Antiviral NK cell responses in HIV infection: I. NK cell receptor genes as determinants of HIV resistance and progression to AIDS.

scientific article published on 03 April 2008

Antiviral NK cell responses in HIV infection: I. NK cell receptor genes as determinants of HIV resistance and progression to AIDS. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1189/JLB.0907650
P698PubMed publication ID18388298
P5875ResearchGate publication ID5464847

P2093author name stringAlexandre Iannello
Ali Ahmad
Olfa Debbeche
Suzanne Samarani
P2860cites workActivation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICAQ22010440
An activating immunoreceptor complex formed by NKG2D and DAP10Q22010441
Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cellsQ24290869
Molecular analysis of NTB-A signaling: a role for EAT-2 in NTB-A-mediated activation of human NK cellsQ24300343
IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptorsQ24300426
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptorQ24306696
Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating moleculeQ24314704
X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cellsQ24676168
Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-GQ24678795
Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cellsQ24683311
Activation of NK cells by an endocytosed receptor for soluble HLA-G.Q24813830
KIR2DL4 (CD158d) genotype influences expression and function in NK cellsQ28155876
Recognition of HLA-G by the NK cell receptor KIR2DL4 is not essential for human reproductionQ28180558
The influence of HLA genotype on AIDSQ28202903
KIR2DL4 (CD158d), an NK cell-activating receptor with inhibitory potentialQ28203519
The mechanisms controlling the recognition of tumor- and virus-infected cells by NKp46Q28204339
Cutting edge: induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cellsQ28211347
Expression of killer cell lectin-like receptor G1 on antigen-specific human CD8+ T lymphocytes during active, latent, and resolved infection and its relation with CD57Q28249061
Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donorsQ28259065
Human diversity in killer cell inhibitory receptor genesQ28259075
What is the importance of the immunological synapse?Q28261882
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and CQ28263511
The biology of NKT cellsQ28277482
A soluble form of the MHC class I-specific CD160 receptor is released from human activated NK lymphocytes and inhibits cell-mediated cytotoxicityQ28284183
Cutting edge: lectin-like transcript 1 is a ligand for the CD161 receptorQ28286015
Natural killer type 2 bias in remission of multiple sclerosisQ28359878
KIR/HLA pleiotropism: protection against both HIV and opportunistic infectionsQ28469038
Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptorQ28505934
Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in miceQ28591835
Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clonesQ28610595
MHC class I-independent recognition of NK-activating receptor KIR2DS4Q28610699
Cutting Edge: KIR3DS1, a gene implicated in resistance to progression to AIDS, encodes a DAP12-associated receptor expressed on NK cells that triggers NK cell activationQ28610728
Detection of KIR3DS1 on the cell surface of peripheral blood NK cells facilitates identification of a novel null allele and assessment of KIR3DS1 expression during HIV-1 infectionQ28610733
NK cell recognitionQ29615107
Stepwise cytoskeletal polarization as a series of checkpoints in innate but not adaptive cytolytic killingQ30478310
Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cellsQ32102035
Augmentation of NK cell-mediated cytotoxicity to tumor cells by inhibitory NK cell receptor blockersQ33198527
HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.Q33262230
Natural killer cells in antiviral defense: function and regulation by innate cytokinesQ33652468
Regulation of immune responses through inhibitory receptorsQ33652541
DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the NKG2D receptorQ33911460
Epistasis between mouse Klra and major histocompatibility complex class I loci is associated with a new mechanism of natural killer cell-mediated innate resistance to cytomegalovirus infectionQ33944628
Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1.Q34056087
Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparumQ34078591
A common KIR2DS4 deletion variant in the human that predicts a soluble KIR molecule analogous to the KIR1D molecule observed in the rhesus monkeyQ34160230
Noncytolytic control of viral infections by the innate and adaptive immune responseQ34178107
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.Q34178128
Regulation of the natural killer cell receptor repertoireQ34178144
Receptor-ligand analyses define minimal killer cell Ig-like receptor (KIR) in humansQ44078600
Distinctive NK-cell receptor repertoires sustain high-level constitutive NK-cell activation in HIV-exposed uninfected individualsQ45006277
Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapsesQ45345593
The HLA-B*5703 allele confers susceptibility to the development of spondylarthropathies in Zambian human immunodeficiency virus-infected patients with slow progression to acquired immunodeficiency syndrome.Q45527277
Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages.Q46027985
Interaction between KIR3DL1 and HLA-B*57 supertype alleles influences the progression of HIV-1 infection in a Zambian population.Q46199343
Cutting edge: KIR2DL4 transduces signals into human NK cells through association with the Fc receptor gamma proteinQ46391148
Licensing of natural killer cells by host major histocompatibility complex class I moleculesQ46634172
Genetic variants in nonclassical major histocompatibility complex class I human leukocyte antigen (HLA)-E and HLA-G molecules are associated with susceptibility to heterosexual acquisition of HIV-1.Q46812188
NK cell receptorsQ46858751
Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin productionQ47422836
Functionally active HLA-G polymorphisms are associated with the risk of heterosexual HIV-1 infection in African women.Q47747402
Functional aberrant expression of CCR2 receptor on chronically activated NK cells in patients with TAP-2 deficiencyQ47759184
HIV type 1 Tat protein inhibits interleukin 12 production by human peripheral blood mononuclear cellsQ47815336
Mutual activation of natural killer cells and monocytes mediated by NKp80-AICL interactionQ50335828
Expression of KIR2DL1 on the entire NK cell population: a possible novel immunodeficiency syndrome.Q51026937
T cell- and B cell-independent adaptive immunity mediated by natural killer cells.Q51983250
CD56brightCD16- killer Ig-like receptor- NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation.Q51990042
Induction of CD16+ CD56bright NK cells with antitumour cytotoxicity not only from CD16- CD56bright NK Cells but also from CD16- CD56dim NK cells.Q51996024
Antagonistic effect of NK cells on alternatively activated monocytes: a contribution of NK cells to CTL generation.Q52009896
NKG2D-mediated cytotoxicity toward oligodendrocytes suggests a mechanism for tissue injury in multiple sclerosis.Q52576677
Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.Q52842649
Involvement of human natural killer cells in asthma pathogenesis: natural killer 2 cells in type 2 cytokine predominance.Q52975538
NK cells and human pregnancy--an inflammatory view.Q53007013
The activating NKG2D ligand MHC class I-related chain A transfers from target cells to NK cells in a manner that allows functional consequences.Q53567361
Cutting edge: cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression.Q53903481
Costimulation through NKG2D enhances murine CD8+ CTL function: similarities and differences between NKG2D and CD28 costimulation.Q53924361
Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy.Q54432520
Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals.Q54543693
Cutting Edge: Defective NK Cell Activation in X-Linked Lymphoproliferative DiseaseQ56593901
When killers become helpersQ57083126
Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemiaQ57257278
Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties.Q38320280
Cutting edge: resistance to HIV-1 infection among African female sex workers is associated with inhibitory KIR in the absence of their HLA ligands.Q39104481
Possible roles of KIR2DL4 expression on uNK cells in human pregnancyQ40158701
Allelic expression patterns of KIR3DS1 and 3DL1 using the Z27 and DX9 antibodiesQ40170826
Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells.Q40191693
Identification of distal KIR promoters and transcriptsQ40198207
Release of MICB molecules by tumor cells: mechanism and soluble MICB in sera of cancer patientsQ40280283
Interferon-producing killer dendritic cells provide a link between innate and adaptive immunityQ40323654
A novel dendritic cell subset involved in tumor immunosurveillanceQ40323661
Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillanceQ40382191
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.Q40395254
Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1.Q40419886
NK cells that are activated by CXCL10 can kill dormant tumor cells that resist CTL-mediated lysis and can express B7-H1 that stimulates T cells.Q40493871
LFA-1 contributes an early signal for NK cell cytotoxicity.Q40517797
KIR2DL5 can inhibit human NK cell activation via recruitment of Src homology region 2-containing protein tyrosine phosphatase-2 (SHP-2).Q40547461
Self-reactive memory-phenotype CD8 T cells exhibit both MHC-restricted and non-MHC-restricted cytotoxicity: a role for the T-cell receptor and natural killer cell receptors.Q40548951
Human NKG2F is expressed and can associate with DAP12.Q40556656
Cutting edge: increased NK cell activity in HIV-1-exposed but uninfected Vietnamese intravascular drug usersQ40614184
KIR2DL4 Is an IL-2-Regulated NK Cell Receptor That Exhibits Limited Expression in Humans but Triggers Strong IFN-γ ProductionQ40633231
Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptorsQ40738490
Differential expression of leukocyte receptor complex-encoded Ig-like receptors correlates with the transition from effector to memory CTL.Q40822163
Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40.Q40900792
Natural killer cell-mediated lysis of autologous cells modified by gene therapyQ41853967
Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 geneQ42637807
IL-21 down-regulates NKG2D/DAP10 expression on human NK and CD8+ T cellsQ42678415
Fas-mediated cytotoxicity by freshly isolated natural killer cellsQ42942845
HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infectionQ42986755
Single-stranded RNA derived from HIV-1 serves as a potent activator of NK cellsQ43494949
Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subsetQ43600819
Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progressionQ43769019
Cellular immune responses to HIV.Q34223069
MICA and MICB genes: can the enigma of their polymorphism be resolved?Q34295071
The LLT1 receptor induces IFN-gamma production by human natural killer cellsQ34315735
Strategies for target cell recognition by natural killer cellsQ34341441
Human natural killer cell receptors and co-receptorsQ34341459
IL-15 and HIV infection: lessons for immunotherapy and vaccinationQ34434319
Dicing and slicing: the core machinery of the RNA interference pathwayQ34458132
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunctionQ34570127
DAP12: an adapter protein with dual functionalityQ34581211
Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effectQ34802287
Human natural killer cell deficiencies and susceptibility to infectionQ35035745
TGFbeta promotes conversion of CD16+ peripheral blood NK cells into CD16- NK cells with similarities to decidual NK cellsQ35652432
HIV's evasion of host's NK cell response and novel ways of its countering and boosting anti-HIV immunityQ35716737
Synergy or independence? Deciphering the interaction of HLA Class I and NK cell KIR alleles in early HIV-1 disease progressionQ35753686
HLA class I-specific inhibitory receptors in human T lymphocytes: interleukin 15-induced expression of CD94/NKG2A in superantigen- or alloantigen-activated CD8+ T cells.Q35798486
Role of NK and NKT cells in the immunopathogenesis of HCV-induced hepatitis.Q35817615
A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC moleculesQ35847508
Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosityQ35865986
Different checkpoints in human NK-cell activationQ35941923
Immunogenetics of killer cell immunoglobulin-like receptorsQ35988375
Associations between KIR epitope combinations expressed by HLA-B/-C haplotypes found in an HIV-1 infected study population may influence NK mediated immune responsesQ35988436
Natural killer cells trigger differentiation of monocytes into dendritic cellsQ36007747
HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2AQ36065870
Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway.Q36191417
Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector functionQ36228467
CD11cloB220+ interferon-producing killer dendritic cells are activated natural killer cellsQ36229123
Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypesQ36229197
Viral strategies for evading antiviral cellular immune responses of the hostQ36276589
NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80.Q36363753
Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cellsQ36375639
The direct binding of a p58 killer cell inhibitory receptor to human histocompatibility leukocyte antigen (HLA)-Cw4 exhibits peptide selectivityQ36377146
Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive successQ36399286
Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysisQ36400442
Natural killer (NK) cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cellsQ36401340
Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells.Q36403556
IL-18-induced CD83+CCR7+ NK helper cellsQ36403560
How do natural killer cells find self to achieve tolerance?Q36424804
The killer immunoglobulin-like receptor gene cluster: tuning the genome for defenseQ36528852
Regulation of class I major histocompatibility complex receptor expression in natural killer cells: one promoter is not enough!Q36652145
NK cell regulation by SLAM family receptors and SAP-related adaptersQ36652149
Bone marrow versus thymic pathways of natural killer cell developmentQ36652153
Human natural killer cell developmentQ36652161
Activation, coactivation, and costimulation of resting human natural killer cellsQ36652166
Activation and self-tolerance of natural killer cellsQ36652183
KIR and disease: a model system or system of models?Q36652201
Natural killer cells in viral infection: more than just killers.Q36652221
Intercellular transfer of cell-surface proteins is common and can affect many stages of an immune responseQ36732268
NKT cells: T lymphocytes with innate effector functionsQ36788766
Identification of bidirectional promoters in the human KIR genesQ38304437
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectHIV/AIDSQ12199
HIVQ15787
P304page(s)1-26
P577publication date2008-04-03
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleAntiviral NK cell responses in HIV infection: I. NK cell receptor genes as determinants of HIV resistance and progression to AIDS.
P478volume84

Reverse relations

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