Plasma membrane proteomics identifies biomarkers associated with MMSET overexpression in T(4;14) multiple myeloma

scientific article published on July 2013

Plasma membrane proteomics identifies biomarkers associated with MMSET overexpression in T(4;14) multiple myeloma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.1049
P932PMC publication ID3759662
P698PubMed publication ID23900284
P5875ResearchGate publication ID253648335

P2093author name stringZhigang Xie
Jayantha Gunaratne
Gaofeng Huang
Shaw Cheng Liu
Wee Joo Chng
Lip Lee Cheong
Walter P Blackstock
Tze Loong Koh
P2860cites workActivation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 familyQ24291883
Multiple myelomaQ24655964
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressorQ40031496
Combined affinity labelling and mass spectrometry analysis of differential cell surface protein expression in normal and prostate cancer cellsQ40399386
p53-regulated transcriptional program associated with genotoxic stress-induced apoptosisQ40579357
Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity.Q41087450
A new format of bispecific antibody: highly efficient heterodimerization, expression and tumor cell lysis.Q51547306
A global expression-based analysis of the consequences of the t(4;14) translocation in myeloma.Q52858755
Functional and quantitative proteomics using SILACQ57369727
Multiple myelomaQ77292034
In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expressionQ78410148
Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patientsQ24670250
A unique mRNA initiated within a middle intron of WHSC1/MMSET encodes a DNA binding protein that suppresses human IL-5 transcriptionQ28142350
Chromosome translocations in multiple myelomaQ28199347
A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcriptQ28214995
The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcriptsQ28286552
Strategies for silencing human disease using RNA interferenceQ28288535
A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC)Q28296386
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantificationQ29547200
In-gel digestion for mass spectrometric characterization of proteins and proteomesQ29547583
Drug-target networkQ29614447
Molecular and functional characterization of a CS1 (CRACC) splice variant expressed in human NK cells that does not contain immunoreceptor tyrosine-based switch motifsQ31112284
SLAM-family receptors: immune regulators with or without SAP-family adaptorsQ33693795
Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cellsQ33948015
Cloning, genomic organization, alternative transcripts and expression analysis of CD99L2 , a novel paralog of human CD99, and identification of evolutionary conserved motifsQ34191933
Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.Q34210005
Cell cycle-mediated drug resistance: an emerging concept in cancer therapy.Q34328725
The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.Q34568855
Membrane proteins and membrane proteomicsQ34657071
CS1 (CRACC, CD319) induces proliferation and autocrine cytokine expression on human B lymphocytesQ34689964
Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myelomaQ35170921
Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expressionQ35568362
CS1, a potential new therapeutic antibody target for the treatment of multiple myelomaQ35610286
Molecular pathogenesis and a consequent classification of multiple myelomaQ36254602
The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.Q36384699
NK cell regulation by SLAM family receptors and SAP-related adaptersQ36652149
Ten years and counting: so what do we know about t(4;14)(p16;q32) multiple myeloma.Q36654607
Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieuQ36835070
Targeted delivery of small interfering RNA: approaching effective cancer therapiesQ37100611
Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discoveryQ37119996
Membrane-tethered proteins for basic research, imaging, and therapy.Q37164168
IL-6 trans-signaling system in intra-amniotic inflammation, preterm birth, and preterm premature rupture of the membranesQ37238620
Characterization of MYC translocations in multiple myeloma cell linesQ37331601
Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myelomaQ37357340
Proteomic identification of differentially expressed plasma membrane proteins in renal cell carcinoma by stable isotope labelling of a von Hippel-Lindau transfectant cell line modelQ39865719
MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells.Q39908262
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectbiomarkerQ864574
overexpressionQ61643320
P304page(s)1008-1018
P577publication date2013-07-01
P1433published inOncotargetQ1573155
P1476titlePlasma membrane proteomics identifies biomarkers associated with MMSET overexpression in T(4;14) multiple myeloma
P478volume4

Reverse relations

cites work (P2860)
Q58582611Clinical impact of serum soluble SLAMF7 in multiple myeloma
Q55310350Elotuzumab for the Treatment of Relapsed or Refractory Multiple Myeloma, with Special Reference to its Modes of Action and SLAMF7 Signaling.
Q48169937Immunopathogenesis and immunotherapy of multiple myeloma.
Q92014013Immunotherapy for Multiple Myeloma
Q47626310Integrated powered density: Screening ultrahigh dimensional covariates with survival outcomes.
Q93336711MMSET I acts as an oncoprotein and regulates GLO1 expression in t(4;14) multiple myeloma cells
Q38850840MMSET regulates expression of IRF4 in t(4;14) myeloma and its silencing potentiates the effect of bortezomib
Q33908640MMSET: role and therapeutic opportunities in multiple myeloma.
Q59136966Mechanisms of NK Cell Activation and Clinical Activity of the Therapeutic SLAMF7 Antibody, Elotuzumab in Multiple Myeloma
Q91814085Metabolic, Anti-apoptotic and Immune Evasion Strategies of Primary Human Myeloma Cells Indicate Adaptations to Hypoxia
Q89565340Molecular basis of clonal evolution in multiple myeloma
Q92266478Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7
Q28076147Spotlight on elotuzumab in the treatment of multiple myeloma: the evidence to date
Q40968068Streamlined Membrane Proteome Preparation for Shotgun Proteomics Analysis with Triton X-100 Cloud Point Extraction and Nanodiamond Solid Phase Extraction
Q36169794The antigenic landscape of multiple myeloma: mass spectrometry (re)defines targets for T-cell-based immunotherapy

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