Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae

scientific article published on 15 December 2008

Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.01237-08
P932PMC publication ID2650583
P698PubMed publication ID19075057

P2093author name stringDiane E Kelly
Colin J Jackson
Andrew G S Warrilow
Josie E Parker
Steven L Kelly
Timothy H Marczylo
David C Lamb
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Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosisQ28486631
THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIESQ29616219
Structural changes in cytochrome P-450cam effected by the binding of the enantiomers (1R)-camphor and (1S)-camphor.Q30425797
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Electrostatic control of the substrate access channel in cytochrome P-450cam.Q54019409
Randomised controlled trial of single BCG, repeated BCG, or combined BCG and killed Mycobacterium leprae vaccine for prevention of leprosy and tuberculosis in Malawi. Karonga Prevention Trial GroupQ62490974
Conformational change of cytochrome P450 1A2 induced by sodium chlorideQ71825636
The mutation T315A in Candida albicans sterol 14alpha-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinityQ73084701
Activity of ketoconazole against Mycobacterium tuberculosis in vitro and in the mouse modelQ80651687
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectMycobacterium lepraeQ155891
Mycobacterium smegmatisQ606230
P1104number of pages8
P304page(s)1157-1164
P577publication date2008-12-15
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleIdentification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae
P478volume53

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cites work (P2860)
Q27675293An Enlarged, Adaptable Active Site in CYP164 Family P450 Enzymes, the Sole P450 in Mycobacterium leprae
Q34150915Azole binding properties of Candida albicans sterol 14-alpha demethylase (CaCYP51).
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Q60765405Electron transfer ferredoxins with unusual cluster binding motifs support secondary metabolism in many bacteria
Q34151112Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.
Q46002329In vitro miconazole susceptibility of meticillin-resistant Staphylococcus pseudintermedius and Staphylococcus aureus.
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Q99712430Mutations in the anti-sigma H factor RshA confer resistance to econazole and clotrimazole in Mycobacterium smegmatis
Q48119074Peroxide-dependent oxidation reactions catalyzed by CYP191A1 from Mycobacterium smegmatis.
Q36667269Prothioconazole and prothioconazole-desthio activities against Candida albicans sterol 14-α-demethylase
Q35867465S279 point mutations in Candida albicans Sterol 14-α demethylase (CYP51) reduce in vitro inhibition by fluconazole.
Q38127263The eradication of leprosy: molecular modeling techniques for novel drug discovery
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Q34769112Untangling the multiple monooxygenases of Mycobacterium chubuense strain NBB4, a versatile hydrocarbon degrader

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