Elevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Nonsurgical Bleeding.

scientific article published on 28 June 2016

Elevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Nonsurgical Bleeding. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1161/CIRCULATIONAHA.115.019692
P932PMC publication ID4942355
P698PubMed publication ID27354285

P50authorGene KimQ55153249
P2093author name stringGabriel Sayer
Nir Uriel
James K Liao
Valluvan Jeevanandam
Corey E Tabit
Savitri E Fedson
Phetcharat Chen
Mitchell J Coplan
P2860cites workVon Willebrand factor, angiodysplasia and angiogenesisQ26852889
High-resolution crystal structure of human protease-activated receptor 1Q27675402
Angiogenic factors in atrial fibrillation: a possible role in thrombogenesis?Q81250264
Prognostic impact of angiopoietin-2 in multiple myelomaQ88034725
Thrombin induces increased expression and secretion of angiopoietin-2 from human umbilical vein endothelial cellsQ28203283
Activation of coagulation and fibrinolytic pathways in patients with left ventricular assist devicesQ28293775
Thrombin signalling and protease-activated receptorsQ29619601
Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsisQ30541878
Thrombin upregulates the angiopoietin-Tie2 Axis: endothelial protein C receptor occupancy prevents the thrombin mobilization of angiopoietin 2 and P-selectin from Weibel-Palade bodiesQ33940353
Shear stress-activated Wnt-angiopoietin-2 signaling recapitulates vascular repair in zebrafish embryos.Q34214238
Endothelial destabilization by angiopoietin-2 via integrin β1 activation.Q35047913
Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitusQ35144163
The role of angiopoietins during angiogenesis in gliomasQ36359226
Protein kinase C-β contributes to impaired endothelial insulin signaling in humans with diabetes mellitusQ36610687
Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.Q37428684
Peripheral venous congestion causes inflammation, neurohormonal, and endothelial cell activationQ37583313
Mechanisms of bleeding and approach to patients with axial-flow left ventricular assist devices.Q37956591
Targeting the angiopoietin/Tie2 pathway: cutting tumor vessels with a double-edged sword?Q37970070
The secretion of von Willebrand factor from endothelial cells; an increasingly complicated story.Q38117737
Expression of Angiogenic Factors in Patients With Sporadic Small Bowel AngiodysplasiaQ39112499
Switching of vascular phenotypes within a murine breast cancer model induced by angiopoietin-2.Q39899888
The temporal-spatial expression of VEGF, angiopoietins-1 and 2, and Tie-2 during tumor angiogenesis and their functional correlation with tumor neovascular architectureQ40622814
Human endothelium: endovascular biopsy and molecular analysisQ40930454
Angiopoietins-1 and -2 play opposing roles in endothelial sprouting of embryoid bodies in 3D culture and their receptor Tie-2 associates with the cell-cell adhesion molecule PECAM1.Q41864287
Thrombin activity resides on LVAD Dacron inflow and outflow graftsQ42036187
Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumorsQ43054611
Angiogenic and prothrombotic markers in extensive slow-flow vascular malformations: implications for antiangiogenic/antithrombotic strategies.Q43273531
Left ventricular assist device thrombosis: another piece of the puzzle?Q43446499
Biopsy coupled to quantitative immunofluorescence: a new method to study the human vascular endotheliumQ43884350
Gastrointestinal bleeding with the HeartMate II left ventricular assist deviceQ43969687
Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumorsQ44649604
Comparison of hemodynamics in the ascending aorta between pulsatile and continuous flow left ventricular assist devices using computational fluid dynamics based on computed tomography imagesQ45328741
Computational fluid dynamics in patients with continuous-flow left ventricular assist device support show hemodynamic alterations in the ascending aortaQ45894114
Pulsatility and the risk of nonsurgical bleeding in patients supported with the continuous-flow left ventricular assist device HeartMate II.Q46360793
Gene expression of endothelial cells under pulsatile non-reversing vs. steady shear stress; comparison of nitric oxide productionQ47928164
Increased number of circulating progenitor cells after implantation of ventricular assist devicesQ48549407
Usefulness of a standard automated blood pressure monitor in patients with continuous-flow left ventricular assist devices.Q50861318
The angiopoietin pathway is modulated by PAR-1 activation on human endothelial progenitor cells.Q50933010
Neurohormonal regulation and improvement in blood glucose control: reduction of insulin requirement in patients with a nonpulsatile ventricular assist device.Q51322936
Tube formation: an in vitro matrigel angiogenesis assay.Q51757665
Enhanced thrombin regulation during warfarin therapy in children compared to adults.Q53350734
Activation of endothelial and coagulation systems in left ventricular assist device recipients.Q53370074
Tacrolimus (FK506) inhibits interleukin-1β-induced angiopoietin-1, Tie-2 receptor, and vascular endothelial growth factor through down-regulation of JNK and p38 pathway in human rheumatoid fibroblast-like synoviocytes.Q53426102
IMPACT OF CARDIAC TRANSPLANTATION ON MOLECULAR PATHOLOGY OF ET-1, VEGF-C, AND MITOCHONDRIAL METABOLISM AND MORPHOLOGY IN DILATED VERSUS ISCHEMIC CARDIOMYOPATHIC PATIENTS1Q57496988
Titanium is a highly thrombogenic biomaterial: possible implications for osteogenesisQ78155515
Formation and function of Weibel-Palade bodiesQ80240960
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectangiogenesisQ539568
P304page(s)141-152
P577publication date2016-06-28
P1433published inCirculationQ578091
P1476titleElevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Nonsurgical Bleeding
P478volume134

Reverse relations

cites work (P2860)
Q64236671Acquired von Willebrand Syndrome in Patients With Ventricular Assist Device
Q104283625Angiopoietin-2 and hemocompatibility-related adverse events during percutaneous left ventricular assist device supports
Q47267322Anticoagulation with VADs and ECMO: walking the tightrope.
Q90034535Benchtop von Willebrand Factor Testing: Comparison of Commercially Available Ventricular Assist Devices and Evaluation of Variables for a Standardized Test Method
Q42369262Bleeding in continuous flow left ventricular assist device recipients: an acquired vasculopathy?
Q54254897Blood stream infection is associated with cerebrovascular accident in patients with left ventricular assist device: a systematic review and meta-analysis.
Q49588323Contemporary Perspectives in Durable Mechanical Circulatory Support: What Did We Learn in the Last 3 Years?
Q90726839Decoupling Between Diastolic Pulmonary Artery and Pulmonary Capillary Wedge Pressures Is Associated With Right Ventricular Dysfunction and Hemocompatibility-Related Adverse Events in Patients With Left Ventricular Assist Devices
Q90085905Gut microbiota, endotoxemia, inflammation, and oxidative stress in patients with heart failure, left ventricular assist device, and transplant
Q90397281Hemocompatibility-related Adverse Events Following HeartMate II Left Ventricular Assist Device Implantation between Japan and United States
Q92625470Intramyocardial Injection of Mesenchymal Precursor Cells and Successful Temporary Weaning From Left Ventricular Assist Device Support in Patients With Advanced Heart Failure: A Randomized Clinical Trial
Q50087100Long-Acting Octreotide Reduces the Recurrence of Gastrointestinal Bleeding in Patients with a Continuous-Flow Left Ventricular Assist Device
Q88581991National Landscape of Unplanned 30-Day Readmissions in Patients With Left Ventricular Assist Device Implantation
Q57818806Omega-3 Therapy Is Associated With Reduced Gastrointestinal Bleeding in Patients With Continuous-Flow Left Ventricular Assist Device
Q92076256Omega-3 and hemocompatibility-related adverse events
Q90789242Optimal haemodynamics during left ventricular assist device support are associated with reduced haemocompatibility-related adverse events
Q38612227Pharmacotherapeutic Management of Gastrointestinal Bleeding in Patients with Continuous-Flow Left-Ventricular Assist Devices
Q40052734Prevalence of Cerebral Microbleeds in Patients With Continuous-Flow Left Ventricular Assist Devices
Q42340630Stop the LVAD bleeding
Q47124541Tumor necrosis factor-α levels and non-surgical bleeding in continuous-flow left ventricular assist devices

Search more.