| scholarly article | Q13442814 |
| P50 | author | Bogdan A Stoica | Q56088398 |
| David J Loane | Q63812916 | ||
| Margaret I. Davis | Q40630470 | ||
| Kimberly R. Byrnes | Q40828257 | ||
| P2093 | author name string | Alan I Faden | |
| Angela Riccio | |||
| P2860 | cites work | Cyclosporine-A treatment inhibits the expression of metabotropic glutamate receptors in rat thymus | Q60684992 |
| Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis | Q71607261 | ||
| Time dependency of the action of nitric oxide in lipopolysaccharide-interferon-gamma-induced neuronal cell death in murine primary neuron-glia co-cultures | Q73081372 | ||
| Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro | Q73756741 | ||
| Tumor necrosis factor receptor deletion reduces nuclear factor-kappaB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury | Q74411614 | ||
| Peripheral metabotropic glutamate receptor 5 mediates mechanical hypersensitivity in craniofacial muscle via protein kinase C dependent mechanisms | Q79789656 | ||
| Cyclothiazide selectively inhibits mGluR1 receptors interacting with a common allosteric site for non-competitive antagonists | Q24681622 | ||
| Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration | Q24815912 | ||
| Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury | Q28138050 | ||
| TNF alpha potentiates glutamate neurotoxicity by inhibiting glutamate uptake in organotypic brain slice cultures: neuroprotection by NF kappa B inhibition | Q28235171 | ||
| Neuroprotective effects of group III mGluR in traumatic neuronal injury | Q28262691 | ||
| Characterization of modulatory effects of postsynaptic metabotropic glutamate receptors on calcium currents in rat nucleus tractus solitarius | Q28284932 | ||
| Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII | Q28576309 | ||
| The metabotropic glutamate receptors: structure and functions | Q28611140 | ||
| Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism | Q29615446 | ||
| Selective blockade of the mGluR1 receptor reduces traumatic neuronal injury in vitro and improvesoOutcome after brain trauma | Q31848501 | ||
| TNF-alpha stimulates caspase-3 activation and apoptotic cell death in primary septo-hippocampal cultures. | Q33181856 | ||
| Review of oxidative stress in brain and spinal cord injury: suggestions for pharmacological and nutritional management strategies | Q33545928 | ||
| Free radical pathways in CNS injury | Q34076422 | ||
| Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation | Q34325464 | ||
| Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors | Q34410375 | ||
| Caspase-dependent apoptotic pathways in CNS injury | Q34520118 | ||
| Neuroprotective activity of selective mGlu1 and mGlu5 antagonists in vitro and in vivo. | Q34582262 | ||
| Metabotropic glutamate receptor antagonists and agonists: potential neuroprotectors in diffuse brain injury | Q34582778 | ||
| Microglia: neuroprotective and neurotrophic cells in the central nervous system | Q35699032 | ||
| Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention | Q36919403 | ||
| Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function. | Q39750102 | ||
| Selective activation of group III metabotropic glutamate receptors by L-(+)-2-amino-4-phosphonobutryic acid protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo. | Q40283237 | ||
| Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide | Q40300046 | ||
| An emerging family of dual specificity MAP kinase phosphatases | Q40493476 | ||
| Microglial activation induces cell death, inhibits neurite outgrowth and causes neurite retraction of differentiated neuroblastoma cells | Q40654925 | ||
| Glutamate release from activated microglia requires the oxidative burst and lipid peroxidation. | Q41874775 | ||
| Systemically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats | Q42612978 | ||
| Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: role of p47phox phosphorylation and binding to TRAF4. | Q42702109 | ||
| Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia | Q43823127 | ||
| Involvement of inducible nitric oxide synthase in inflammation-induced dopaminergic neurodegeneration | Q43908040 | ||
| Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up-regulated in Alzheimer's disease. | Q44163232 | ||
| Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity. | Q44376556 | ||
| Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis | Q44477073 | ||
| Role of nitric oxide in rotenone-induced nigro-striatal injury | Q44570041 | ||
| MGLuR5 activation reduces beta-amyloid-induced cell death in primary neuronal cultures and attenuates translocation of cytochrome c and apoptosis-inducing factor | Q44930741 | ||
| The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism | Q45153616 | ||
| Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate | Q45310416 | ||
| Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand. | Q46384476 | ||
| Signal transduction pathways regulating cyclooxygenase-2 in lipopolysaccharide-activated primary rat microglia | Q46413171 | ||
| Expression of two temporally distinct microglia-related gene clusters after spinal cord injury | Q46848381 | ||
| Neuroprotective effects of selective group II mGluR activation in brain trauma and traumatic neuronal injury | Q46965046 | ||
| LY379268, a potent and selective Group II metabotropic glutamate receptor agonist, is neuroprotective in gerbil global, but not focal, cerebral ischaemia | Q48095150 | ||
| Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment | Q48220313 | ||
| Expression and signaling of group I metabotropic glutamate receptors in astrocytes and microglia | Q48251087 | ||
| Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury | Q48392846 | ||
| Mechanical injury to neuronal/glial cultures in microplates: role of NMDA receptors and pH in secondary neuronal cell death | Q48490138 | ||
| Inhibition of the expression of mitogen-activated protein phosphatase-1 potentiates apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. | Q54136924 | ||
| P433 | issue | 5 | |
| P921 | main subject | microglial inhibitor | Q63100844 |
| microglia | Q1622829 | ||
| neurotoxicity | Q3338704 | ||
| toxic encephalopathy | Q7830379 | ||
| inflammation | Q101991 | ||
| P304 | page(s) | 550-560 | |
| P577 | publication date | 2009-04-01 | |
| P1433 | published in | Glia | Q15716658 |
| P1476 | title | Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity | |
| P478 | volume | 57 |
| Q33624417 | A Novel Bio-Psychosocial-Behavioral Treatment Model in Schizophrenia. |
| Q48245285 | Activation of mGluR5 Attenuates Microglial Activation and Neuronal Apoptosis in Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats |
| Q36661183 | Activation of mGluR5 and inhibition of NADPH oxidase improves functional recovery after traumatic brain injury |
| Q37128209 | Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents |
| Q37471244 | Aβ and Inflammatory Stimulus Activate Diverse Signaling Pathways in Monocytic Cells: Implications in Retaining Phagocytosis in Aβ-Laden Environment |
| Q37704621 | Bone fracture exacerbates murine ischemic cerebral injury |
| Q38182045 | Calcium ion influx in microglial cells: physiological and therapeutic significance |
| Q37426292 | Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury |
| Q35064981 | Chronic neurodegeneration after traumatic brain injury: Alzheimer disease, chronic traumatic encephalopathy, or persistent neuroinflammation? |
| Q35842329 | Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury |
| Q42722828 | Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia. |
| Q60920725 | Emerging Trends in Pain Modulation by Metabotropic Glutamate Receptors |
| Q48374986 | Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic glutamate 5 receptors: adolescent administration prevents adult-onset deficits induced by neonatal treatment with phencyclidine |
| Q45991086 | Evidence group I mGluR drugs modulate the activation profile of lipopolysaccharide-exposed microglia in culture. |
| Q94562610 | Exosomes derived from neural progenitor cells preserve photoreceptors during retinal degeneration by inactivating microglia |
| Q64898684 | Fluorescent Light Incites a Conserved Immune and Inflammatory Genetic Response within Vertebrate Organs (Danio Rerio, Oryzias Latipes and Mus Musculus). |
| Q37528939 | Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice |
| Q33936937 | Group I metabotropic glutamate receptor mediated dynamic immune dysfunction in children with fragile X syndrome |
| Q38939473 | Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive Gi-proteins in murine BV-2 microglia cells |
| Q35831877 | Loss of Metabotropic Glutamate Receptor 5 Function on Peripheral Benzodiazepine Receptor in Mice Prenatally Exposed to LPS. |
| Q41768557 | Metabotropic Glutamate Receptors Protect Oligodendrocytes from Acute Ischemia in the Mouse Optic Nerve |
| Q59335641 | Metabotropic Glutamate Receptors in Glial Cells: A New Potential Target for Neuroprotection? |
| Q41564939 | Metabotropic glutamate receptor 5 deficiency inhibits neutrophil infiltration after traumatic brain injury in mice |
| Q41840818 | Metabotropic glutamate receptor 5 may be involved in macrophage plasticity |
| Q57021675 | Metabotropic glutamate receptor subtype 5 is altered in LPS-induced murine neuroinflammation model and in the brains of AD and ALS patients |
| Q28385047 | Metabotropic glutamate receptor-mediated signaling in neuroglia |
| Q37358665 | Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders |
| Q36144340 | Metabotropic glutamate receptors inhibit microglial glutamate release. |
| Q90564251 | Microglia Receptors in Animal Models of Traumatic Brain Injury |
| Q36399682 | Microglia in the TBI brain: The good, the bad, and the dysregulated. |
| Q38207363 | Microglia toxicity in preterm brain injury |
| Q37794381 | Microglial activation in stroke: therapeutic targets |
| Q47899668 | Microglial modulation of neuronal activity in the healthy brain |
| Q38166592 | Neurogenic neuroinflammation: inflammatory CNS reactions in response to neuronal activity |
| Q37698259 | Neuroinflammation is associated with changes in glial mGluR5 expression and the development of neonatal excitotoxic lesions |
| Q37365637 | Neuroprotective effects of geranylgeranylacetone in experimental traumatic brain injury |
| Q38726690 | Neuroteratology and Animal Modeling of Brain Disorders |
| Q41678707 | Neurotransmitter receptors on microglia |
| Q38926246 | New drug developments in psychosis: Challenges, opportunities and strategies |
| Q39445567 | Novel mGluR5 positive allosteric modulator improves functional recovery, attenuates neurodegeneration, and alters microglial polarization after experimental traumatic brain injury |
| Q35006471 | Novel neuroinflammatory targets in the chronically injured spinal cord |
| Q57475900 | Positive modulation of mGluR5 attenuates seizures and reduces TNF-α macrophages and microglia in the brain in a murine model of virus-induced temporal lobe epilepsy |
| Q28078621 | Precision Medicine in Multiple Sclerosis: Future of PET Imaging of Inflammation and Reactive Astrocytes |
| Q37663731 | Predicting the diagnosis of autism spectrum disorder using gene pathway analysis |
| Q41563682 | Primary microglia isolation from mixed glial cell cultures of neonatal rat brain tissue |
| Q92193150 | Quantum Dot Cellular Uptake and Toxicity in the Developing Brain: Implications for Use as Imaging Probes |
| Q47154070 | Shedding of Microvesicles from Microglia Contributes to the Effects Induced by Metabotropic Glutamate Receptor 5 Activation on Neuronal Death. |
| Q33666643 | Simulated whiplash modulates expression of the glutamatergic system in the spinal cord suggesting spinal plasticity is associated with painful dynamic cervical facet loading |
| Q38185074 | Supraspinal metabotropic glutamate receptors: a target for pain relief and beyond |
| Q34073426 | System x(c)(-) regulates microglia and macrophage glutamate excitotoxicity in vivo |
| Q64261706 | Targeting mGlu Receptors for Optimization of Antipsychotic Activity and Disease-Modifying Effect in Schizophrenia |
| Q36844773 | The Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator ADX88178 Inhibits Inflammatory Responses in Primary Microglia |
| Q38751303 | The Polarization States of Microglia in TBI: A New Paradigm for Pharmacological Intervention. |
| Q58701739 | The effects of insulin on the inflammatory activity of BV2 microglia |
| Q30235977 | The far-reaching scope of neuroinflammation after traumatic brain injury |
| Q38924641 | The mGluR5 positive allosteric modulator CDPPB inhibits SO₂-induced protein radical formation and mitochondrial dysfunction through activation of Akt in mouse hippocampal HT22 cells |
| Q21262024 | The orthosteric agonist 2-chloro-5-hydroxyphenylglycine activates mGluR5 and mGluR1 with similar efficacy and potency |
| Q35698522 | Therapeutic potential of mGluR5 targeting in Alzheimer's disease |
| Q35984897 | Voluntary Exercise Preconditioning Activates Multiple Antiapoptotic Mechanisms and Improves Neurological Recovery after Experimental Traumatic Brain Injury |
| Q36010787 | Whiplash-like facet joint loading initiates glutamatergic responses in the DRG and spinal cord associated with behavioral hypersensitivity |
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