High-fat diet induces changes in adipose tissue trans-4-oxo-2-nonenal and trans-4-hydroxy-2-nonenal levels in a depot-specific manner

scientific article published on 28 May 2013

High-fat diet induces changes in adipose tissue trans-4-oxo-2-nonenal and trans-4-hydroxy-2-nonenal levels in a depot-specific manner is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FREERADBIOMED.2013.05.030
P932PMC publication ID3737572
P698PubMed publication ID23726997

P2093author name stringDavid A Bernlohr
Eric K Long
Dalay M Olson
P2860cites workOxidative stress and covalent modification of protein with bioactive aldehydesQ24649676
Implication of inflammatory signaling pathways in obesity-induced insulin resistanceQ27500365
Substrate Specificity Combined with Stereopromiscuity in Glutathione Transferase A4-4-Dependent Metabolism of 4-HydroxynonenalQ27659040
Model for the exceptional reactivity of peroxiredoxins 2 and 3 with hydrogen peroxide: a kinetic and computational studyQ28115866
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydesQ28241500
Oxygen radical chemistry of polyunsaturated fatty acidsQ28270970
Role of aldehyde dehydrogenase isozymes in the defense of rat lens and human lens epithelial cells against oxidative stressQ28567370
Increased oxidative stress in obesity and its impact on metabolic syndromeQ29012150
Macrophages, inflammation, and insulin resistanceQ29614351
Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenalQ30757632
Analysis of a Model Reaction System Containing Cysteine and (E)-2-Methyl-2-butenal, (E)-2-Hexenal, or Mesityl OxideQ30883972
Covalent adduction of nucleophilic amino acids by 4-hydroxynonenal and 4-oxononenalQ31132956
Covalent modification of epithelial fatty acid-binding protein by 4-hydroxynonenal in vitro and in vivo. Evidence for a role in antioxidant biologyQ33184894
Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenalQ33268342
Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stressQ33642761
Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunctionQ33803419
Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer diseaseQ33897525
Comparison of glutathione peroxidase 1 and peroxiredoxin 6 in protection against oxidative stress in the mouse lungQ34162943
Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes.Q34285754
Mitochondrial DNA damage and dysfunction, and oxidative stress are associated with endoplasmic reticulum stress, protein degradation and apoptosis in high fat diet-induced insulin resistance miceQ34559096
Stress, visceral obesity, and metabolic complicationsQ34587960
Basic aspects of the biochemical reactivity of 4-hydroxynonenalQ35189509
Role of 4-hydroxynonenal in stress-mediated apoptosis signalingQ35189540
Peroxiredoxin 3 is a key molecule regulating adipocyte oxidative stress, mitochondrial biogenesis, and adipokine expression.Q35604034
Increased macrophage migration into adipose tissue in obese miceQ35696560
Interactions of glutathione transferases with 4-hydroxynonenalQ35731685
Inflammation, insulin resistance, and obesity.Q35918777
Protein carbonylation and metabolic control systemsQ36129390
Increased adipose protein carbonylation in human obesityQ36279150
Protein carbonylation and adipocyte mitochondrial function.Q36294734
Mitochondrial effects of lipid-derived neurotoxins.Q36961326
4-Hydroxynonenal-protein adducts: A reliable biomarker of lipid oxidation in liver diseases.Q37044814
A lipid-derived endogenous inducer of COX-2: a bridge between inflammation and oxidative stress.Q37165141
Differential contribution of the mitochondrial respiratory chain complexes to reactive oxygen species production by redox cycling agents implicated in parkinsonismQ37420410
TNF-alpha and obesityQ37696085
The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4.Q39430933
A lipid peroxidation-derived inflammatory mediator: identification of 4-hydroxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophagesQ40517859
4-Hydroxynonenal and fat storage: A paradoxical pro-obesity mechanism?Q42882285
Consumption of a high glycemic index diet increases abdominal adiposity but does not influence adipose tissue pro-oxidant and antioxidant gene expression in C57BL/6 mice.Q43130905
4-Hydroxy-2-nonenal is a powerful endogenous inhibitor of endothelial responseQ43636560
Role of p38 mitogen-activated protein kinase in the 4-hydroxy-2-nonenal-induced cyclooxygenase-2 expressionQ43857537
Gene expression in visceral and subcutaneous adipose tissue in overweight womenQ44200271
Effects of dietary fat and zinc on adiposity, serum leptin and adipose fatty acid composition in C57BL/6J miceQ44297579
Trans-4-oxo-2-nonenal potently alters mitochondrial functionQ44390596
Degradation of glyceraldehyde-3-phosphate dehydrogenase triggered by 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenalQ46501992
Structural characterization of alpha,beta-unsaturated aldehydes by GC/MS is dependent upon ionization methodQ46508721
Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's diseaseQ46580300
Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in miceQ46724603
Residue-specific adduction of tubulin by 4-hydroxynonenal and 4-oxononenal causes cross-linking and inhibits polymerizationQ48105013
Dietary sandalwood seed oil modifies fatty acid composition of mouse adipose tissue, brain, and liverQ48623923
Differential effects of high-fat-diet rich in lard oil or soybean oil on osteopontin expression and inflammation of adipose tissue in diet-induced obese rats.Q51353294
Relationship of oxidative stress with obesity and its role in obesity induced metabolic syndrome.Q51354264
The Human Visceral Fat Depot Has a Unique Inflammatory ProfileQ61774862
Determination of the lipid peroxidation product (E)-4-hydroxy-2-nonenal in clinical samples by gas chromatography--negative-ion chemical ionisation mass spectrometry of the O-pentafluorobenzyl oxime.Q67212130
Determination of the lipid peroxidation product trans-4-hydroxy-2-nonenal in biological samples by high-performance liquid chromatography and combined capillary column gas chromatography-negative-ion chemical ionisation mass spectrometryQ69652599
Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross-linking reactionQ70614534
Pathophysiology and pathogenesis of visceral fat obesityQ70951912
Hepatic aldehyde dehydrogenases and lipid peroxidationQ71082287
4-Hydroxynonenal formation during ischemia and reperfusion of rat small intestineQ71965074
Genotoxic properties of 4-hydroxyalkenals and analogous aldehydesQ72104243
Effect of 4-hydroxy-2,3-trans-nonenal and related aldehydes on phospholipase C activity of rat neutrophilsQ72165445
Serum 4-hydroxy-2-nonenal-modified albumin is elevated in patients with type 2 diabetes mellitusQ73524862
Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidationQ74217134
Reactions of 1-methyl-2-phenylindole with malondialdehyde and 4-hydroxyalkenals. Analytical applications to a colorimetric assay of lipid peroxidationQ77431145
Glutathione peroxidase3 of Saccharomyces cerevisiae protects phospholipids during cadmium-induced oxidative stressQ83180933
Depot-specific overexpression of proinflammatory, redox, endothelial cell, and angiogenic genes in epicardial fat adjacent to severe stable coronary atherosclerosisQ84376291
P304page(s)390-398
P577publication date2013-05-28
P1433published inFree Radical Biology and MedicineQ5500023
P1476titleHigh-fat diet induces changes in adipose tissue trans-4-oxo-2-nonenal and trans-4-hydroxy-2-nonenal levels in a depot-specific manner
P478volume63

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cites work (P2860)
Q49339905A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction.
Q51009537ALDH2*2 Allele is a Negative Risk Factor for Cerebral Infarction in Chinese Women.
Q40955171Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis
Q90621939Adipose oxidative stress and protein carbonylation
Q28249276Branched-chain amino acids in metabolic signalling and insulin resistance
Q95661178Chromatin as a key consumer in the metabolite economy
Q60916152Disruption of the hippocampal and hypothalamic blood-brain barrier in a diet-induced obese model of type II diabetes: prevention and treatment by the mitochondrial carbonic anhydrase inhibitor, topiramate
Q41540768Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet.
Q27329108Free fatty acids, lipopolysaccharide and IL-1α induce adipocyte manganese superoxide dismutase which is increased in visceral adipose tissues of obese rodents
Q38614144Glutathionyl systems and metabolic dysfunction in obesity
Q34017989Impact of chronic low to moderate alcohol consumption on blood lipid and heart energy profile in acetaldehyde dehydrogenase 2-deficient mice
Q46762183In adipose tissue, increased mitochondrial emission of reactive oxygen species is important for short-term high-fat diet-induced insulin resistance in mice.
Q35140256Inflammation and ER stress regulate branched-chain amino acid uptake and metabolism in adipocytes
Q34001327Metabolic remodeling of white adipose tissue in obesity
Q90254951Obesity-induced protein carbonylation in murine adipose tissue regulates the DNA-binding domain of nuclear zinc finger proteins
Q90699040Oxidative modifications of mitochondrial complex II are associated with insulin resistance of visceral fat in obesity
Q38786583Oxidative stress and lipotoxicity
Q34038044Oxidative stress and metabolic pathologies: from an adipocentric point of view.
Q33568689Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics
Q42701691Short-term vitamin E treatment impairs reactive oxygen species signaling required for adipose tissue expansion, resulting in fatty liver and insulin resistance in obese mice
Q35571550Site-specific, intramolecular cross-linking of Pin1 active site residues by the lipid electrophile 4-oxo-2-nonenal
Q89620129The Impact of Oxidative Stress on Adipose Tissue Energy Balance
Q26797301Why does obesity promote cancer? Epidemiology, biology, and open questions

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