MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation

scientific article published on 30 June 2013

MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NI.2648
P932PMC publication ID3740954
P698PubMed publication ID23812097
P5875ResearchGate publication ID243968090

P50authorPeiwen LuQ59175834
Eric VerdinQ37373521
P2093author name stringHyung W Lim
John R Teijaro
Michael B A Oldstone
Changchun Xiao
Hai Qi
Seung Goo Kang
Hyun Yong Jin
Wen-Hsien Liu
Daniel Fremgen
Jovan Shepherd
P2860cites workA vital role for interleukin-21 in the control of a chronic viral infectionQ42541944
Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistenceQ42937121
Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene.Q46011005
IL-21R on T cells is critical for sustained functionality and control of chronic viral infectionQ46697142
Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development.Q46721586
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.Q50736370
Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility.Q50903417
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.Q52126962
Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elementsQ57228054
Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosusQ61411628
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineagesQ24642180
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clustersQ24645192
miRiad roles for the miR-17-92 cluster in development and diseaseQ24646970
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytesQ24651802
The functions of animal microRNAsQ27860621
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiationQ28252247
Bcl6 mediates the development of T follicular helper cellsQ28252825
Restoring function in exhausted CD8 T cells during chronic viral infectionQ28289222
Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reactionQ28292732
A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunityQ28507088
microRNA functionsQ29547393
Follicular helper CD4 T cells (TFH)Q29615063
MicroRNA control in the immune system: basic principlesQ29618112
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanismQ33656121
IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responsesQ33656146
A fundamental role for interleukin-21 in the generation of T follicular helper cellsQ34792475
Viral persistence redirects CD4 T cell differentiation toward T follicular helper cellsQ34973705
Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiationQ35553324
Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cellsQ35607142
Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infectionQ36073682
Organ-specific selection of viral variants during chronic infectionQ36354968
Follicular helper T cells are required for systemic autoimmunityQ37234304
Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase.Q37453462
Physiological and pathological roles for microRNAs in the immune systemQ37680666
Development and characterization of IL-21-producing CD4+ T cellsQ38845667
IL-21 is required to control chronic viral infectionQ39328817
MicroRNA-17-92 significantly enhances radioresistance in human mantle cell lymphoma cellsQ39637411
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6Q42136332
P4510describes a project that usesImageQuantQ112270642
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
P304page(s)849-857
P577publication date2013-06-30
P1433published inNature ImmunologyQ1071725
P1476titleMicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation
P478volume14

Reverse relations

cites work (P2860)
Q46216142A Distinct Inhibitory Function for miR-18a in Th17 Cell Differentiation.
Q37197958A miR-155-Peli1-c-Rel pathway controls the generation and function of T follicular helper cells.
Q34517141A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production
Q35510446A p85α-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells
Q93274017Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells
Q34454614Antiviral B cell and T cell immunity in the lungs.
Q64935114Association between polymorphisms in the promoter region of miR-17-92 cluster and systemic lupus erythematosus in a Chinese population.
Q34985437CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement
Q34240220Complex interactions of transcription factors in mediating cytokine biology in T cells
Q47980819Control of T(FH) differentiation by a microRNA cluster
Q38159861Control of TFH cell numbers: why and how?
Q37338162Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.
Q37317118Cutting Edge: miR-17-92 Is Required for Both CD4 Th1 and T Follicular Helper Cell Responses during Viral Infection
Q42139003Designing Ago2-specific siRNA/shRNA to Avoid Competition with Endogenous miRNAs
Q36291392Differential Sensitivity of Target Genes to Translational Repression by miR-17~92.
Q55213325Differentially Expressed Genes in Osteomyelitis Induced by Staphylococcus aureus Infection.
Q58778275Effects of Major Epigenetic Factors on Systemic Lupus Erythematosus
Q49776114Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease
Q30300786Engineering control into medicine
Q39142245Epigenetic Alterations in Cellular Immunity: New Insights into Autoimmune Diseases
Q58801888Follicular Helper T Cells in Systemic Lupus Erythematosus
Q28067781Follicular Helper T Cells in Systemic Lupus Erythematosus: Why Should They Be Considered as Interesting Therapeutic Targets?
Q38154470Follicular T-helper cells: controlled localization and cellular interactions
Q38812644Follicular helper T cell in immunity and autoimmunity
Q35242659Follicular helper T cell signature in type 1 diabetes
Q38917576Functional RNAs control T follicular helper cells
Q36101314Functional interactions among members of the miR-17-92 cluster in lymphocyte development, differentiation and malignant transformation
Q38237119Immuno-miRs: critical regulators of T-cell development, function and ageing
Q39108760Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies.
Q40506554Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation
Q28079717Innate and Adaptive Immune Regulation During Chronic Viral Infections
Q37617212Insights into the role of follicular helper T cells in autoimmunity
Q37300464Japanese Macaque Rhadinovirus Encodes a Viral MicroRNA Mimic of the miR-17 Family
Q26825249Life of T follicular helper cells
Q26825457MYC and the art of microRNA maintenance
Q59355805MiR-18a and miR-17 are positively correlated with circulating PD-1ICOS follicular helper T cells after hepatitis B vaccination in a chinese population
Q26852975MicroRNA regulation of lymphocyte tolerance and autoimmunity
Q27026073MicroRNA regulation of the germinal center response
Q46425558MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation
Q35197004MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres
Q52659696MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice.
Q55283218MicroRNA-mediated Regulation of the Development and Functions of Follicular Helper T cells.
Q52688461MicroRNA-mediated dynamic control of mucosal immunity.
Q37693699MicroRNA-mediated regulation of T helper cell differentiation and plasticity.
Q38819277MicroRNAs as regulatory elements in immune system logic
Q35134358MicroRNAs in hematopoietic development
Q35135542MicroRNAs: new players in IBD.
Q58556221Molecular Control of Follicular Helper T cell Development and Differentiation
Q41464447Mycophenolic acid upregulates miR-142-3P/5P and miR-146a in lupus CD4+T cells.
Q36605149Nanogel-based pneumococcal surface protein A nasal vaccine induces microRNA-associated Th17 cell responses with neutralizing antibodies against Streptococcus pneumoniae in macaques
Q39016144New insights into the immunopathogenesis of systemic lupus erythematosus.
Q92062346Non-Coding RNAs in CD4+ T Cells: New Insights Into the Pathogenesis of Systemic Lupus Erythematosus
Q38212814Noncoding RNA and its associated proteins as regulatory elements of the immune system.
Q38561971Noncoding RNAs and chronic inflammation: Micro-managing the fire within.
Q35439757PD-1 deficiency enhances humoral immunity of malaria infection treatment vaccine
Q38664551PHLPP phosphatases as a therapeutic target in insulin resistance-related diseases
Q36220467Phenotypic Tfh development promoted by CXCR5-controlled re-localization and IL-6 from radiation-resistant cells
Q59354521Posttranscriptional Gene Regulation of T Follicular Helper Cells by RNA-Binding Proteins and microRNAs
Q88446289Posttranscriptional regulation of T helper cell fate decisions
Q27003385Progress and challenge of microRNA research in immunity
Q92423986RNA Nanotechnology-Mediated Cancer Immunotherapy
Q57175036Regulation of T Follicular Helper Cells in Islet Autoimmunity
Q34416635Regulatory T cells in B cell follicles
Q46262418Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells
Q48118503Responsiveness of Developing T Cells to IL-7 Signals Is Sustained by miR-17∼92.
Q38264816T follicular helper cell differentiation, function, and roles in disease
Q38940412T follicular helper cells in space-time.
Q38682344T follicular helper cells, T follicular regulatory cells and autoimmunity.
Q27014065Targeting microRNAs for immunomodulation
Q38530613The E3 ligase Itch in immune regulation and beyond.
Q34901817The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells
Q54987756The Janus Face of Follicular T Helper Cells in Chronic Viral Infections.
Q35930798The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity.
Q104135052The transcription factor TAL1 and miR-17-92 create a regulatory loop in hematopoiesis
Q38228101Therapeutic targeting of microRNAs: current status and future challenges
Q89519024Three paralogous clusters of the miR-17~92 family of microRNAs restrain IL-12-mediated immune defense
Q35064355Transcriptional and epigenetic networks of helper T and innate lymphoid cells.
Q39163678Transcriptional and epigenetic regulation of follicular T-helper cells and their role in autoimmunity
Q36466905Transcriptome-wide high-throughput deep m(6)A-seq reveals unique differential m(6)A methylation patterns between three organs in Arabidopsis thaliana.
Q36339696Transfection of microRNA Mimics Should Be Used with Caution.
Q34979730Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.
Q40537683mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.
Q42631760miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation
Q33556109miR-17-92 cluster targets phosphatase and tensin homology and Ikaros Family Zinc Finger 4 to promote TH17-mediated inflammation
Q37534350miR-17∼92 family clusters control iNKT cell ontogenesis via modulation of TGF-β signaling
Q35402694miR-18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells
Q39747635miR-20a inhibits TCR-mediated signaling and cytokine production in human naïve CD4+ T cells
Q36569356miR-23∼27∼24 clusters control effector T cell differentiation and function
Q36176908miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity
Q26768556miRNAs as new molecular insights into inflammatory bowel disease: Crucial regulators in autoimmunity and inflammation
Q28083028miRNAs in the Pathogenesis of Systemic Lupus Erythematosus
Q35780533microRNA-17-5p Modulates Bacille Calmette-Guerin Growth in RAW264.7 Cells by Targeting ULK1.
Q34375186microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells.

Search more.