Increased extracellular pressure enhances cancer cell integrin-binding affinity through phosphorylation of beta1-integrin at threonine 788/789

scientific article

Increased extracellular pressure enhances cancer cell integrin-binding affinity through phosphorylation of beta1-integrin at threonine 788/789 is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPCELL.00355.2008
P932PMC publication ID2637001
P698PubMed publication ID19005162
P5875ResearchGate publication ID23469589

P2093author name stringJinhua Li
Marc D Basson
Yasmina Laouar
Keri L Schaubert
Christopher P Gayer
David H Craig
Yanzhang Wei
P2860cites workIntegrating with integrinsQ24620638
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Mutational analysis of the potential phosphorylation sites in the cytoplasmic domain of integrin beta1A. Requirement for threonines 788-789 in receptor activationQ32085891
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Elevated physiologic tumor pressure promotes proliferation and chemosensitivity in human osteosarcomaQ33433095
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Treatment with okadaic acid reveals strong threonine phosphorylation of CD18 after activation of CD11/CD18 leukocyte integrins with phorbol esters or CD3 antibodiesQ71961003
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FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathwayQ79818499
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A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1Q36569275
Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes.Q37354696
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Endothelial cell injury in human saphenous veins after manipulation and tweezer graspingQ39299132
Colchicine inhibits pressure-induced tumor cell implantation within surgical wounds and enhances tumor-free survival in miceQ39950468
Increased pressure stimulates aberrant dendritic cell maturationQ40030490
Avidity modulation activates adhesion under flow and requires cooperativity among adhesion receptors.Q40264925
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Extracellular pressure stimulates colon cancer cell proliferation via a mechanism requiring PKC and tyrosine kinase signalsQ40490979
The regulation of integrin-linked kinase in human platelets: evidence for involvement in the regulation of integrin alpha 2 beta 1.Q40526832
Fusion protein from RGD peptide and Fc fragment of mouse immunoglobulin G inhibits angiogenesis in tumorQ40573323
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Serine 785 phosphorylation of the beta1 cytoplasmic domain modulates beta1A-integrin-dependent functions.Q40780244
Macrophage-enriched myristoylated alanine-rich C kinase substrate and its phosphorylation is required for the phorbol ester-stimulated diffusion of beta 2 integrin moleculesQ40884287
Cytoplasmic domain mutants of beta1 integrin, expressed in beta 1-knockout lymphoma cells, have distinct effects on adhesion, invasion and metastasisQ40894461
The actin cytoskeleton regulates LFA-1 ligand binding through avidity rather than affinity changesQ40929984
Mechanotransduction and the functional response of bone to mechanical strainQ40947864
Divalent cations and ligands induce conformational changes that are highly divergent among beta1 integrinsQ41050898
Beta 1 integrin-dependent and -independent polymerization of fibronectinQ41254786
The cellular and molecular response of cardiac myocytes to mechanical stress.Q41388060
Matrix-driven cell size change modulates aortic endothelial cell proliferation and sheet migrationQ41439205
Some comments on frequently used multiple endpoint adjustment methods in clinical trialsQ41665319
Calcium flux in neutrophils synchronizes beta2 integrin adhesive and signaling events that guide inflammatory recruitmentQ41808227
Exposure of ligand-binding sites on platelet integrin alpha IIB/beta 3 by phosphorylation of the beta 3 subunit.Q41896469
Colon cancer cell adhesion in response to Src kinase activation and actin-cytoskeleton by non-laminar shear stressQ42460761
Hypoxia activates beta(1)-integrin via ERK 1/2 and p38 MAP kinase in human vascular smooth muscle cellsQ42525269
Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocystsQ42771254
Disseminated single tumor cells as detected by real-time quantitative polymerase chain reaction represent a prognostic factor in patients undergoing surgery for colorectal cancerQ43504494
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signalingQ44136286
Alpha4beta1 integrin affinity changes govern cell adhesionQ44502569
Pressure activates colon cancer cell adhesion by inside-out focal adhesion complex and actin cytoskeletal signalingQ44709429
Integrin activation by R-ras.Q45995226
Short chain fatty acids inhibit human (SW1116) colon cancer cell invasion by reducing urokinase plasminogen activator activity and stimulating TIMP-1 and TIMP-2 activities, rather than via MMP modulationQ47721916
Viability of exfoliated colorectal carcinoma cells.Q50920819
Phenotypical plasticity of vascular smooth muscle cells-effect of in vitro and in vivo shear stress for tissue engineering of blood vessels.Q50940355
P433issue1
P921main subjectphosphorylationQ242736
P304page(s)C193-204
P577publication date2008-11-12
P1433published inAmerican Journal of Physiology - Cell PhysiologyQ2227080
P1476titleIncreased extracellular pressure enhances cancer cell integrin-binding affinity through phosphorylation of beta1-integrin at threonine 788/789
P478volume296

Reverse relations

cites work (P2860)
Q46116493Biological impact of mechanical stimuli on tumor metastasis
Q39635006Extracellular pressure stimulates adhesion of sarcoma cells via activation of focal adhesion kinase and Akt.
Q35806374Increased extracellular pressure stimulates tumor proliferation by a mechanosensitive calcium channel and PKC-β.
Q34792268Measurement of cationic and intracellular modulation of integrin binding affinity by AFM-based nanorobot.
Q33805293Proteome bioprofiles distinguish between M1 priming and activation states in human macrophages
Q43005670Specific phosphorylations transmit signals from leukocyte β2 to β1 integrins and regulate adhesion.
Q39833190The effects of increased extracellular deformation, pressure, and integrin phosphorylation on fibroblast migration
Q37407257The roles of platelet GPIIb/IIIa and alphavbeta3 integrins during HeLa cells adhesion, migration, and invasion to monolayer endothelium under static and dynamic shear flow
Q42625666beta(1)-integrin mediates pressure-stimulated phagocytosis
Q44868839α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site

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