N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG.

scientific article published on 21 January 2009

N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M805877200
P932PMC publication ID2659187
P698PubMed publication ID19164298

P50authorWayne I. LencerQ38328140
Richard S BlumbergQ88194386
Timothy KuoQ122928629
Masaru YoshidaQ122928636
Victoria G AvesonQ122928644
P2093author name stringSteven M Claypool
Eric J de Muinck
Takashi Nagaishi
P2860cites workFunctional reconstitution of human FcRn in Madin-Darby canine kidney cells requires co-expressed human beta 2-microglobulinQ24645189
Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent bindingQ27631600
Crystal structure of the complex of rat neonatal Fc receptor with FcQ27730776
Structural basis of pH-dependent antibody binding by the neonatal Fc receptorQ27748905
Site-directed mutagenesis by overlap extension using the polymerase chain reactionQ27860503
Tryptophan- and dileucine-based endocytosis signals in the neonatal Fc receptorQ31628526
Glycans in post-Golgi apical targeting: sorting signals or structural props?Q33688015
Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodiesQ34102657
Generation of mutated variants of the human form of the MHC class I-related receptor, FcRn, with increased affinity for mouse immunoglobulin G.Q34230234
Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptorQ35103852
Apical sorting of hepatitis B surface antigen (HBsAg) is independent of N-glycosylation and glycosylphosphatidylinositol-anchored protein segregationQ36023487
The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cellsQ36274330
Ca2+-dependent calmodulin binding to FcRn affects immunoglobulin G transport in the transcytotic pathwayQ36325938
Dependence of antibody-mediated presentation of antigen on FcRnQ36756942
FcRn: the neonatal Fc receptor comes of age.Q36912134
Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fcgamma-receptor.Q37220781
Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.Q37334251
Bidirectional transcytosis of IgG by the rat neonatal Fc receptor expressed in a rat kidney cell line: a system to study protein transport across epithelia.Q40895726
Nonvectorial surface transport, endocytosis via a Di-leucine-based motif, and bidirectional transcytosis of chimera encoding the cytosolic tail of rat FcRn expressed in Madin-Darby canine kidney cellsQ40966100
N-glycans as apical sorting signals in epithelial cellsQ41273218
Effects of mutations in potential phosphorylation sites on transcytosis of FcRn.Q43561957
The transmission of immune globulins from the mother to the foetal and newborn youngQ43643314
Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells.Q47365627
Net absorption of IgG via FcRn-mediated transcytosis across rat alveolar epithelial cell monolayersQ47415370
IgG transport across mucosal barriers by neonatal Fc receptor for IgG and mucosal immunityQ57179983
Cloning and expression of the neonatal rat intestinal Fc receptor, a major histocompatibility complex class I antigen homologQ69319871
Immunoglobulin G receptors of intestinal brush borders from neonatal ratsQ72784864
IgG binding and expression of its receptor in rat intestine during postnatal developmentQ73392260
Conferring the binding properties of the mouse MHC class I-related receptor, FcRn, onto the human ortholog by sequential rounds of site-directed mutagenesisQ81255549
P4510describes a project that usesImageJQ1659584
P433issue13
P407language of work or nameEnglishQ1860
P304page(s)8292-8300
P577publication date2009-01-21
P1433published inJournal of Biological ChemistryQ867727
P1476titleN-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG.
P478volume284

Reverse relations

cites work (P2860)
Q34907420Abundant intracellular IgG in enterocytes and endoderm lacking FcRn
Q34783912Bovine FcRn-mediated human immunoglobulin G transfer across the milk-blood barrier in transgenic mice
Q37597698Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.
Q28732874Characterization of the rabbit neonatal Fc receptor (FcRn) and analyzing the immunophenotype of the transgenic rabbits that overexpresses FcRn
Q57197951Clinical chemistry of human FcRn transgenic mice
Q35624937Evidence that FcRn mediates the transplacental passage of maternal IgE in the form of IgG anti-IgE/IgE immune complexes
Q26799266Fc glycans of therapeutic antibodies as critical quality attributes
Q26822421Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics
Q35670904FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin.
Q38239281FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions
Q35552397Genetically engineered humanized mouse models for preclinical antibody studies
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Q34595009HIV-1 envelope glycan moieties modulate HIV-1 transmission
Q33556839Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury
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Q36514911Proximal Tubules Have the Capacity to Regulate Uptake of Albumin
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Q28080589Targeting FcRn for the modulation of antibody dynamics
Q92239387The Neonatal Fc Receptor (FcRn): A Misnomer?
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