Novel Use of Hydroxyurea in an African Region With Malaria: Protocol for a Randomized Controlled Clinical Trial

scientific article published on 23 June 2016

Novel Use of Hydroxyurea in an African Region With Malaria: Protocol for a Randomized Controlled Clinical Trial is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2196/RESPROT.5599
P932PMC publication ID4937184
P698PubMed publication ID27339303

P50authorTeresa LathamQ56800266
Juliana N AnyanwuQ96177127
Olatundun WilliamsQ96177128
Casey L SautterQ96177129
Heather HumeQ96177130
Christopher NdugwaQ96177157
Phillip KasiryeQ42853043
Robert O OpokaQ56784770
Russell E WareQ56785312
Chandy C. JohnQ56785321
P2093author name stringHeather Hume
Casey L Sautter
Christopher Ndugwa
Juliana N Anyanwu
Olatundun Williams
Phillip Kasirye
P2860cites workQuality of parental consent in a Ugandan malaria studyQ56919137
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Differential modulation of adhesion molecule expression by hydroxycarbamide in human endothelial cells from the micro- and macrocirculation: potential implications in sickle cell disease vasoocclusive eventsQ34750534
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Systematic review of current and emerging strategies for reducing morbidity from malaria in sickle cell diseaseQ38074184
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Fetal haemoglobin and malariaQ39467147
A pilot study of hydroxyurea to prevent chronic organ damage in young children with sickle cell anemia.Q41734468
Nitric oxide donor properties of hydroxyurea in patients with sickle cell diseaseQ43883731
Hydroxyurea downregulates endothelin-1 gene expression and upregulates ICAM-1 gene expression in cultured human endothelial cells.Q43977840
Plasma levels of TNF-alpha in sickle cell patients receiving hydroxyureaQ44765608
Altered levels of pro-inflammatory cytokines in sickle cell disease patients during vaso-occlusive crises and the steady state condition.Q44805631
Increased levels of soluble ICAM-1 in the plasma of sickle cell patients are reversed by hydroxyureaQ44999407
Increased adhesive properties of neutrophils in sickle cell disease may be reversed by pharmacological nitric oxide donationQ46713968
Editorial: Popular concerns about medical research projects in sub-Saharan Africa--a critical voice in debates about medical research ethicsQ47197299
Cytokines and soluble adhesion molecules in sickle cell anemia patients during hydroxyurea therapyQ47738528
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Effects of hydroxyurea on malaria, parasite growth and adhesion in experimental models.Q48036749
Understanding of informed consent in a low-income setting: three case studies from the Kenyan CoastQ48519507
P433issue2
P921main subjectmalariaQ12156
hydroxyureaQ212272
P304page(s)e110
P577publication date2016-06-23
P1433published inJMIR research protocolsQ27724721
P1476titleNovel Use of Hydroxyurea in an African Region With Malaria: Protocol for a Randomized Controlled Clinical Trial
P478volume5

Reverse relations

cites work (P2860)
Q41676261Cell Cycle Inhibition To Treat Sleeping Sickness
Q38692796Hydroxyurea (hydroxycarbamide) for sickle cell disease.
Q37585014Sickle cell anemia in sub-Saharan Africa: advancing the clinical paradigm through partnerships and research.
Q52795486Sickle cell disease.
Q42374716Sickle cell disease: Status with particular reference to India

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