Using gene transfer to circumvent off-target effects

scientific article published on 20 March 2008

Using gene transfer to circumvent off-target effects is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1038/GT.2008.43
P698PubMed publication ID18356813
P5875ResearchGate publication ID5495277

P2093author name stringC A Blau
C P Miller
P2860cites workCellular signaling by fibroblast growth factor receptorsQ24301087
Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificityQ27765263
Erythropoietin blockade inhibits the induction of tumor angiogenesis and progressionQ33288270
JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cellsQ34087180
Side effects of retroviral gene transfer into hematopoietic stem cellsQ34168349
Pharmacologically regulated cell therapyQ34225667
Anemia as an independent prognostic factor for survival in patients with cancer: a systemic, quantitative reviewQ34286438
Controlling Signal Transduction with Synthetic LigandsQ34306937
A chromatin insulator protects retrovirus vectors from chromosomal position effectsQ35198059
Erythropoietin receptor mRNA expression in human endothelial cellsQ35208338
Growth factor receptors as regulators of hematopoiesisQ35848814
A proliferation switch for genetically modified cellsQ36077799
Targeted expansion of genetically modified bone marrow cellsQ36167363
The anaemia of cancer: death by a thousand cutsQ36167596
Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: a survival studyQ36222669
Inhibition of erythropoietin signalling destroys xenografts of ovarian and uterine cancers in nude miceQ36622808
Erythropoietin in cancer: presumption of innocence?Q36803489
Control of myoblast proliferation with a synthetic ligandQ38297845
Functional significance of erythropoietin receptor expression in breast cancerQ38364203
Selection with a regulated cell growth switch increases the likelihood of expression for a linked gamma-globin geneQ40424440
Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinomaQ40430272
Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cellsQ40492460
Small-molecule-directed mpl signaling can complement growth factors to selectively expand genetically modified cord blood cellsQ40677385
Dimerizer-induced proliferation of genetically modified hepatocytesQ40739020
Receptor specificity in the self-renewal and differentiation of primary multipotential hemopoietic cells.Q40795297
An inducible caspase 9 safety switch for T-cell therapyQ41768001
Extended core sequences from the cHS4 insulator are necessary for protecting retroviral vectors from silencing position effectsQ42829430
A bloodless revolution. A growing interest in artificial blood substitutes has resulted in new products that could soon improve transfusion medicineQ43205596
Pharmacologically regulated in vivo selection in a large animalQ44117631
Modulating erythrocyte chimerism in a mouse model of pyruvate kinase deficiencyQ44779183
In vivo selection of genetically modified erythroid cells using a jak2-based cell growth switchQ45036079
Pharmacologically regulated regeneration of functional human pancreatic islets.Q45178243
In vivo selection using a cell-growth switchQ45870526
T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patientsQ45876112
Anatomical compartments modify the response of human hematopoietic cells to a mitogenic signalQ46864865
Pharmacologically regulated Fas-mediated death of adoptively transferred T cells in a nonhuman primate model.Q47438492
Erythropoietin regulates tumour growth of human malignanciesQ48280802
Expression of erythropoietin receptor splice variants in human cancer.Q51835125
Randomized, double-blind, placebo-controlled trial of erythropoietin in non-small-cell lung cancer with disease-related anemia.Q53204531
Relation of Erythropoietin and Erythropoietin Receptor Expression to Hypoxia and Anemia in Head and Neck Squamous Cell CarcinomaQ58211963
Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivoQ59067674
Preclinical and Clinical Studies with Recombinant Human Basic Fibroblast Growth FactorQ67847584
Hypotensive activity of fibroblast growth factorQ68066299
Intravenous safety and pharmacokinetics of a novel dimerizer drug, AP1903, in healthy volunteersQ74370488
Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trialQ79202551
P433issue10
P304page(s)759-764
P577publication date2008-03-20
P1433published inGene TherapyQ15763095
P1476titleUsing gene transfer to circumvent off-target effects
P478volume15

Reverse relations

cites work (P2860)
Q34755217A composite MyD88/CD40 switch synergistically activates mouse and human dendritic cells for enhanced antitumor efficacy
Q35056286A hyperactive Mpl-based cell growth switch drives macrophage-associated erythropoiesis through an erythroid-megakaryocytic precursor
Q33970635Catch and Release: Photocleavable Cationic Diblock Copolymers as a Potential Platform for Nucleic Acid Delivery
Q28544690In vivo regulation of erythropoiesis by chemically inducible dimerization of the erythropoietin receptor intracellular domain
Q35086136Long-term regulation of genetically modified primary hematopoietic cells in dogs

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