| P2093 | author name string | Alexander G Robling | |
| | Charles H Turner | |
| P2860 | cites work | Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST) | Q24290838 |
| | SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor | Q24303393 |
| | Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease | Q24679575 |
| | NMR structure of the Wnt modulator protein Sclerostin | Q27653504 |
| | Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism | Q28114789 |
| | LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development | Q28206790 |
| | Spatial distribution of Bax and Bcl-2 in osteocytes after bone fatigue: complementary roles in bone remodeling regulation? | Q28217341 |
| | The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment | Q28247505 |
| | Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin | Q28261537 |
| | Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis | Q28507090 |
| | Osteocytes use estrogen receptor alpha to respond to strain but their ERalpha content is regulated by estrogen | Q28582753 |
| | The P2X7 nucleotide receptor mediates skeletal mechanotransduction | Q28586177 |
| | Shorter, more frequent mechanical loading sessions enhance bone mass | Q30807543 |
| | Improved bone structure and strength after long-term mechanical loading is greatest if loading is separated into short bouts | Q31101746 |
| | Osteoclastogenesis inhibitory factor/osteoprotegerin reduced bone loss induced by mechanical unloading | Q31129878 |
| | Optimization of bone growth and remodeling in response to loading in tapered mammalian limbs | Q31153454 |
| | FAK-Mediated mechanotransduction in skeletal regeneration | Q33282861 |
| | Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts | Q34087661 |
| | Low-magnitude mechanical loading becomes osteogenic when rest is inserted between each load cycle | Q34537551 |
| | G protein-coupled receptors sense fluid shear stress in endothelial cells | Q35108277 |
| | Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men | Q35738927 |
| | A model for the role of integrins in flow induced mechanotransduction in osteocytes | Q36023747 |
| | Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice | Q36119294 |
| | ATP- and gap junction-dependent intercellular calcium signaling in osteoblastic cells | Q36273913 |
| | Biomechanical and molecular regulation of bone remodeling | Q36533379 |
| | The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading | Q37165129 |
| | In situ microdialysis in bone tissue. Stimulation of prostaglandin E2 release by weight-bearing mechanical loading | Q37361702 |
| | Mechanotransduction and strain amplification in osteocyte cell processes | Q37693128 |
| | Wnt/beta-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha | Q40134766 |
| | LRP5 mutations linked to high bone mass diseases cause reduced LRP5 binding and inhibition by SOST. | Q40217824 |
| | Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling | Q40252553 |
| | Release of nitric oxide, but not prostaglandin E2, by bone cells depends on fluid flow frequency. | Q40279073 |
| | Response to mechanical strain in an immortalized pre-osteoblast cell is dependent on ERK1/2. | Q40328319 |
| | Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs | Q40426618 |
| | Mechanosensitivity of the rat skeleton decreases after a long period of loading, but is improved with time off. | Q40436880 |
| | Fluid shear stress induces beta-catenin signaling in osteoblasts. | Q40481605 |
| | Nitric oxide regulates receptor activator of nuclear factor-kappaB ligand and osteoprotegerin expression in bone marrow stromal cells. | Q40625414 |
| | Mechanotransduction and the functional response of bone to mechanical strain | Q40947864 |
| | Indomethacin modulation of load-related stimulation of new bone formation in vivo | Q41262052 |
| | Bone remodeling in response to in vivo fatigue microdamage | Q41498551 |
| | The role of nitric oxide in the mechanical repression of RANKL in bone stromal cells | Q42434396 |
| | Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis | Q42514385 |
| | Involvement of different ion channels in osteoblasts' and osteocytes' early responses to mechanical strain | Q42528170 |
| | Upregulation of osteopontin by osteocytes deprived of mechanical loading or oxygen | Q43164216 |
| | Role of inducible nitric oxide synthase in skeletal adaptation to acute increases in mechanical loading | Q44020449 |
| | L-type calcium channels mediate mechanically induced bone formation in vivo | Q44171624 |
| | Mechanical loading: biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone. | Q44245985 |
| | Humeral hypertrophy in response to exercise | Q44844633 |
| | Effects of immobilization on fetal bone development. A morphometric study in newborns with congenital neuromuscular diseases with intrauterine onset | Q45185937 |
| | Pressure-loaded MSCs during early osteodifferentiation promote osteoclastogenesis by increase of RANKL/OPG ratio | Q46160237 |
| | TGFbeta3 and loading increases osteocyte survival in human cancellous bone cultured ex vivo. | Q46183780 |
| | Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts | Q46272809 |
| | Leptin modulates both resorption and formation while preventing disuse-induced bone loss in tail-suspended female rats. | Q46449983 |
| | Activation of G proteins mediates flow-induced prostaglandin E2 production in osteoblasts | Q46825604 |
| | Noninvasive in vivo monitoring of bone architecture alterations in hindlimb-unloaded female rats using novel three-dimensional microcomputed tomography. | Q47632469 |
| | Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo. | Q50514494 |
| | Osteocytes subjected to fluid flow inhibit osteoclast formation and bone resorption. | Q50912442 |
| | Fluid flow induces Rankl expression in primary murine calvarial osteoblasts. | Q51254239 |
| | Effects of loading frequency on mechanically induced bone formation. | Q52064370 |
| | Three rules for bone adaptation to mechanical stimuli. | Q52231198 |
| | Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss. | Q53628612 |
| | Effect of bone strain on cortical bone structure in macaques (Macaca mulatta) | Q53773224 |
| | Bone adaptation to a mechanical loading program significantly increases skeletal fatigue resistance. | Q53861195 |
| | Skeletal unloading alleviates the anabolic action of intermittent PTH(1-34) in mouse tibia in association with inhibition of PTH-induced increase in c-fos mRNA in bone marrow cells. | Q54697938 |
| | Changes in shape, ossification and quality of bones in children with spina bifida | Q67532933 |
| | Loading-related increases in prostaglandin production in cores of adult canine cancellous bone in vitro: A role for prostacyclin in adaptive bone remodeling? | Q67710533 |
| | Mechanically adaptive bone remodelling | Q70403145 |
| | Reaction of bone to mechanical stimuli. 3. Microstructure of compact bone of rabbit tibia after intermittent loading | Q70428526 |
| | Regulation of bone formation by applied dynamic loads | Q71275906 |
| | The effect of dietary consistency on gross and histologic morphology in the craniofacial region of young rats | Q71379581 |
| | Osteocytic expression of mRNA for c-fos and IGF-I: an immediate early gene response to an osteogenic stimulus | Q71418094 |
| | Intracellular Ca2+ stores and extracellular Ca2+ are required in the real-time Ca2+ response of bone cells experiencing fluid flow | Q71732466 |
| | Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo | Q71773574 |
| | Inhibition of bone resorption and stimulation of formation by mechanical loading of the modeling rat ulna in vivo | Q71969107 |
| | Noninvasive loading of the rat ulna in vivo induces a strain-related modeling response uncomplicated by trauma or periostal pressure | Q72117775 |
| | Indomethacin has distinct early and late actions on bone formation induced by mechanical stimulation | Q72158600 |
| | Mechanical loading thresholds for lamellar and woven bone formation | Q72354956 |
| | The response of rat tibiae to incremental bouts of mechanical loading: a quantum concept for bone formation | Q72584872 |
| | Increased intracortical remodeling following fatigue damage | Q72838175 |
| | Five jumps per day increase bone mass and breaking force in rats | Q73673416 |
| | Osteoprotegerin mitigates tail suspension-induced osteopenia | Q73694172 |
| | Mechanical strain inhibits expression of osteoclast differentiation factor by murine stromal cells | Q73849776 |
| | Selected Contribution: Osteocytes upregulate HIF-1alpha in response to acute disuse and oxygen deprivation | Q73889063 |
| | Effects of nitric oxide synthase inhibitors on bone formation in rats | Q74045643 |
| | Modulation of appositional and longitudinal bone growth in the rat ulna by applied static and dynamic force | Q74363726 |
| | Activation of extracellular signal-regulated kinase is involved in mechanical strain inhibition of RANKL expression in bone stromal cells | Q74576148 |
| | Recovery periods restore mechanosensitivity to dynamically loaded bone | Q74631497 |
| | Mechanotransduction in the cortical bone is most efficient at loading frequencies of 5-10 Hz | Q76319093 |
| | Nitric oxide production by bone cells is fluid shear stress rate dependent | Q76383251 |
| | Localisation of prostaglandin endoperoxide H synthase (PGHS)-1 and PGHS-2 in bone following mechanical loading in vivo | Q77654292 |
| | Mechanical strain stimulates nitric oxide production by rapid activation of endothelial nitric oxide synthase in osteocytes | Q77995310 |
| | Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone | Q80111153 |
| | Inhibition of osteocyte apoptosis by fluid flow is mediated by nitric oxide | Q80867918 |
| | TOPGAL mice show that the canonical Wnt signaling pathway is active during bone development and growth and is activated by mechanical loading in vitro | Q81820767 |
| | Effects of hind limb unloading and reloading on nitric oxide synthase expression and apoptosis of osteocytes and chondrocytes | Q83963479 |
| P433 | issue | 4 | |
| P304 | page(s) | 319-338 | |
| P577 | publication date | 2009-01-01 | |
| P1433 | published in | Critical Reviews in Eukaryotic Gene Expression | Q5186666 |
| P1476 | title | Mechanical signaling for bone modeling and remodeling | |
| P478 | volume | 19 | |