Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial

scientific article published on June 2008

Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0140-6736(08)60920-4
P932PMC publication ID2650104
P698PubMed publication ID18572080
P5875ResearchGate publication ID5284570

P50authorLawrence CoreyQ6503944
Susan BuchbinderQ7647625
Frances M. CowanQ41729082
Connie CelumQ42571941
Sinead Delany-MoretlweQ42572161
Stewart ReidQ43131832
Beryl A KoblinQ88472825
James P HughesQ90437729
Martín CasapíaQ91360469
Jonathan FuchsQ114517190
Anna WaldQ41122225
P2093author name stringJing Wang
Jorge Sanchez
Sheryl Zwerski
Abner Ortiz
HPTN 039 Protocol Team
Scott Rose
P2860cites workReactivation of genital herpes simplex virus type 2 infection in asymptomatic seropositive personsQ43704029
Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virusQ43932851
Impact of suppressive herpes therapy on genital HIV-1 RNA among women taking antiretroviral therapy: a randomized controlled trialQ43932977
Valacyclovir and acyclovir for suppression of shedding of herpes simplex virus in the genital tractQ45066119
Polymerase chain reaction for detection of herpes simplex virus (HSV) DNA on mucosal surfaces: comparison with HSV isolation in cell cultureQ45162165
Herpes simplex virus (HSV) suppression with valacyclovir reduces rectal and blood plasma HIV-1 levels in HIV-1/HSV-2-seropositive men: a randomized, double-blind, placebo-controlled crossover trialQ45399240
Association of herpes simplex virus type 2 infection and syphilis with human immunodeficiency virus infection among men who have sex with men in PeruQ45410894
High risk of human immunodeficiency virus in men who have sex with men with herpes simplex virus type 2 in the EXPLORE studyQ45413573
Herpes simplex virus type 2 (HSV-2) Western blot confirmatory testing among men testing positive for HSV-2 using the focus enzyme-linked immunosorbent assay in a sexually transmitted disease clinicQ45422116
Herpes simplex virus type-1 can reactivate transcription of latent human immunodeficiency virusQ45721318
Recent herpes simplex virus type 2 infection and the risk of human immunodeficiency virus type 1 acquisition in IndiaQ45723796
Valaciclovir for the suppression of recurrent genital herpes simplex virus infection: a large-scale dose range-finding study. International Valaciclovir HSV Study GroupQ45753939
Long-term acyclovir suppression of frequently recurring genital herpes simplex virus infection. A multicenter double-blind trialQ45832697
Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretationQ24645157
Comparison of Western blot (immunoblot) and glycoprotein G-specific immunodot enzyme assay for detecting antibodies to herpes simplex virus types 1 and 2 in human seraQ24649122
A Multiple Testing Procedure for Clinical TrialsQ28248823
Clinical efficacy of high-dose acyclovir in patients with human immunodeficiency virus infection: a meta-analysis of randomized individual patient dataQ32041499
Quantitative stability of DNA after extended storage of clinical specimens as determined by real-time PCR.Q33963010
Epidemiology of herpes simplex virus type 2 infection in the developing worldQ34317191
Risk of human immunodeficiency virus infection in herpes simplex virus type 2-seropositive persons: a meta-analysisQ34470594
Sexually transmitted diseases treatment guidelines, 2006.Q34554277
The effects of herpes simplex virus-2 on HIV-1 acquisition and transmission: a review of two overlapping epidemicsQ35691394
Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies.Q36331074
Effect of herpes simplex suppression on incidence of HIV among women in TanzaniaQ37098217
Herpes simplex virus (HSV)-suppressive therapy decreases plasma and genital HIV-1 levels in HSV-2/HIV-1 coinfected women: a randomized, placebo-controlled, cross-over trialQ37149672
Performance of a commercial, type-specific enzyme-linked immunosorbent assay for detection of herpes simplex virus type 2-specific antibodies in UgandansQ37419798
Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, UgandaQ38885289
Negative mucosal synergy between Herpes simplex type 2 and HIV in the female genital tractQ39787490
P433issue9630
P407language of work or nameEnglishQ1860
P921main subjectvirusQ808
aciclovirQ147101
HIVQ15787
men who have sex with menQ853451
placeboQ269829
placebo-controlled trialQ108853737
P304page(s)2109-2119
P577publication date2008-06-01
P1433published inThe LancetQ939416
P1476titleEffect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial
P478volume371