| P2093 | author name string | T Chiba | |
| | I Shimokawa | |
| | H Yamaza | |
| P2860 | cites work | Association of LKB1 with a WD-repeat protein WDR6 is implicated in cell growth arrest and p27(Kip1) induction | Q24292853 |
| | A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility | Q24532227 |
| | A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse) | Q24654776 |
| | Molecular cloning, expression analysis, and chromosome mapping of WDR6, a novel human WD-repeat gene | Q28141372 |
| | The WD repeat: a common architecture for diverse functions | Q28143827 |
| | Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein | Q28211215 |
| | The ancient regulatory-protein family of WD-repeat proteins | Q28248516 |
| | Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice | Q28252794 |
| | AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus | Q28254114 |
| | Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit | Q28259869 |
| | Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production | Q28511652 |
| | GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function | Q28512102 |
| | Food restriction in rodents: an evaluation of its role in the study of aging | Q39637731 |
| | Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice | Q42521448 |
| | Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway. | Q42610778 |
| | Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway | Q43909621 |
| | Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-1 and IRS-2 in liver of Ames dwarf mice | Q43943139 |
| | Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span | Q44559269 |
| | A transgenic dwarf rat model as a tool for the study of calorie restriction and aging | Q44809091 |
| | Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1. | Q44814519 |
| | Roles of the lactogens and somatogens in perinatal and postnatal metabolism and growth: studies of a novel mouse model combining lactogen resistance and growth hormone deficiency | Q45075512 |
| | Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila | Q46506998 |
| | Autophagy is required for dietary restriction-mediated life span extension in C. elegans | Q47068665 |
| | Discrete expression of insulin receptor substrate-4 mRNA in adult rat brain | Q48090584 |
| | Involvement of insulin-like growth factor-1 in the effect of caloric restriction: regulation of plasma adiponectin and leptin | Q48272709 |
| | Premature ageing in transgenic mice expressing different growth hormone genes | Q48386543 |
| | Identification of fasting-induced genes in the rat hypothalamus: relationship with neuroprotection. | Q51458650 |
| | Identification of differentially expressed genes in senescence-accelerated mouse testes by suppression subtractive hybridization analysis. | Q51992881 |
| | Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis. | Q52537778 |
| | Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. | Q52539802 |
| | Dwarf mice and the ageing process. | Q55066759 |
| | Food, reproduction and L'ongevity: Is the extended lifespan of calorie-restricted animals an evolutionary adaptation? | Q56854472 |
| | Lifespan extension by reduction of the growth hormone‐insulin‐like growth factor‐1 axis: relation to caloric restriction | Q73262309 |
| | Fibroblast growth factor inhibits locomotor activity as well as feeding behavior of rats | Q73701433 |
| | The Snell dwarf mutation Pit1(dw) can increase life span in mice | Q77218978 |
| | Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: implications for longevity | Q28578385 |
| | Autophagy genes are essential for dauer development and life-span extension in C. elegans | Q29614180 |
| | Extended longevity in mice lacking the insulin receptor in adipose tissue | Q29614549 |
| | The p66shc adaptor protein controls oxidative stress response and life span in mammals | Q29614553 |
| | IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice | Q29616382 |
| | A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans | Q29617059 |
| | Autophagy in cell death: an innocent convict? | Q29617604 |
| | A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function | Q29618026 |
| | Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries | Q29618999 |
| | Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling | Q29619762 |
| | The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis | Q29622875 |
| | Revisiting the role of fat mass in the life extension induced by caloric restriction | Q33587305 |
| | A role for leptin in the antiaging action of dietary restriction: a hypothesis. | Q33876271 |
| | Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant | Q33890251 |
| | Caloric restriction and aging: an update | Q33930339 |
| | Extending the lifespan of long-lived mice | Q34102936 |
| | Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance | Q34137882 |
| | Tyrosine phosphoproteomics of fibroblast growth factor signaling: a role for insulin receptor substrate-4. | Q34341785 |
| | Genetics of lifespan in C. elegans: molecular diversity, physiological complexity, mechanistic simplicity | Q34446119 |
| | Genetic mouse models of extended lifespan | Q34544303 |
| | Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction | Q34595363 |
| | Brain IRS2 signaling coordinates life span and nutrient homeostasis | Q34653913 |
| | Anti-aging effects of caloric restriction: Involvement of neuroendocrine adaptation by peripheral signaling | Q34993175 |
| | Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model | Q35747940 |
| | A genome-scale map of expression for a mouse brain section obtained using voxelation | Q35821576 |
| | The role of macroautophagy in the ageing process, anti-ageing intervention and age-associated diseases | Q35869371 |
| | Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance | Q35945000 |
| | IGF-1 signaling and aging. | Q35974885 |
| | The role of insulin and IGF-1 signaling in longevity | Q36050369 |
| | AMP-activated protein kinase: balancing the scales. | Q36055807 |
| | Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging | Q36141285 |
| | Extended longevity and insulin signaling in adipose tissue | Q36242275 |
| | Control of aging and longevity by IGF-I signaling | Q36254254 |
| | Tissue-specific roles of IRS proteins in insulin signaling and glucose transport | Q36386892 |
| | Autophagy in neurodegenerative disease: friend, foe or turncoat? | Q36543319 |
| | The Mr 140,000 intermediate chain of Chlamydomonas flagellar inner arm dynein is a WD-repeat protein implicated in dynein arm anchoring | Q36927149 |
| | Receptors and neurosecretory actions of endothelin in hypothalamic neurons | Q37641504 |
| P433 | issue | 7 | |
| P921 | main subject | calorie restriction | Q1332886 |
| | preproinsulin | Q7240673 |
| | lifetime | Q22675021 |
| P304 | page(s) | 423-428 | |
| P577 | publication date | 2007-11-01 | |
| P1433 | published in | Current Genomics | Q5195047 |
| P1476 | title | Role of insulin and growth hormone/insulin-like growth factor-I signaling in lifespan extension: rodent longevity models for studying aging and calorie restriction | |
| P478 | volume | 8 | |