review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Andrew Schally | Q141147 |
Trinad Chakraborty | Q90390457 | ||
Norman L Block | Q102145476 | ||
Supriya Sridhar | Q114901854 | ||
Helena Pillich | Q125320923 | ||
Aluya Oseghale | Q125321116 | ||
Ferenc Rick | Q42849967 | ||
Rudolf Lucas | Q56636149 | ||
Istvan Czikora | Q58903713 | ||
P2093 | author name string | Boris Gorshkov | |
Evgeny Zemskov | |||
Maritza Romero | |||
Jonathan Lawson | |||
Martin Leustik | |||
Alexander Verin | |||
Umapathy Siddaramappa | |||
P2860 | cites work | Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro | Q81234083 |
Receptor activator of nuclear factor (NF)-kappaB ligand (RANKL) increases vascular permeability: impaired permeability and angiogenesis in eNOS-deficient mice | Q79233971 | ||
Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice | Q80160163 | ||
Antagonists of growth-hormone-releasing hormone: an emerging new therapy for cancer | Q37033860 | ||
Inhibition of in vitro human lymphocyte response by the pneumococcal toxin pneumolysin | Q37042245 | ||
NADPH oxidase-derived reactive oxygen species in the regulation of endothelial phenotype | Q37085294 | ||
Inhibition of human polymorphonuclear leukocyte respiratory burst, bactericidal activity, and migration by pneumolysin | Q37105935 | ||
Regulation of endothelial junctional permeability | Q37122803 | ||
Production and purification of Streptococcus pneumoniae hemolysin (pneumolysin) | Q37135636 | ||
TNF: a moonlighting protein at the interface between cancer and infection | Q37175520 | ||
Claudin-4 augments alveolar epithelial barrier function and is induced in acute lung injury | Q37343892 | ||
Acute bacterial pneumonia in rats increases alveolar epithelial fluid clearance by a tumor necrosis factor-alpha-dependent mechanism | Q37362616 | ||
The Dual Role of TNF in Pulmonary Edema | Q37824251 | ||
Emerging themes of cAMP regulation of the pulmonary endothelial barrier | Q37845025 | ||
Mapping the lectin-like activity of tumor necrosis factor | Q38311192 | ||
Dichotomal role of TNF in experimental pulmonary edema reabsorption | Q38321813 | ||
Characterization of pneumolysin from Streptococcus pneumoniae, interacting with carbohydrate moiety and cholesterol as a component of cell membrane | Q39508458 | ||
Protein kinase A and mitogen-activated protein kinase pathways mediate cAMP induction of alpha-epithelial Na+ channels (alpha-ENaC). | Q40062449 | ||
Production and characterization of neutralizing and nonneutralizing monoclonal antibodies against listeriolysin O. | Q40156355 | ||
Pleural-pulmonary aspects of Listeria monocytogenes infection | Q40269926 | ||
Involvement of microtubules and Rho pathway in TGF-beta1-induced lung vascular barrier dysfunction | Q40435805 | ||
Growth hormone-releasing hormone: synthesis and signaling. | Q40519101 | ||
Role of protein kinase C isoforms in rat epididymal microvascular endothelial barrier function | Q40653322 | ||
cAMP-induced changes of apical membrane potentials of confluent H441 monolayers | Q40654038 | ||
Pneumococcal Hemolysin: The Preparation of Concentrates, and Their Action on Red Cells. | Q40696871 | ||
Listeriolysin of Listeria monocytogenes forms Ca2+-permeable pores leading to intracellular Ca2+ oscillations | Q40711338 | ||
Mechanisms of TNF-alpha stimulation of amiloride-sensitive sodium transport across alveolar epithelium | Q40806572 | ||
Diabetes-induced coronary vascular dysfunction involves increased arginase activity | Q41817278 | ||
PNEUMOCOCCUS HEMOTOXIN. | Q41843485 | ||
STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : IV. OXIDATION OF HEMOTOXIN IN STERILE EXTRACTS OF PNEUMOCOCCUS. | Q42144000 | ||
Functional identification of the alveolar edema reabsorption activity of murine tumor necrosis factor-alpha | Q42169101 | ||
Fluid transport across cultured rat alveolar epithelial cells: a novel in vitro system | Q42457845 | ||
Constitutive eNOS-derived nitric oxide is a determinant of endothelial junctional integrity | Q42482474 | ||
Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function | Q43579834 | ||
Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome | Q43616371 | ||
Role of platelet-activating factor in pneumolysin-induced acute lung injury | Q44400936 | ||
Downregulation of ENaC activity and expression by TNF-α in alveolar epithelial cells | Q44599680 | ||
Novel role of microtubules in thrombin-induced endothelial barrier dysfunction | Q45171532 | ||
The lectin-like domain of tumor necrosis factor-alpha improves alveolar fluid balance in injured isolated rabbit lungs | Q46628233 | ||
Differential roles of PKCalpha and PKCepsilon in controlling the gene expression of Nox4 in human endothelial cells | Q46740822 | ||
Effects of macrolides on pneumolysin of macrolide-resistant Streptococcus pneumoniae | Q46925781 | ||
Presence of nonhemolytic pneumolysin in serotypes of Streptococcus pneumoniae associated with disease outbreaks | Q48078155 | ||
Differential activations of PKC/PKA related to microvasculopathy in diabetic GK rats | Q48850018 | ||
Epidemiology and etiology of childhood pneumonia | Q22241278 | ||
Isolation and sequencing of cDNAs for splice variants of growth hormone-releasing hormone receptors from human cancers. | Q24652328 | ||
More than a pore: the cellular response to cholesterol-dependent cytolysins | Q27023593 | ||
Uromodulin (Tamm-Horsfall glycoprotein): a renal ligand for lymphokines | Q28299295 | ||
Growth-hormone-releasing hormone | Q30452244 | ||
Role of VASP in reestablishment of epithelial tight junction assembly after Ca2+ switch | Q30706595 | ||
Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway | Q33552508 | ||
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4. | Q33750041 | ||
Specificity of the autolysin of Streptococcus (Diplococcus) pneumoniae | Q33793950 | ||
The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin | Q33996189 | ||
Pneumococcal virulence factors: structure and function | Q34010335 | ||
Upper and lower respiratory tract infection by Streptococcus pneumoniae is affected by pneumolysin deficiency and differences in capsule type. | Q34123722 | ||
Synthesis and biological evaluation of superactive agonists of growth hormone-releasing hormone | Q34270999 | ||
Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space | Q34331893 | ||
Cytoskeletal regulation of pulmonary vascular permeability | Q34377340 | ||
Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions | Q34724964 | ||
Protein kinase C modulates pulmonary endothelial permeability: a paradigm for acute lung injury | Q35062604 | ||
Contribution of autolysin to virulence of Streptococcus pneumoniae | Q35099865 | ||
Effect of Streptococcus pneumoniae on human respiratory epithelium in vitro | Q35111190 | ||
Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae | Q35111311 | ||
Interaction of pneumolysin-sufficient and -deficient isogenic variants of Streptococcus pneumoniae with human respiratory mucosa. | Q35383517 | ||
Neutralizing monoclonal antibodies against listeriolysin: mapping of epitopes involved in pore formation | Q35501235 | ||
Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin | Q35669797 | ||
Agonist of growth hormone-releasing hormone reduces pneumolysin-induced pulmonary permeability edema | Q35751094 | ||
Regulators of endothelial and epithelial barrier integrity and function in acute lung injury | Q35760657 | ||
Regulatory effects of iNOS on acute lung inflammatory responses in mice | Q35843243 | ||
Specific uptake of tumor necrosis factor-alpha is involved in growth control of Trypanosoma brucei. | Q36274117 | ||
Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability | Q36369969 | ||
Direct transmembrane interaction between actin and the pore-competent, cholesterol-dependent cytolysin pneumolysin | Q36860052 | ||
Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA | Q36977651 | ||
The lectin-like domain of tumor necrosis factor improves lung function after rat lung transplantation--potential role for a reduction in reactive oxygen species generation | Q36995337 | ||
Cloning and expression in Escherichia coli of the Streptococcus pneumoniae gene encoding pneumolysin | Q37011884 | ||
Molecular cloning, characterization, and complete nucleotide sequence of the gene for pneumolysin, the sulfhydryl-activated toxin of Streptococcus pneumoniae | Q37018660 | ||
Purification of growth hormone-releasing factor from beef hypothalamus. | Q51233029 | ||
The effects of pneumolysin and hydrogen peroxide, alone and in combination, on human ciliated epithelium in vitro. | Q51706202 | ||
Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia. | Q51804034 | ||
Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs. | Q52891231 | ||
Contribution of individual tryptophan residues to the structure and activity of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin. | Q54577935 | ||
Management of Community-acquired Pneumonia in Adults | Q57237808 | ||
The lectin-like domain of tumor necrosis factor-α increases membrane conductance in microvascular endothelial cells and peritoneal macrophages | Q58858838 | ||
Effect of insertional inactivation of the genes encoding pneumolysin and autolysin on the virulence of Streptococcus pneumoniae type 3 | Q67516541 | ||
Pneumolysin induces the salient histologic features of pneumococcal infection in the rat lung in vivo | Q67903731 | ||
Expression of the pneumolysin gene in Escherichia coli: rapid purification and biological properties | Q69481233 | ||
Searching for autolysin functions. Characterization of a pneumococcal mutant deleted in the lytA gene | Q69568308 | ||
Inhibition of human monocyte respiratory burst, degranulation, phospholipid methylation and bactericidal activity by pneumolysin | Q69723289 | ||
Distinct roles for pneumolysin's cytotoxic and complement activities in the pathogenesis of pneumococcal pneumonia | Q71046224 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Streptococcus pneumoniae | Q221179 |
lung | Q7886 | ||
pneumonia | Q12192 | ||
streptolysins | Q76388187 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 1244-1260 | |
P577 | publication date | 2013-07-15 | |
P1433 | published in | Toxins | Q15724569 |
P1476 | title | Mini-review: novel therapeutic strategies to blunt actions of pneumolysin in the lungs | |
P478 | volume | 5 |
Q91770164 | CAL02, a novel antitoxin liposomal agent, in severe pneumococcal pneumonia: a first-in-human, double-blind, placebo-controlled, randomised trial |
Q27684952 | Conformational Analysis of the Streptococcus pneumoniae Hyaluronate Lyase and Characterization of Its Hyaluronan-specific Carbohydrate-binding Module |
Q47651769 | Cytokine-Ion Channel Interactions in Pulmonary Inflammation |
Q35953618 | Deletion analysis of Streptococcus pneumoniae late competence genes distinguishes virulence determinants that are dependent or independent of competence induction |
Q55287568 | Hsp70 Suppresses Mitochondrial Reactive Oxygen Species and Preserves Pulmonary Microvascular Barrier Integrity Following Exposure to Bacterial Toxins. |
Q35603391 | Inhalation therapy with the synthetic TIP-like peptide AP318 attenuates pulmonary inflammation in a porcine sepsis model |
Q53269550 | Liposomes as novel anti-infectives targeting bacterial virulence factors? |
Q53693867 | Multifaceted Role of Pneumolysin in the Pathogenesis of Myocardial Injury in Community-Acquired Pneumonia. |
Q35833122 | New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor |
Q36189529 | Novel GHRH antagonists suppress the growth of human malignant melanoma by restoring nuclear p27 function. |
Q60952635 | Pharmacological Targeting of Pore-Forming Toxins as Adjunctive Therapy for Invasive Bacterial Infection |
Q36741309 | Pneumococcal Pneumolysin Induces DNA Damage and Cell Cycle Arrest |
Q33601853 | Randomized controlled study of the safety and immunogenicity of pneumococcal vaccine formulations containing PhtD and detoxified pneumolysin with alum or adjuvant system AS02V in elderly adults |
Q38598360 | Streptococcal toxins: role in pathogenesis and disease |
Q42214099 | TBX21 participates in innate immune response by regulating Toll-like receptor 2 expression in Streptococcus pneumoniae infections |
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