Modulation of miRNA activity in human cancer: a new paradigm for cancer gene therapy?

scientific article published on 28 March 2008

Modulation of miRNA activity in human cancer: a new paradigm for cancer gene therapy? is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1038/CGT.2008.8
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/cgt.2008.8
P698PubMed publication ID18369380
P5875ResearchGate publication ID5483910

P2093author name stringJ Nemunaitis
A W Tong
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Functional siRNAs and miRNAs Exhibit Strand BiasQ27861038
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The let-7 microRNA represses cell proliferation pathways in human cellsQ28240833
P68 RNA helicase unwinds the human let-7 microRNA precursor duplex and is required for let-7-directed silencing of gene expressionQ28242438
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MicroRNA signatures in human ovarian cancerQ28249211
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siRNA and miRNA: an insight into RISCsQ28305768
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mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancerQ36103305
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Toxicity in mice expressing short hairpin RNAs gives new insight into RNAiQ36581744
Epigenetics and microRNAsQ36783160
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Argonaute proteins: mediators of RNA silencingQ36845844
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growthQ38298486
MicroRNA expression profiles in head and neck cancer cell linesQ38302158
MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).Q38303663
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MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomasQ40073679
Downregulation of microRNAs-143 and -145 in B-cell malignanciesQ40076849
Regulation of p27Kip1 by miRNA 221/222 in glioblastomaQ40089204
Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cellsQ40123026
The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function.Q40169748
Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125bQ40207487
Antitumor activity of an oncolytic adenovirus-delivered oncogene small interfering RNA.Q40223962
Inhibition of PRL-3 gene expression in gastric cancer cell line SGC7901 via microRNA suppressed reduces peritoneal metastasisQ40250297
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Fibroblast growth factor receptor 3 inhibition by short hairpin RNAs leads to apoptosis in multiple myeloma.Q40422274
Reduced expression of Dicer associated with poor prognosis in lung cancer patients.Q43573248
RNAi in human cells: basic structural and functional features of small interfering RNA.Q44199577
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Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrestQ48078984
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Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues.Q51958786
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.Q52582850
Erk5 is activated and acts as a survival factor in mitosis.Q53541523
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The RNAi revolution.Q55038521
Characterization of colorectal-cancer-related cDNA clones obtained by subtractive hybridization screeningQ56566983
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Literature red in tooth and clawQ74197554
Prognostic value of K-ras mutations, ras oncoprotein, and c-erb B-2 oncoprotein expression in adenocarcinoma of the lungQ74427809
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancerQ29547523
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosisQ29547575
Regulation of the germinal center response by microRNA-155Q29547777
Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAsQ29547837
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumorsQ29614399
MicroRNAs direct rapid deadenylation of mRNAQ29614566
miR-21-mediated tumor growthQ29616149
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancerQ29616316
An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissuesQ29619171
Transcriptional activation of miR-34a contributes to p53-mediated apoptosisQ29619556
Activation of the interferon system by short-interfering RNAsQ29620341
Repression of protein synthesis by miRNAs: how many mechanisms?Q29620361
Augmentation of tumor angiogenesis by a Myc-activated microRNA clusterQ29620726
Illuminating the silence: understanding the structure and function of small RNAsQ29622905
Inducible microRNA expression by an all-in-one episomal vector systemQ30826808
miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1.Q31115813
Regulation of microfilament organization and anchorage-independent growth by tropomyosin 1.Q33706258
Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAsQ33780723
Electroporation-mediated transfer of plasmids to the lung results in reduced TLR9 signaling and inflammationQ34115911
siRNA-mediated gene silencing in vitro and in vivo.Q34150604
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulationQ34212635
Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?Q34455538
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathwaysQ34530552
Expression profiling identifies microRNA signature in pancreatic cancerQ34588109
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinomaQ34647028
MicroRNAs (miR)-221 and miR-222, both overexpressed in human thyroid papillary carcinomas, regulate p27Kip1 protein levels and cell cycleQ34698100
MYCN regulates oncogenic MicroRNAs in neuroblastomaQ34702713
Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissuesQ34997758
MicroRNAs and cancerQ35561593
Oncolytic viral therapiesQ35852258
Oncogenic All1 fusion proteins target Drosha-mediated microRNA processingQ35865083
MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targetsQ35951484
Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugsQ35961201
The role of small RNAs in human diseases: potential troublemaker and therapeutic toolsQ36002359
P433issue6
P921main subjectgene therapyQ213901
cancer gene therapyQ124350675
P304page(s)341-355
P577publication date2008-03-28
P1433published inCancer Gene TherapyQ15763088
P1476titleModulation of miRNA activity in human cancer: a new paradigm for cancer gene therapy?
P478volume15

Reverse relations

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