasmic transport |
Q50276465 | Challenges in the Development of Functional Assays of Membrane Proteins. |
Q43714423 | Charge versus sequence for nuclear/nucleolar localization of plant ribosomal proteins |
Q26779126 | Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint |
Q37756152 | Converging on the function of intrinsically disordered nucleoporins in the nuclear pore complex |
Q28469358 | Cooperative Interactions between Different Classes of Disordered Proteins Play a Functional Role in the Nuclear Pore Complex of Baker's Yeast |
Q33708397 | Cryoelectron tomography of eukaryotic cells. |
Q33354517 | Depletion of nucleoporins from HeLa nuclear pore complexes to facilitate the production of ghost pores for in vitro reconstitution |
Q36161728 | Domain topology of nucleoporin Nup98 within the nuclear pore complex |
Q59355849 | Domains of bovine adenovirus-3 protein 22K involved in interacting with viral protein 52K and cellular importins α-5/α-7 |
Q26851949 | Dynamics and diverse functions of nuclear pore complex proteins |
Q54453207 | Dynamics of single mRNP nucleocytoplasmic transport and export through the nuclear pore in living cells. |
Q27936599 | ER membrane-bending proteins are necessary for de novo nuclear pore formation |
Q37279223 | Effects of multiple occupancy and interparticle interactions on selective transport through narrow channels: theory versus experiment |
Q33604697 | Enhancement of transport selectivity through nano-channels by non-specific competition |
Q36254589 | Evolutionarily Conserved Sequence Features Regulate the Formation of the FG Network at the Center of the Nuclear Pore Complex |
Q52699670 | Exclusion of mRNPs and ribosomal particles from a thin zone beneath the nuclear envelope revealed upon inhibition of transport. |
Q35975179 | Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype |
Q37641143 | Extending the knowledge in histochemistry and cell biology |
Q27933306 | Facilitated transport and diffusion take distinct spatial routes through the nuclear pore complex |
Q37373601 | Functionalization of a nanopore: the nuclear pore complex paradigm |
Q30439071 | Herpes simplex virus replication: roles of viral proteins and nucleoporins in capsid-nucleus attachment |
Q34410193 | Inhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agents |
Q33358663 | Intramolecular cohesion of coils mediated by phenylalanine--glycine motifs in the natively unfolded domain of a nucleoporin |
Q37735568 | Ion channels at the nucleus: electrophysiology meets the genome |
Q35119530 | Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients. |
Q30575768 | Large cargo transport by nuclear pores: implications for the spatial organization of FG-nucleoporins |
Q38747471 | Localisation of Nup153 and SENP1 to nuclear pore complexes is required for 53BP1-mediated DNA double-strand break repair |
Q39324081 | Mapping of nuclear import signal and importin α3 binding regions of 52K protein of bovine adenovirus-3. |
Q35117017 | Mapping the amino acid properties of constituent nucleoporins onto the yeast nuclear pore complex |
Q33635365 | Mechanisms and signals for the nuclear import of proteins |
Q37127856 | Mengovirus-induced rearrangement of the nuclear pore complex: hijacking cellular phosphorylation machinery |
Q53043508 | Miniseries: Illustrating the machinery of life: Eukaryotic cell panorama. |
Q61812276 | NUP214 in Leukemia: It's More than Transport |
Q27012444 | Nuclear export of proteins and drug resistance in cancer |
Q47155700 | Nuclear pore complex plasticity during developmental process as revealed by super-resolution microscopy. |
Q33595850 | Nuclear pore complex protein sequences determine overall copolymer brush structure and function |
Q37252910 | Nuclear pore proteins and cancer |
Q37809760 | Nucleocytoplasmic mRNP export is an integral part of mRNP biogenesis |
Q59072645 | Nucleoporin Gene Fusions and Hematopoietic Malignancies |
Q33822225 | Perspective on the metazoan nuclear pore complex |
Q34412386 | Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane |
Q30486113 | Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy |
Q39430925 | Protein Transport by the Nuclear Pore Complex: Simple Biophysics of a Complex Biomachine |
Q36921879 | Simple biophysics underpins collective conformations of the intrinsically disordered proteins of the Nuclear Pore Complex |
Q30502699 | Single molecule studies of nucleocytoplasmic transport |
Q30482446 | Single-molecule measurements of importin alpha/cargo complex dissociation at the nuclear pore |
Q36070958 | Single-molecule studies of nucleocytoplasmic transport: from one dimension to three dimensions. |
Q37317937 | State-of-the-art technologies, current opinions and developments, and novel findings: news from the field of histochemistry and cell biology |
Q41716632 | Structural characterization of altered nucleoporin Nup153 expression in human cells by thin-section electron microscopy |
Q39405141 | Structural features of transversal barrier in central channel of nuclear pore complex |
Q37231242 | Structure, dynamics and function of nuclear pore complexes |
Q27657007 | Structures of the tRNA export factor in the nuclear and cytosolic states |
Q28477538 | The Ccr4-Not complex interacts with the mRNA export machinery |
Q37829128 | The nuclear envelope in the plant cell cycle: structure, function and regulation. |
Q34558155 | The nucleoporin Nup153 affects spindle checkpoint activity due to an association with Mad1. |
Q34749215 | The nucleoporin Nup88 is interacting with nuclear lamin A. |
Q37836613 | The role of nuclear pore complex in tumor microenvironment and metastasis |
Q28273109 | Three-dimensional visualization of gammaherpesvirus life cycle in host cells by electron tomography |
Q30488448 | Transport-related structures and processes of the nuclear pore complex studied through molecular dynamics |
Q42268108 | Transportin mediates nuclear entry of DNA in vertebrate systems |
Q37346006 | Transportin regulates major mitotic assembly events: from spindle to nuclear pore assembly |
Q30430017 | Uncoupling uncoating of herpes simplex virus genomes from their nuclear import and gene expression. |
Q47549703 | Verdinexor Targeting of CRM1 is a Promising Therapeutic Approach against RSV and Influenza Viruses |
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