| scholarly article | Q13442814 |
| P50 | author | Bodo Melnik | Q88156770 |
| P2093 | author name string | Christos C Zouboulis | |
| P2860 | cites work | AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1 | Q22254000 |
| TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver | Q24304147 | ||
| Signaling by target of rapamycin proteins in cell growth control | Q24522447 | ||
| Spatial regulation of the mTORC1 system in amino acids sensing pathway | Q24612853 | ||
| Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans | Q24618226 | ||
| Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony | Q24629514 | ||
| FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor | Q24632191 | ||
| mTOR: from growth signal integration to cancer, diabetes and ageing | Q24633662 | ||
| The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling | Q24794823 | ||
| Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation | Q28117650 | ||
| The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2 | Q28216784 | ||
| Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway | Q28271322 | ||
| Metabolic control by S6 kinases depends on dietary lipids | Q28731457 | ||
| Mediterranean diet and familial dysmetabolism as factors influencing the development of acne | Q44879558 | ||
| Zileuton, an oral 5-lipoxygenase inhibitor, directly reduces sebum production | Q45190459 | ||
| Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and acne lesion counts in adult women | Q46395742 | ||
| A pilot study to determine the short-term effects of a low glycemic load diet on hormonal markers of acne: a nonrandomized, parallel, controlled feeding trial | Q46581684 | ||
| Involvement of PPARgamma in oxidative stress-mediated prostaglandin E(2) production in SZ95 human sebaceous gland cells | Q46897023 | ||
| Insulin resistance and acne: a new risk factor for men? | Q47984084 | ||
| Testosterone metabolism to 5alpha-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytes. | Q50705226 | ||
| Regulation of SREBP1c gene expression in skeletal muscle: role of retinoid X receptor/liver X receptor and forkhead-O1 transcription factor. | Q51455793 | ||
| Effect of insulin-like growth factor-1 deficiency or administration on the occurrence of acne. | Q51534027 | ||
| Correlation of facial sebum to serum insulin-like growth factor-1 in patients with acne. | Q51872307 | ||
| Foxo1 in hepatic lipid metabolism. | Q53353228 | ||
| Clinical and histological effect of a low glycaemic load diet in treatment of acne vulgaris in Korean patients: a randomized, controlled trial. | Q53372858 | ||
| The role of FOXO in the regulation of metabolism. | Q54742441 | ||
| Milk consumption and acne in adolescent girls. | Q55042668 | ||
| A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial. | Q55044166 | ||
| Milk consumption: aggravating factor of acne and promoter of chronic diseases of Western societies | Q56601583 | ||
| An increased incidence of Propionibacterium acnes biofilms in acne vulgaris: a case-control study | Q60458150 | ||
| Forkhead Box O Transcription Factors: Key Players in Redox Signaling | Q63865775 | ||
| A longitudinal study of the relationship of plasma somatomedin-C concentration to the pubertal growth spurt | Q69009079 | ||
| Insulin inhibits the activation of transcription by a C-terminal fragment of the forkhead transcription factor FKHR. A mechanism for insulin inhibition of insulin-like growth factor-binding protein-1 transcription | Q73509889 | ||
| Growth hormone and insulin-like growth factors have different effects on sebaceous cell growth and differentiation | Q78180919 | ||
| The effect of a low glycemic load diet on acne vulgaris and the fatty acid composition of skin surface triglycerides | Q80452434 | ||
| Higher body mass index is a significant risk factor for acne formation in schoolchildren | Q83366907 | ||
| Whey protein precipitating moderate to severe acne flares in 5 teenaged athletes | Q84988857 | ||
| FoxO1 mediates PTEN suppression of androgen receptor N- and C-terminal interactions and coactivator recruitment | Q39906248 | ||
| LXRalpha enhances lipid synthesis in SZ95 sebocytes | Q40062571 | ||
| The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor | Q40091020 | ||
| Peroxisome proliferator-activated receptors increase human sebum production | Q40283470 | ||
| FoxO-dependent and -independent mechanisms mediate SirT1 effects on IGFBP-1 gene expression | Q40360245 | ||
| Convergence of peroxisome proliferator-activated receptor gamma and Foxo1 signaling pathways | Q40635898 | ||
| The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors | Q42067514 | ||
| Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes | Q42446253 | ||
| Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis | Q42601114 | ||
| The influence of dietary patterns on acne vulgaris in Koreans | Q42914845 | ||
| Short-term isotretinoin treatment decreases insulin-like growth factor-1 and insulin-like growth factor binding protein-3 levels: does isotretinoin affect growth hormone physiology? | Q43175478 | ||
| Acne and whey protein supplementation among bodybuilders | Q43494823 | ||
| Prevalence, severity, and severity risk factors of acne in high school pupils: a community-based study | Q43864303 | ||
| FOXO-dependent regulation of innate immune homeostasis | Q43911990 | ||
| Relationship between the growth hormone/insulin-like growth factor-I axis, insulin sensitivity, and adrenal androgens in normal prepubertal and pubertal girls | Q44357275 | ||
| IRES-mediated functional coupling of transcription and translation amplifies insulin receptor feedback | Q28763839 | ||
| FoxO3 controls autophagy in skeletal muscle in vivo | Q29614483 | ||
| Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress | Q29614493 | ||
| Ras, PI(3)K and mTOR signalling controls tumour cell growth | Q29614734 | ||
| Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1). | Q33606105 | ||
| Nutrient sensing and inflammation in metabolic diseases | Q33623354 | ||
| Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. | Q33797113 | ||
| FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1. | Q33855172 | ||
| With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging | Q33912952 | ||
| Acne vulgaris: a disease of Western civilization | Q33963012 | ||
| IGF-1 induces SREBP-1 expression and lipogenesis in SEB-1 sebocytes via activation of the phosphoinositide 3-kinase/Akt pathway. | Q33988649 | ||
| Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex | Q34007618 | ||
| Role of hormones in pilosebaceous unit development | Q34009592 | ||
| Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation | Q34089899 | ||
| The forkhead transcription factor Foxo1 regulates adipocyte differentiation | Q34170890 | ||
| High glycemic load diet, milk and ice cream consumption are related to acne vulgaris in Malaysian young adults: a case control study | Q34381936 | ||
| Highly specialized role of Forkhead box O transcription factors in the immune system. | Q34492548 | ||
| Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models | Q34514818 | ||
| FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity. | Q34521158 | ||
| Inflammatory events are involved in acne lesion initiation | Q34535060 | ||
| High school dietary dairy intake and teenage acne | Q34554810 | ||
| The prevalence of acne in adults 20 years and older | Q34583936 | ||
| Milk consumption and acne in teenaged boys | Q34587075 | ||
| Role of insulin, insulin-like growth factor-1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris | Q34611221 | ||
| The two TORCs and Akt. | Q34617423 | ||
| The effect of a high-protein, low glycemic-load diet versus a conventional, high glycemic-load diet on biochemical parameters associated with acne vulgaris: a randomized, investigator-masked, controlled trial | Q34621172 | ||
| Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults | Q34636368 | ||
| An update on the role of the sebaceous gland in the pathogenesis of acne | Q34637981 | ||
| Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb | Q34700113 | ||
| Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism | Q34945194 | ||
| Oxidative stress in patients with acne vulgaris | Q34945543 | ||
| Milk consumption: aggravating factor of acne and promoter of chronic diseases of Western societies | Q34951913 | ||
| Over-stimulation of insulin/IGF-1 signaling by western diet may promote diseases of civilization: lessons learnt from laron syndrome | Q35121240 | ||
| Hyperinsulinemic diseases of civilization: more than just Syndrome X | Q35550817 | ||
| Isotretinoin and FoxO1: A scientific hypothesis | Q35558873 | ||
| The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation | Q35684376 | ||
| Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation. | Q35694048 | ||
| Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance | Q36020413 | ||
| Dietary intervention in acne: Attenuation of increased mTORC1 signaling promoted by Western diet | Q36130010 | ||
| Interplay between FOXO, TOR, and Akt. | Q36189618 | ||
| Androgen activation of the sterol regulatory element-binding protein pathway: Current insights. | Q36385548 | ||
| The impact of cow's milk-mediated mTORC1-signaling in the initiation and progression of prostate cancer | Q36402333 | ||
| FoxO is a critical regulator of stem cell maintenance in immortal Hydra | Q36438537 | ||
| Genome-wide analysis of FoxO1 binding in hepatic chromatin: potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis | Q36478114 | ||
| Dynamic FoxO transcription factors | Q36889897 | ||
| The FoxO transcription factors and metabolic regulation | Q37005651 | ||
| Clever cancer strategies with FoxO transcription factors | Q37071395 | ||
| Amino acid regulation of TOR complex 1. | Q37162253 | ||
| An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance | Q37217188 | ||
| PTEN and the PI3-kinase pathway in cancer | Q37259680 | ||
| A new player in the orchestra of cell growth: SREBP activity is regulated by mTORC1 and contributes to the regulation of cell and organ size | Q37368338 | ||
| LKB1 and AMP-activated protein kinase control of mTOR signalling and growth | Q37383513 | ||
| Mechanism of androgen receptor action | Q37446332 | ||
| Nutrient control of TORC1, a cell-cycle regulator | Q37472419 | ||
| Forkhead transcription factors in chronic inflammation | Q37619795 | ||
| FoxO1 - the key for the pathogenesis and therapy of acne? | Q37691463 | ||
| Foxo1 integrates insulin signaling with mitochondrial function in the liver | Q37715192 | ||
| The Extending Network of FOXO Transcriptional Target Genes | Q37776729 | ||
| The role of transcription factor FoxO1 in the pathogenesis of acne vulgaris and the mode of isotretinoin action | Q37798709 | ||
| mTORC1 signaling: what we still don't know | Q37817590 | ||
| Acne-associated syndromes: models for better understanding of acne pathogenesis | Q37825558 | ||
| Nutrition and acne: therapeutic potential of ketogenic diets. | Q37983368 | ||
| Acne vulgaris: the role of oxidative stress and the potential therapeutic value of local and systemic antioxidants. | Q38014706 | ||
| Updated knowledge about polyphenols: functions, bioavailability, metabolism, and health | Q38022685 | ||
| Mitochondrial oxidative stress and the metabolic syndrome | Q38029441 | ||
| Low serum insulin in traditional Pacific Islanders--the Kitava Study | Q39181702 | ||
| TNF-α increases lipogenesis via JNK and PI3K/Akt pathways in SZ95 human sebocytes | Q39401778 | ||
| FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes | Q39879302 | ||
| Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway | Q39896136 | ||
| P433 | issue | 5 | |
| P921 | main subject | pathogenesis | Q372016 |
| P304 | page(s) | 311-315 | |
| P577 | publication date | 2013-05-01 | |
| P1433 | published in | Experimental Dermatology | Q15749509 |
| P1476 | title | Potential role of FoxO1 and mTORC1 in the pathogenesis of Western diet-induced acne | |
| P478 | volume | 22 |
| Q34458584 | A global perspective on the epidemiology of acne |
| Q38147420 | A practical guide for the study of human and murine sebaceous glands in situ |
| Q38153454 | Acne is an inflammatory disease and alterations of sebum composition initiate acne lesions |
| Q89219160 | Acne vulgaris |
| Q61808168 | Adult female acne: a guide to clinical practice |
| Q37101662 | Are therapeutic effects of antiacne agents mediated by activation of FoxO1 and inhibition of mTORC1? |
| Q39145897 | Azelaic acid 20 % cream: effects on quality of life and disease severity in adult female acne patients |
| Q38977482 | Beyond acne: Current aspects of sebaceous gland biology and function |
| Q90700706 | Butterfly Effect - the Concept and the Implications in Dermatology, Acne, and Rosacea |
| Q100750148 | Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis |
| Q34054320 | Correlation between the severity and type of acne lesions with serum zinc levels in patients with acne vulgaris |
| Q26851291 | Cutting through the complexities of mTOR for the treatment of stroke |
| Q47775057 | Different strains of Propionibacterium acnes modulate differently the cutaneous innate immunity |
| Q91666107 | Diseases of Civilization - Cancer, Diabetes, Obesity and Acne - the Implication of Milk, IGF-1 and mTORC1 |
| Q56959574 | Do tetracyclines and erythromycin exert anti-acne effects by inhibition of P450-mediated degradation of retinoic acid? |
| Q37741206 | Green Tea and Other Tea Polyphenols: Effects on Sebum Production and Acne Vulgaris |
| Q53569569 | Inhibition of retinoic acid catabolism by minocycline: evidence for a novel mode of action? |
| Q53843026 | Insulin resistance and skin diseases. |
| Q34674814 | Is sebocyte-derived leptin the missing link between hyperseborrhea, ductal hypoxia, inflammation and comedogenesis in acne vulgaris? |
| Q38884514 | L-Ascorbyl-2-phosphate attenuates NF-κB signaling in SZ95 sebocytes without affecting IL-6 and IL-8 secretion |
| Q26800264 | Linking diet to acne metabolomics, inflammation, and comedogenesis: an update |
| Q26747836 | Management of Hidradenitis Suppurativa in Patients with Metabolic Comorbidities |
| Q52779156 | Mechanistic target of rapamycin complex 1 is involved in psoriasis and regulated by anti-TNF-α treatment. |
| Q24594618 | Milk is not just food but most likely a genetic transfection system activating mTORC1 signaling for postnatal growth |
| Q26801523 | Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent Translation |
| Q36086022 | Preliminary evidence for vitamin D deficiency in nodulocystic acne |
| Q38827186 | Sebocytes differentially express and secrete adipokines |
| Q54220200 | Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin-like growth factor-1 in patients with acne vulgaris and their relationship with diet. |
| Q34603651 | Taking aim at Alzheimer's disease through the mammalian target of rapamycin |
| Q38191671 | The aetiopathogenesis of acne vulgaris - what's new? |
| Q26767243 | The epidemiology of acne vulgaris in late adolescence |
| Q37531845 | The possible role of diet in the pathogenesis of adult female acne |
| Q33356076 | Turning acne on/off via mTORC1 |
| Q38341846 | What's new in the physiopathology of acne? |
| Q41715894 | p53: key conductor of all anti-acne therapies |
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