RecA protein promotes the regression of stalled replication forks in vitro

scientific article published on July 2001

RecA protein promotes the regression of stalled replication forks in vitro is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2001PNAS...98.8211R
P356DOI10.1073/PNAS.131022698
P932PMC publication ID37423
P698PubMed publication ID11459955
P5875ResearchGate publication ID11881969

P2093author name stringM M Cox
R B Inman
M E Robu
P2860cites workInitiation of genetic recombination and recombination-dependent replicationQ28141289
On the role of ATP hydrolysis in RecA protein-mediated DNA strand exchange. III. Unidirectional branch migration and extensive hybrid DNA formationQ28246178
The importance of repairing stalled replication forksQ29614220
A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragmentsQ29618189
Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambdaQ29619755
Differential replication of a single, UV-induced lesion in the leading or lagging strand by a human cell extract: fork uncoupling or gap formationQ33636561
Recombinational DNA repair in bacteria and the RecA proteinQ33743842
Replication fork arrest and DNA recombinationQ33885416
PriA-directed replication fork restart in Escherichia coliQ33885421
DNA double-strand breaks caused by replication arrestQ33886030
The translocating RecBCD enzyme stimulates recombination by directing RecA protein onto ssDNA in a chi-regulated mannerQ34433258
DNA-strand exchange promoted by RecA protein in the absence of ATP: implications for the mechanism of energy transduction in protein-promoted nucleic acid transactionsQ34446753
The RecBC enzyme loads RecA protein onto ssDNA asymmetrically and independently of chi, resulting in constitutive recombination activationQ35193453
Computer-assisted DNA length measurements from electron micrographs with special reference to partial denaturation mappingQ35494044
Homologous pairing in genetic recombination: formation of D loops by combined action of recA protein and a helix-destabilizing proteinQ36388142
Purified Escherichia coli recA protein catalyzes homologous pairing of superhelical DNA and single-stranded fragmentsQ37326507
Stable DNA heteroduplex formation catalyzed by the Escherichia coli RecA protein in the absence of ATP hydrolysisQ37655391
Analysis of DNA replication forks encountering a pyrimidine dimer in the template to the leading strandQ38323661
Function of nucleoside triphosphate and polynucleotide in Escherichia coli recA protein-directed cleavage of phage lambda repressorQ38356140
Visualisation of plasmid replication intermediates containing reversed forksQ39541952
Why does RecA protein hydrolyse ATP?Q40682056
In vitro reconstitution of homologous recombination reactionsQ40733589
RecA as a motor protein. Testing models for the role of ATP hydrolysis in DNA strand exchangeQ43744290
Positive torsional strain causes the formation of a four-way junction at replication forksQ46674361
DNA strand exchange promoted by RecA K72R. Two reaction phases with different Mg2+ requirementsQ47854190
On the mechanism of RecA-mediated repair of double-strand breaks: no role for four-strand DNA pairing intermediatesQ47862748
Two binding modes in Escherichia coli single strand binding protein-single stranded DNA complexes. Modulation by NaCl concentration.Q52673770
Evidence for the coupling of ATP hydrolysis to the final (extension) phase of RecA protein-mediated DNA strand exchange.Q54592049
An interaction between the Escherichia coli RecF and RecR proteins dependent on ATP and double-stranded DNA.Q54598042
Alteration of the nucleoside triphosphate (NTP) catalytic domain within Escherichia coli recA protein attenuates NTP hydrolysis but not joint molecule formation.Q54663379
On the role of ATP hydrolysis in RecA protein-mediated DNA strand exchange. II. Four-strand exchanges.Q54674604
Large-scale overproduction and rapid purification of the Escherichia coli ssb gene product. Expression of the ssb gene under lambda PL control.Q54785144
Mechanism of E. coli RecA protein directed strand exchanges in post-replication repair of DNAQ58028717
RuvABC-dependent double-strand breaks in dnaBts mutants require recAQ64388328
ATP hydrolysis and DNA binding by the Escherichia coli RecF proteinQ64388887
The direction of RecA protein assembly onto single strand DNA is the same as the direction of strand assimilation during strand exchangeQ64390477
A model for replication repair in mammalian cellsQ67440139
On the role of ATP hydrolysis in RecA protein-mediated DNA strand exchange. I. Bypassing a short heterologous insert in one DNA substrateQ68236652
Exchange of recA protein between adjacent recA protein-single-stranded DNA complexesQ69612027
Partial denaturation of thymine- and 5-bromouracil-containing λ DNA in alkaliQ71520645
RecA protein filaments: end-dependent dissociation from ssDNA and stabilization by RecO and RecR proteinsQ73107375
Modulation of RNA polymerase by (p)ppGpp reveals a RecG-dependent mechanism for replication fork progressionQ73707166
Recombinational DNA repair: the RecF and RecR proteins limit the extension of RecA filaments beyond single-strand DNA gapsQ73863469
Resolution of holliday junctions by RuvABC prevents dimer formation in rep mutants and UV-irradiated cellsQ74130012
RuvAB acts at arrested replication forksQ77550034
Differential rates of NTP hydrolysis by the mutant [S69G]RecA protein. Evidence for a coupling of NTP turnover to DNA strand exchangeQ78207892
P4510describes a project that usesImageQuantQ112270642
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectreplication fork processingQ14883729
P304page(s)8211-8218
P577publication date2001-07-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleRecA protein promotes the regression of stalled replication forks in vitro
P478volume98

Reverse relations

cites work (P2860)
Q92646993A 5'-to-3' strand exchange polarity is intrinsic to RecA nucleoprotein filaments in the absence of ATP hydrolysis
Q54516795A Tetramer–Octamer Equilibrium in Mycobacterium leprae and Escherichia coli RuvA by Analytical Ultracentrifugation
Q41117294A defect in homologous recombination leads to increased translesion synthesis in E. coli.
Q33944015A transcriptional response to replication status mediated by the conserved bacterial replication protein DnaA.
Q38290716ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair
Q74499929Action of RuvAB at replication fork structures
Q40175940Active displacement of RecA filaments by UvrD translocase activity.
Q27931955An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination.
Q24812864Bacillus subtilis RecU Holliday-junction resolvase modulates RecA activities
Q38855351Changes in the tension in dsDNA alter the conformation of RecA bound to dsDNA-RecA filaments
Q37168320Characterization of the ATPase activity of RecG and RuvAB proteins on model fork structures reveals insight into stalled DNA replication fork repair
Q53661726Cleavage of model replication forks by fission yeast Mus81-Eme1 and budding yeast Mus81-Mms4.
Q36438748Cleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpoint
Q46983567Complementation of one RecA protein point mutation by another. Evidence for trans catalysis of ATP hydrolysis
Q34723611Cooperation of RAD51 and RAD54 in regression of a model replication fork
Q24630816DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombination
Q42426538Defective dissociation of a "slow" RecA mutant protein imparts an Escherichia coli growth defect
Q35037441Defending genome integrity during S-phase: putative roles for RecQ helicases and topoisomerase III.
Q33636060Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats
Q54549876Direct rescue of stalled DNA replication forks via the combined action of PriA and RecG helicase activities.
Q44199583DnaB drives DNA branch migration and dislodges proteins while encircling two DNA strands.
Q92266072Elucidating the functional role of Mycobacterium smegmatis recX in stress response
Q37044564Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA.
Q24314570FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51
Q37010489Fate of the replisome following arrest by UV-induced DNA damage in Escherichia coli
Q37168603Fork regression is an active helicase-driven pathway in bacteriophage T4
Q54522966Functional dissection of the Schizosaccharomyces pombe Holliday junction resolvase Ydc2: in vivo role in mitochondrial DNA maintenance.
Q34762160Genome stability and the processing of damaged replication forks by RecG.
Q24631768Historical overview: searching for replication help in all of the rec places
Q37574376Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase
Q38223677Homologous recombination as a replication fork escort: fork-protection and recovery.
Q35738776Interplay between DNA replication, recombination and repair based on the structure of RecG helicase
Q33761161Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance.
Q36710001Motoring along with the bacterial RecA protein
Q35870700Multiple pathways process stalled replication forks
Q38297065Mycobacterium tuberculosis RecG protein but not RuvAB or RecA protein is efficient at remodeling the stalled replication forks: implications for multiple mechanisms of replication restart in mycobacteria
Q35561953Organelle DNA rearrangement mapping reveals U-turn-like inversions as a major source of genomic instability in Arabidopsis and humans
Q24797344Organized unidirectional waves of ATP hydrolysis within a RecA filament
Q44454296Participation of DNA polymerase II in the increased precise excision of Tn10.
Q37788950Pathways of mammalian replication fork restart.
Q28541496Phage ORF family recombinases: conservation of activities and involvement of the central channel in DNA binding
Q33855074Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity
Q37802636RAD18 lives a double life: Its implication in DNA double-strand break repair
Q42428356RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.
Q57753904RPA and RAD51: fork reversal, fork protection, and genome stability
Q36881719RecA-mediated SOS induction requires an extended filament conformation but no ATP hydrolysis
Q37014705RecG interacts directly with SSB: implications for stalled replication fork regression
Q34994566RecQ helicases and cellular responses to DNA damage
Q34444668Recombination and replication.
Q33962242Recombinational repair and restart of damaged replication forks.
Q49836835Reconstituting the 4-Strand DNA Strand Exchange
Q34317367Regression of replication forks stalled by leading-strand template damage: I. Both RecG and RuvAB catalyze regression, but RuvC cleaves the holliday junctions formed by RecG preferentially
Q34317373Regression of replication forks stalled by leading-strand template damage: II. Regression by RecA is inhibited by SSB
Q41831376Rep and PriA helicase activities prevent RecA from provoking unnecessary recombination during replication fork repair
Q57753866Replication Fork Breakage and Restart in Escherichia coli
Q35914188Replication Restart after Replication-Transcription Conflicts Requires RecA in Bacillus subtilis
Q50866409Replication arrest is a major threat to growth at low temperature in Antarctic Pseudomonas syringae Lz4W.
Q37465851Replication fork reversal and the maintenance of genome stability
Q54545064Replication fork reversal in DNA polymerase III mutants of Escherichia coli: a role for the beta clamp.
Q54442566Replication fork reversal occurs spontaneously after digestion but is constrained in supercoiled domains.
Q43944895Replication restart in UV-irradiated Escherichia coli involving pols II, III, V, PriA, RecA and RecFOR proteins
Q26859667Rescuing stalled or damaged replication forks
Q37521268Role of the Escherichia coli RecQ DNA helicase in SOS signaling and genome stabilization at stalled replication forks.
Q34410893RuvAB is essential for replication forks reversal in certain replication mutants.
Q30008790SSB and the RecG DNA helicase: an intimate association to rescue a stalled replication fork
Q38346395Situational repair of replication forks: roles of RecG and RecA proteins
Q33796363Spontaneous DNA breakage in single living Escherichia coli cells
Q33754225Srs2: the "Odd-Job Man" in DNA repair
Q38860416Stalled replication fork rescue requires a novel DNA helicase
Q36272177Structure and mechanism of Escherichia coli RecA ATPase
Q54540761Substrate specificity of RusA resolvase reveals the DNA structures targeted by RuvAB and RecG in vivo.
Q33559373Supercoiling, knotting and replication fork reversal in partially replicated plasmids
Q45079267Suppression of repeat-mediated gross mitochondrial genome rearrangements by RecA in the moss Physcomitrella patens
Q35562059Suppression of the E. coli SOS response by dNTP pool changes
Q38887164Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors.
Q39392254Template-switching during replication fork repair in bacteria
Q35550606The Bacterial RecA Protein as a Motor Protein
Q54463698The Bloom's syndrome helicase can promote the regression of a model replication fork.
Q88950020The Clash of Macromolecular Titans: Replication-Transcription Conflicts in Bacteria
Q39698943The RdgC protein of Escherichia coli binds DNA and counters a toxic effect of RecFOR in strains lacking the replication restart protein PriA.
Q33959536The RecA proteins of Deinococcus radiodurans and Escherichia coli promote DNA strand exchange via inverse pathways
Q42123307The RuvAB branch migration translocase and RecU Holliday junction resolvase are required for double-stranded DNA break repair in Bacillus subtilis
Q93185974The SOS system: A complex and tightly regulated response to DNA damage
Q35013053The nonmutagenic repair of broken replication forks via recombination
Q42599202The role of the SAP motif in promoting Holliday junction binding and resolution by SpCCE1.
Q30842959Threshold effect of growth rate on population variability of Escherichia coli cell lengths
Q64387291Tools To Live By: Bacterial DNA Structures Illuminate Cancer
Q35607006Topological locking restrains replication fork reversal
Q24792121Torque-limited RecA polymerization on dsDNA.
Q34165028Uracil in DNA--occurrence, consequences and repair
Q34644150Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair

Search more.