| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2003PNAS..10013650S |
| P356 | DOI | 10.1073/PNAS.2232515100 |
| P953 | full work available at URL | https://europepmc.org/articles/pmc263868?pdf=render |
| https://europepmc.org/articles/PMC263868 | ||
| https://europepmc.org/articles/PMC263868?pdf=render | ||
| https://doi.org/10.1073/pnas.2232515100 | ||
| https://pnas.org/doi/pdf/10.1073/pnas.2232515100 | ||
| P932 | PMC publication ID | 263868 |
| P698 | PubMed publication ID | 14595022 |
| P5875 | ResearchGate publication ID | 9028876 |
| P50 | author | Patrice D. Smith | Q52147917 |
| David S Park | Q60560240 | ||
| Serge Przedborski | Q67180857 | ||
| Vernice Jackson-Lewis | Q67189596 | ||
| P2093 | author name string | Hymie Anisman | |
| Shawn Hayley | |||
| Kelly L. Jordan-Sciutto | |||
| Ruth S. Slack | |||
| Matthew P. Mount | |||
| Michael J. O'Hare | |||
| Steven Callaghan | |||
| Stephen J. Crocker | |||
| P2860 | cites work | Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons | Q22010952 |
| Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity | Q24297369 | ||
| p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5 | Q24320432 | ||
| The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2 | Q24561705 | ||
| Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration | Q28140796 | ||
| Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology | Q28199047 | ||
| Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality | Q28302232 | ||
| The Cdk5-p35 kinase associates with the Golgi apparatus and regulates membrane traffic | Q28366369 | ||
| Cdk5-Mediated Inhibition of the Protective Effects of Transcription Factor MEF2 in Neurotoxicity-Induced Apoptosis | Q28571515 | ||
| The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation | Q28577018 | ||
| Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat | Q28583944 | ||
| Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death | Q28587075 | ||
| p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment | Q28589437 | ||
| Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions | Q28591963 | ||
| Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease | Q28594269 | ||
| Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth | Q28594587 | ||
| Cdk5 phosphorylates p53 and regulates its activity | Q28609768 | ||
| Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity | Q30469610 | ||
| Thio- and oxoflavopiridols, cyclin-dependent kinase 1-selective inhibitors: synthesis and biological effects. | Q31526877 | ||
| The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety | Q32133943 | ||
| E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3. | Q33180163 | ||
| c-Jun mediates axotomy-induced dopamine neuron death in vivo | Q33949411 | ||
| Pharmacological inhibitors of cyclin-dependent kinases | Q34866778 | ||
| Cellular mechanisms of striatum-dependent behavioral plasticity and drug addiction | Q34991351 | ||
| Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease | Q35082309 | ||
| Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5 | Q35084361 | ||
| Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents | Q36255573 | ||
| Neurotransmitters and neuromodulators in the basal ganglia | Q36586002 | ||
| Cyclin-dependent kinases as a therapeutic target for stroke. | Q37445826 | ||
| D1-Receptor-related priming is attenuated by antisense-meditated 'knockdown' of fosB expression. | Q38338409 | ||
| Dendritic release of dopamine in the substantia nigra | Q40123417 | ||
| Cyclins and their associated cyclin-dependent kinases in the human cell cycle | Q40727258 | ||
| Induction of Cyclin B and H1 Kinase Activity in Apoptotic PC12 Cells | Q41317210 | ||
| Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease. | Q41863368 | ||
| Cortical and brainstem-type Lewy bodies are immunoreactive for the cyclin-dependent kinase 5 | Q42123777 | ||
| Amphetamine induces hypermotility in MPTP-lesioned mice. | Q42435220 | ||
| Increased expression of cyclin-dependent kinase 5 in induced apoptotic neuron death in rat substantia nigra | Q42442815 | ||
| Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model. | Q42524390 | ||
| Chronic alterations in dopaminergic neurotransmission produce a persistent elevation of deltaFosB-like protein(s) in both the rodent and primate striatum | Q42555260 | ||
| Cdk2 kinase phosphorylates serine 315 of human p53 in vitro. | Q42826075 | ||
| Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? | Q43507724 | ||
| Expression of cyclin-dependent kinase 5 and its activator p35 in models of induced apoptotic death in neurons of the substantia nigra in vivo | Q43645455 | ||
| Ectopic expression of cell cycle markers in models of induced programmed cell death in dopamine neurons of the rat substantia nigra pars compacta | Q44264442 | ||
| Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1. | Q44376552 | ||
| Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease. | Q44451960 | ||
| A novel disruption of cortical development in p35(-/-) mice distinct from reeler | Q47996554 | ||
| Dopamine in dendrites of substantia nigra neurons: suggestions for a role in dendritic terminals. | Q48479954 | ||
| p35nck5a and cyclin-dependent kinase 5 colocalize in Lewy bodies of brains with Parkinson's disease. | Q48651496 | ||
| Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments. | Q53317292 | ||
| The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity | Q59097192 | ||
| Induction and modulation of cerebellar granule neuron death by E2F-1 | Q64380700 | ||
| Neurofilaments in health and disease | Q64869492 | ||
| Evidence that L-dopa-induced rotational behavior is dependent on both striatal and nigral mechanisms | Q69754343 | ||
| Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death | Q72247935 | ||
| Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25 | Q73626649 | ||
| Cdk5/p25(nck5a) interaction with synaptic proteins in bovine brain | Q73748003 | ||
| Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons | Q73863849 | ||
| Expression and activity of cyclin-dependent kinase 5/p35 in adult rat peripheral nervous system | Q77613549 | ||
| Estimation of nuclear population from microtome sections | Q82126847 | ||
| P433 | issue | 23 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Parkinson's disease | Q11085 |
| dopamine | Q170304 | ||
| dopaminergic neuron | Q66591220 | ||
| P304 | page(s) | 13650-13655 | |
| P577 | publication date | 2003-10-31 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease | |
| P478 | volume | 100 |
| Q92479201 | A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria |
| Q37243137 | AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease. |
| Q37336692 | ATP-noncompetitive inhibitors of CDK-cyclin complexes. |
| Q28579004 | Activation of ataxia telangiectasia muted under experimental models and human Parkinson's disease |
| Q28394023 | Acupuncture enhances the synaptic dopamine availability to improve motor function in a mouse model of Parkinson's disease |
| Q54379908 | Alterations of cyclin dependent kinase 5 expression and phosphorylation in amyloid precursor protein (APP)-transfected PC12 cells. |
| Q37053631 | An unusual member of the Cdk family: Cdk5. |
| Q48103083 | Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons |
| Q36789912 | Axonal Segregation and Role of the Vesicular Glutamate Transporter VGLUT3 in Serotonin Neurons |
| Q24322908 | BAG5 inhibits parkin and enhances dopaminergic neuron degeneration |
| Q33911733 | CDK5-mediated phosphorylation of XBP1s contributes to its nuclear translocation and activation in MPP+-induced Parkinson's disease model |
| Q47739915 | Calcium dysregulation and Cdk5-ATM pathway involved in a mouse model of fragile X-associated tremor/ataxia syndrome |
| Q46890595 | Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2. |
| Q40162565 | Cdc25A Is a Critical Mediator of Ischemic Neuronal Death In Vitro and In Vivo |
| Q55177664 | Cdk5 Inhibitory Peptide Prevents Loss of Dopaminergic Neurons and Alleviates Behavioral Changes in an MPTP Induced Parkinson's Disease Mouse Model. |
| Q33687591 | Cdk5 activity in the brain - multiple paths of regulation |
| Q38587949 | Cdk5 at crossroads of protein oligomerization in neurodegenerative diseases: facts and hypotheses |
| Q38213140 | Cdk5 regulates multiple cellular events in neural development, function and disease. |
| Q40801428 | Cdk5-Dependent Activation of Neuronal Inflammasomes in Parkinson's Disease. |
| Q28115581 | Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease |
| Q48788900 | Cdk5/p35 is required for motor coordination and cerebellar plasticity. |
| Q37877809 | Cdk5: mediator of neuronal development, death and the response to DNA damage |
| Q24299163 | Cdk5: multitasking between physiological and pathological conditions |
| Q37879917 | Cell cycle reactivation in mature neurons: a link with brain plasticity, neuronal injury and neurodegenerative diseases? |
| Q37376117 | Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps |
| Q26740364 | Chaperone-Mediated Autophagy and Mitochondrial Homeostasis in Parkinson's Disease |
| Q48678812 | Cognitive function in health and disease: the role of epigenetic mechanisms. |
| Q97519999 | Collapsin Response Mediator Proteins: Their Biological Functions and Pathophysiology in Neuronal Development and Regeneration |
| Q39909871 | Combined kinase inhibition modulates parkin inactivation. |
| Q39819662 | Commitment of 1-methyl-4-phenylpyrinidinium ion-induced neuronal cell death by proteasome-mediated degradation of p35 cyclin-dependent kinase 5 activator |
| Q64098935 | Computational Simulations Identified Two Candidate Inhibitors of Cdk5/p25 to Abrogate Tau-associated Neurological Disorders |
| Q36671551 | Connecting cell-cycle activation to neurodegeneration in Drosophila. |
| Q46046558 | Curcumin Ameliorates Neuroinflammation, Neurodegeneration, and Memory Deficits in p25 Transgenic Mouse Model that Bears Hallmarks of Alzheimer's Disease. |
| Q34249306 | Cyclin-dependent kinase 5 activity regulates pain signaling. |
| Q37402773 | Cyclin-dependent kinase 5 inhibitors: inhibition of dopamine transporter activity |
| Q57834817 | Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis |
| Q46486132 | Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2. |
| Q28594634 | Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum |
| Q36446511 | Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. |
| Q38035191 | Defective autophagy in Parkinson's disease: role of oxidative stress. |
| Q46800741 | Delayed combinatorial treatment with flavopiridol and minocycline provides longer term protection for neuronal soma but not dendrites following global ischemia. |
| Q28475093 | Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models |
| Q34028507 | Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity |
| Q28576044 | Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death |
| Q21135535 | Distinct cerebrospinal fluid proteomes differentiate post-treatment lyme disease from chronic fatigue syndrome |
| Q44045827 | Docking and 3D-QSAR modeling of cyclin-dependent kinase 5/p25 inhibitors |
| Q46202882 | Dopamine induces supernumerary centrosomes and subsequent cell death through Cdk2 up-regulation in dopaminergic neuronal cells |
| Q39933436 | Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5. |
| Q27304699 | Efficient and biologically relevant consensus strategy for Parkinson's disease gene prioritization. |
| Q40494780 | Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress |
| Q33637667 | Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo. |
| Q47733092 | Explaining the inhibition of cyclin-dependent kinase 5 by peptides derived from p25 with molecular dynamics simulations and MM-PBSA. |
| Q60695461 | Exploring the Role of Autophagy in the Pathogenesis of Rotenone-induced Toxicity |
| Q43447647 | Extracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro. |
| Q52723921 | Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death. |
| Q28593258 | Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. |
| Q35322482 | Identification of a set of endogenous reference genes for miRNA expression studies in Parkinson's disease blood samples |
| Q39836825 | Identification of non-muscle myosin heavy chain as a substrate for Cdk5 and tool for drug screening |
| Q35000764 | Identification of the sites of tau hyperphosphorylation and activation of tau kinases in synucleinopathies and Alzheimer's diseases |
| Q37238059 | Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation |
| Q24315046 | Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1 |
| Q23919642 | Indirubins deplete striatal monoamines in the intact and MPTP-treated mouse brain and block kainate-induced striatal astrogliosis |
| Q54977089 | Inducible Knockout of the Cyclin-Dependent Kinase 5 Activator p35 Alters Hippocampal Spatial Coding and Neuronal Excitability. |
| Q46557913 | Inhibition of multiple pathways accounts for the antiapoptotic effects of flavopiridol on potassium withdrawal-induced apoptosis in neurons |
| Q46961856 | Inhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease |
| Q38684570 | Insights into Ligand-Protein Binding from Local Mechanical Response. |
| Q45068627 | Interaction of Cdk5 and cAMP/PKA Signaling in the Mediation of Neuropsychiatric and Neurodegenerative Diseases |
| Q34936423 | Intracellular signalling pathways in dopamine cell death and axonal degeneration. |
| Q28383558 | Involvement of aberrant cyclin-dependent kinase 5/p25 activity in experimental traumatic brain injury |
| Q36588397 | Involvement of calpain activation in neurodegenerative processes. |
| Q34369428 | Involvement of calpain/p35-p25/Cdk5/NMDAR signaling pathway in glutamate-induced neurotoxicity in cultured rat retinal neurons |
| Q53575010 | Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons. |
| Q35675127 | Korean Red Ginseng protects dopaminergic neurons by suppressing the cleavage of p35 to p25 in a Parkinson's disease mouse model. |
| Q89288970 | Malfunctioning of Chaperone-Mediated Autophagy in Parkinson's Disease: Feats, Constraints, and Flaws of Modulators |
| Q51766677 | Mechanism of CDK5 activation revealed by steered molecular dynamics simulations and energy calculations. |
| Q37082050 | Mechanisms of neurodegeneration in idiopathic Parkinson's disease |
| Q36777303 | Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation. |
| Q42580316 | Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD. |
| Q49015269 | Mitochondrial β-amyloid in Alzheimer's disease. |
| Q28478957 | Modularity in protein complex and drug interactions reveals new polypharmacological properties |
| Q54441914 | Molecular dynamic simulations give insight into the mechanism of binding between 2-aminothiazole inhibitors and CDK5. |
| Q79280859 | Molecular dynamics simulations on the inhibition of cyclin-dependent kinases 2 and 5 in the presence of activators |
| Q38234170 | Molecular mechanisms of dopaminergic subset specification: fundamental aspects and clinical perspectives. |
| Q37462203 | Molecular pathology of Lewy body diseases. |
| Q34047944 | Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo. |
| Q34486383 | Mutations and novel polymorphisms in coding regions and UTRs of CDK5R1 and OMG genes in patients with non-syndromic mental retardation |
| Q41966927 | Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease |
| Q28082792 | Neuroprotective Mechanisms Mediated by CDK5 Inhibition |
| Q33733724 | No difference in kinetics of tau or histone phosphorylation by CDK5/p25 versus CDK5/p35 in vitro |
| Q44168907 | PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress |
| Q30239814 | Parkinson's Disease and Cognitive Impairment |
| Q64083021 | Parkinson's Disease is Associated with Dysregulations of a Dopamine-Modulated Gene Network Relevant to Sleep and Affective Neurobehaviors in the Striatum |
| Q37948585 | Parkinson's disease and cancer: two wars, one front |
| Q54276344 | Parkinson's disease-associated PINK1 G309D mutation increases abnormal phosphorylation of Tau. |
| Q33797449 | Parkinson's disease-implicated kinases in the brain; insights into disease pathogenesis |
| Q36337052 | Peptide TFP5/TP5 derived from Cdk5 activator P35 provides neuroprotection in the MPTP model of Parkinson's disease |
| Q28592513 | Perinatal abrogation of Cdk5 expression in brain results in neuronal migration defects |
| Q80751120 | Peroxiredoxin-2 links Cdk5 to neurodegeneration |
| Q36850316 | Perturbation of transcription factor Nur77 expression mediated by myocyte enhancer factor 2D (MEF2D) regulates dopaminergic neuron loss in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). |
| Q40165778 | Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation. |
| Q38036233 | Programmed cell death in Parkinson's disease |
| Q24314837 | Protective effect against Parkinson's disease-related insults through the activation of XBP1 |
| Q37753509 | Rational therapeutic approaches to progressive supranuclear palsy |
| Q35129037 | Regulation of Sox6 by cyclin dependent kinase 5 in brain |
| Q37941527 | Role of cell cycle re-entry in neurons: a common apoptotic mechanism of neuronal cell death |
| Q24612303 | S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptide |
| Q39330967 | S-nitrosylation of Cdk5: potential implications in amyloid-β-related neurotoxicity in Alzheimer disease |
| Q44360675 | Selective neuroprotective effects of the S18Y polymorphic variant of UCH-L1 in the dopaminergic system. |
| Q34651981 | Selectivity and potency of cyclin-dependent kinase inhibitors |
| Q37863144 | Silencing of CDK5 as potential therapy for Alzheimer's disease |
| Q24628256 | Silencing of CDK5 reduces neurofibrillary tangles in transgenic alzheimer's mice |
| Q37294815 | Similar cation channels mediate protection from cerebellar exitotoxicity by exercise and inheritance. |
| Q45971854 | Specific inhibition of p25/Cdk5 activity by the Cdk5 inhibitory peptide reduces neurodegeneration in vivo. |
| Q34706737 | Structure-activity relationship study of 2,4-diaminothiazoles as Cdk5/p25 kinase inhibitors |
| Q51181955 | Study of the inhibition of cyclin-dependent kinases with roscovitine and indirubin-3'-oxime from molecular dynamics simulations. |
| Q38940963 | Sumoylation of p35 modulates p35/cyclin-dependent kinase (Cdk) 5 complex activity |
| Q37288349 | TFP5 prevents 1-methyl-4-phenyl pyridine ion-induced neurotoxicity in mouse cortical neurons |
| Q34549221 | TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice |
| Q26747606 | TFP5/TP5 peptide provides neuroprotection in the MPTP model of Parkinson's disease |
| Q35767929 | TNIP1, a retinoic acid receptor corepressor and A20-binding inhibitor of NF-κB, distributes to both nuclear and cytoplasmic locations |
| Q26827580 | Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitors |
| Q33308313 | The 3' untranslated region of human Cyclin-Dependent Kinase 5 Regulatory subunit 1 contains regulatory elements affecting transcript stability |
| Q39767094 | The Cdk5 kinase downregulates ATP-gated ionotropic P2X3 receptor function via serine phosphorylation |
| Q42500271 | The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin. |
| Q34549505 | The calcium-binding protein EFhd2 modulates synapse formation in vitro and is linked to human dementia. |
| Q46747405 | The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy |
| Q35652312 | The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease |
| Q39281423 | The role of Ca2+ signaling in Parkinson's disease |
| Q48196301 | The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death |
| Q33916147 | The role of miR-103 and miR-107 in regulation of CDK5R1 expression and in cellular migration |
| Q36812366 | Ubiquitin C-terminal hydrolase L1 (UCH-L1) acts as a novel potentiator of cyclin-dependent kinases to enhance cell proliferation independently of its hydrolase activity |
| Q27931708 | Yeast Gcn4p stabilization is initiated by the dissociation of the nuclear Pho85p/Pcl5p complex. |
| Q34899098 | Zebrafish Rohon-Beard neuron development: cdk5 in the midst |
| Q58695469 | Zinc induces CDK5 activation and neuronal death through CDK5-Tyr15 phosphorylation in ischemic stroke |
| Q28070292 | c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson's Disease |
| Q36471210 | p10, the N-terminal domain of p35, protects against CDK5/p25-induced neurotoxicity |
| Q40397437 | p53, Apaf-1, caspase-3, and -9 are dispensable for Cdk5 activation during cell death |
| Q93049755 | α-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1 |
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