Role of the growth-associated protein B-50/GAP-43 in neuronal plasticity

scientific article published on January 1, 1991

Role of the growth-associated protein B-50/GAP-43 in neuronal plasticity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/BF02935540
P953full work available at URLhttp://link.springer.com/article/10.1007/BF02935540/fulltext.html
http://link.springer.com/content/pdf/10.1007/BF02935540
http://link.springer.com/content/pdf/10.1007/BF02935540.pdf
P698PubMed publication ID1840422

P2093author name stringW. H. Gispen
P. Schotman
P. N. De Graan
A. B. Oestreicher
L. H. Schrama
H. B. Nielander
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Molecular characterization of a karyophilic, histone-binding protein: cDNA cloning, amino acid sequence and expression of nuclear protein N1/N2 of Xenopus laevisQ24531874
Comparison of the immunocytochemical distribution of the phosphoprotein B-50 in the cerebellum and hippocampus of immature and adult rat brainQ48333595
Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growthQ48343019
A radioimmunoassay for the phosphoprotein B-50: distribution in rat brainQ48351502
Phosphoprotein B-50 and phosphoinositides in brain synaptic plasma membranes: a possible feedback relationshipQ48382924
Resolution of rat brain synaptic phosphoprotein B-50 into multiple forms by two-dimensional electrophoresis: evidence for multisite phosphorylationQ48503508
Presynaptic localization of B-50 phosphoprotein: the (ACTH)-sensitive protein kinase substrate involved in rat brain polyphosphoinositide metabolismQ48509685
Purification of a novel calmodulin-binding protein from bovine cerebral cortex membranesQ48737206
Phosphorylation of B-50 Protein by Calcium-Activated, Phospholipid-Dependent Protein Kinase and B-50 Protein KinaseQ48752641
Immunoreactive GAP-43 in the neuropil of adult rat neostriatum: localization in unmyelinated fibers, axon terminals, and dendritic spinesQ48832971
Neurogranin: immunocytochemical localization of a brain-specific protein kinase C substrateQ48843250
Mutation of serine 41 in the neuron-specific protein B-50 (GAP-43) prohibits phosphorylation by protein kinase C.Q48890836
Gene expression of a neuronal growth-associated protein, GAP-43, in the paraganglionic carotid body as well as in the autonomic ganglia of normal adult ratsQ48896066
Abnormal retinal projections alter GAP-43 patterns in the diencephalonQ48896607
Long-term potentiation of the perforant path in vivo is associated with increased glutamate releaseQ48933518
Neuroplasticity in the olfactory system: differential effects of central and peripheral lesions of the primary olfactory pathway on the expression of B-50/GAP43 and the olfactory marker proteinQ49011149
G0 is a major growth cone protein subject to regulation by GAP-43.Q49017518
Evidence for a relationship between B-50 (GAP-43) and [3H]noradrenaline release in rat brain synaptosomesQ49057431
Chicken growth-associated protein GAP-43 is tightly bound to the actin-rich neuronal membrane skeletonQ49087085
Aspects of Protein Phosphorylation in the Nervous System with Particular Reference to Synaptic TransmissionQ49102772
Changes in the distribution of GAP-43 during the development of neuronal polarityQ49123816
Dephosphorylation of neuromodulin by calcineurin.Q50886532
Redistribution of GAP-43 during growth cone developmentin vitro; immunocytochemical studiesQ52237977
Cloning and Characterization of the Rat Gene Encoding GAP-43.Q52242626
Developmental expression of the amyloid precursor protein, growth-associated protein 43, and somatostatin in normal and trisomy 16 mice.Q52244848
The neuronal growth-associated protein GAP-43 (B-50, F1): neuronal specificity, developmental regulation and regional distribution of the human and rat mRNAs.Q52255930
Genes-in-pieces revisited.Q53728552
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Direct relation of long-term synaptic potentiation to phosphorylation of membrane protein F1, a substrate for membrane protein kinase C.Q48265350
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Cloning of complementary DNA for GAP-43, a neuronal growth-related proteinQ28566187
The interactions of the brain-specific calmodulin-binding protein kinase C substrate, neuromodulin (GAP 43), with membrane phospholipidsQ28566354
B-50/GAP43 Expression Correlates with Process Outgrowth in the Embryonic Mouse Nervous SystemQ28588077
A membrane phosphoprotein associated with neural development, axonal regeneration, phospholipid metabolism, and synaptic plasticityQ29306548
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Rapid changes in the distribution of GAP-43 correlate with the expression of neuronal polarity during normal development and under experimental conditionsQ30442298
Growth-associated protein GAP-43 is expressed selectively in associative regions of the adult human brainQ33575803
The 43-kDa neuronal growth-associated protein (GAP-43) is present in plasma membranes of rat astrocytesQ33666225
GAP-43 in growth cones is associated with areas of membrane that are tightly bound to substrate and is a component of a membrane skeleton subcellular fractionQ33836478
Purification of the growth-associated protein GAP-43 by reversed phase chromatography: amino acid sequence analysis and cDNA identificationQ33843706
Regulation of free calmodulin levels by neuromodulin: neuron growth and regenerationQ33881441
Subtractive cDNA cloning of RC3, a rodent cortex-enriched mRNA encoding a novel 78 residue proteinQ34153989
Transfection of PC12 cells with the human GAP-43 gene: effects on neurite outgrowth and regenerationQ34182089
The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterizationQ34352167
Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth conesQ35606612
Axonally transported proteins associated with axon growth in rabbit central and peripheral nervous systemsQ36204698
Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43.Q36220186
Regulation of immunoreactive GAP-43 expression in rat cortical macroglia is cell type specificQ36223283
A membrane-targeting signal in the amino terminus of the neuronal protein GAP-43.Q36223437
Neuromodulin (GAP43): a neuronal protein kinase C substrate is also present in 0-2A glial cell lineage. Characterization of neuromodulin in secondary cultures of oligodendrocytes and comparison with the neuronal antigenQ36223616
Identification, localization, and primary structure of CAP-23, a particle-bound cytosolic protein of early developmentQ36224316
The NGF-inducible SCG10 mRNA encodes a novel membrane-bound protein present in growth cones and abundant in developing neuronsQ36444428
Primary structure and mRNA localization of protein F1, a growth-related protein kinase C substrate associated with synaptic plasticityQ36456307
Monoclonal antibodies show that kinase C phosphorylation of GAP-43 during axonogenesis is both spatially and temporally restricted in vivoQ36529333
Protein kinase C substrate B-50 (GAP-43) and neurotransmitter releaseQ36546239
Transmitter release: target of regulation by protein kinase C?Q36546242
Ionic Channels and Their Regulation by G Protein SubunitsQ36570869
Expression of the growth- and plasticity-associated neuronal protein, GAP-43, in PC12 pheochromocytoma cellsQ37129204
B-50 (GAP-43): Biochemistry and Functional Neurochemistry of a Neuron-Specific PhosphoproteinQ37164949
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Calcium/calmodulin-dependent protein kinase II.Q37899144
How calmodulin binds its targets: sequence independent recognition of amphiphilic alpha-helicesQ37921960
GAP-43--what does it do in the growth cone?Q38208874
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Expression of cDNAs encoding wild-type and mutant neuromodulins in Escherichia coli: comparison with the native protein from bovine brainQ38343401
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Axonal growth-associated proteinsQ38613255
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4-Aminopyridine stimulates B-50 (GAP-43) phosphorylation in rat synaptosomesQ41198368
B-50/GAP43 is localized at the cytoplasmic side of the plasma membrane in developing and adult rat pyramidal tractQ41267264
Modulation of B-50 phosphorylation and polyphosphoinositide metabolism in synaptic plasma membranes by protein kinase C, phorbol diesters and ACTH.Q41335465
Protein kinase C phosphorylates a 47 Mr protein (F1) directly related to synaptic plasticityQ41393944
Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cellsQ41541134
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B-50 phosphorylation, protein kinase C and the induction of excessive grooming behavior in the rat.Q41834630
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Ultrastructural localization of adrenocorticotrophic hormone and the phosphoprotein B-50/growth-associated protein 43 in freeze-substituted, Lowicryl HM20-embedded mesencephalic central gray substance of the ratQ41867673
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GAP-43 in the cat visual cortex during postnatal development.Q43563825
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Protein kinase C activity and substrate (F1/GAP-43) phosphorylation in developing cat visual cortexQ44270805
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The growth-associated protein GAP-43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injuryQ45351455
Phosphoprotein B-50 in nerve growth cones from fetal rat brainQ45806104
Comparison between the neural acidic proteins B-50 and F1.Q45899126
The expression of B-50/GAP-43 during development of rat spinal neurons in culture is regulated by interneuronal contactQ46441978
ACTH, cyclic nucleotides, and brain protein phosphorylation in vitroQ47712853
The protein kinase C phosphosite(s) in B-50 (GAP-43) are confined to 15K phosphofragments produced by Staphylococcus aureus V8 proteaseQ47796329
Anatomical distribution of the growth-associated protein GAP-43/B-50 in the adult rat brainQ48134430
Amino acid sequence of P-57, a neurospecific calmodulin-binding proteinQ48183044
The expression and distribution of the microtubule-associated proteins tau and microtubule-associated protein 2 in hippocampal neurons in the rat in situ and in cell cultureQ48201931
Distribution and phosphorylation of the growth-associated protein GAP-43 in regenerating sympathetic neurons in cultureQ68074236
Binding of the neuronal protein B-50, but not the metabolite B-60, to calmodulinQ68408351
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Corticotropin (ACTH) inhibits the specific proteolysis of the neuronal phosphoprotein B-50/GAP-43Q68495226
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Localization of the growth-associated phosphoprotein GAP-43 (B-50, F1) in the human cerebral cortexQ69057890
Expression of GAP-43, a rapidly transported growth-associated protein, and class II beta tubulin, a slowly transported cytoskeletal protein, are coordinated in regenerating neuronsQ69183304
Protein kinase C substrates from bovine brain. Purification and characterization of neuromodulin, a neuron-specific calmodulin-binding proteinQ69292967
Phosphorylation-regulated calmodulin binding to a prominent cellular substrate for protein kinase CQ69361596
Microheterogeneity of the growth-associated neuronal protein B-50 (GAP-43). Contribution of phosphorylation by protein kinase CaQ69448166
A developmentally regulated chicken neuronal protein associated with the cortical cytoskeletonQ69483488
Identification of an adipocyte protein that binds to calmodulin in the absence of Ca2+ and is phosphorylated in response to insulin and tumor-promoting phorbol estersQ69503340
The role of protein kinase C in long-term potentiation: a testable modelQ69548745
Axonal transport and localization of B-50/GAP-43-like immunoreactivity in regenerating sciatic and facial nerves of the ratQ69581483
GAP-43 gene expression during development: persistence in a distinctive set of neurons in the mature central nervous systemQ69609942
Evidence for a single protein kinase C-mediated phosphorylation site in rat brain protein B-50Q69788356
Ultrastructural immunocytochemical localization of B-50/GAP43, a protein kinase C substrate, in isolated presynaptic nerve terminals and neuronal growth conesQ69788408
B-50 phosphorylation and polyphosphoinositide metabolism in nerve growth cone membranesQ69826220
The two major phosphoproteins in growth cones are probably identical to two protein kinase C substrates correlated with persistence of long-term potentiationQ69949148
Protein fatty acid acylation in developing cortical neuronsQ69966136
Demonstration by phase-partitioning in Triton X-114 solutions that phosphoprotein B-50 (F-1) from rat brain is an integral membrane proteinQ70026360
Regulation of calmodulin binding to P-57. A neurospecific calmodulin binding proteinQ70028194
Identification and characterization of the calmodulin-binding domain of neuromodulin, a neurospecific calmodulin-binding proteinQ70054656
The growth-associated neuronal phosphoprotein B-50: improved purification, partial primary structure, and characterization and localization of proteolysis productsQ70064490
Stimulation by GTP-binding proteins (Gi, Go) of partially purified phospholipase C activity from human platelet membranesQ70353435
Increased transport of 44,000- to 49,000-dalton acidic proteins during regeneration of the goldfish optic nerve: a two-dimensional gel analysisQ71073622
Purification and Some Characteristics of an ACTH-Sensitive Protein Kinase and Its Substrate Protein in Rat Brain MembranesQ72853597
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P433issue2-4
P407language of work or nameEnglishQ1860
P921main subjectneuroplasticityQ849491
neurologyQ83042
P304page(s)61-85
P577publication date1991-01-01
P1433published inMolecular NeurobiologyQ15716645
P1476titleRole of the growth-associated protein B-50/GAP-43 in neuronal plasticity
P478volume5