Drosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration

scientific article published on 30 July 2013

Drosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/CR.2013.101
P932PMC publication ID3760623
P698PubMed publication ID23896988

P50authorFangfang RenQ122852864
P2093author name stringY Tony Ip
Qing Shi
Jin Jiang
Yongbin Chen
Huaqi Jiang
Alice Jiang
P2860cites workMaintaining tissue homeostasis: dynamic control of somatic stem cell activityQ26852586
Myc deletion rescues Apc deficiency in the small intestineQ28591197
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancerQ29614594
dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cellsQ33707393
Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut.Q52746350
c-Myc is required for the formation of intestinal crypts but dispensable for homeostasis of the adult intestinal epitheliumQ33925138
Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural developmentQ33943141
Characterization of a dominant-active STAT that promotes tumorigenesis in Drosophila.Q34037299
Characterization of midgut stem cell- and enteroblast-specific Gal4 lines in drosophila.Q34217749
The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration programQ34244244
The Hippo tumor suppressor pathway regulates intestinal stem cell regenerationQ34342510
The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regenerationQ34342516
Hippo signaling regulatesDrosophilaintestine stem cell proliferation through multiple pathwaysQ34396983
EGF signaling regulates the proliferation of intestinal stem cells in DrosophilaQ34592495
Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cellsQ35196044
Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundanceQ35621419
Inducible progenitor-derived Wingless regulates adult midgut regeneration in DrosophilaQ36296267
Drosophila growth and development in the absence of dMyc and dMntQ36569851
The Myc oncoprotein as a therapeutic target for human cancerQ36578165
The ins and outs of MYC regulation by posttranslational mechanismsQ36599161
Tissue damage-induced intestinal stem cell division in DrosophilaQ37137625
Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinasesQ37233375
Reflecting on 25 years with MYC.Q37333643
Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in DrosophilaQ37379590
Myc's other life: stem cells and beyondQ37616350
Drosophila Myc.Q37621011
Intestinal stem cell function in Drosophila and miceQ38011457
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size controlQ40015415
Suppressor of cytokine signaling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colonQ40171665
Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growthQ40394995
EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in DrosophilaQ41871121
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanismsQ41980171
Evidence for a Growth-Stabilizing Regulatory Feedback Mechanism between Myc and Yorkie, the Drosophila Homolog of YapQ42023045
Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgutQ42077813
Warts and Yorkie Mediate Intestinal Regeneration by Influencing Stem Cell ProliferationQ42109247
Pointed and Tramtrack69 establish an EGFR-dependent transcriptional switch to regulate mitosis.Q44226373
Adenomatous polyposis coli regulates Drosophila intestinal stem cell proliferationQ44856599
Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferationQ45097924
Drosophila myc regulates organ size by inducing cell competitionQ47071644
dMyc transforms cells into super-competitorsQ47072112
Identification of a Stat gene that functions in Drosophila developmentQ48066308
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development.Q50777362
Ras pathway specificity is determined by the integration of multiple signal-activated and tissue-restricted transcription factors.Q52163714
EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells.Q52609447
Evidence that stem cells reside in the adult Drosophila midgut epithelium.Q52663260
The adult Drosophila posterior midgut is maintained by pluripotent stem cells.Q52663264
P433issue9
P921main subjectDrosophilaQ312154
P304page(s)1133-1146
P577publication date2013-07-30
P1433published inCell ResearchQ1524018
P1476titleDrosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration
P478volume23

Reverse relations

cites work (P2860)
Q90391176A novel transcriptional cascade is involved in Fzr-mediated endoreplication
Q36300520Bunched and Madm Function Downstream of Tuberous Sclerosis Complex to Regulate the Growth of Intestinal Stem Cells in Drosophila
Q33608508Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling
Q92147843DSS-induced damage to basement membranes is repaired by matrix replacement and crosslinking
Q34873737Drosophila Myc: A master regulator of cellular performance
Q93014038Dual role of FGF in proliferation and endoreplication of Drosophila tracheal adult progenitor cells
Q33701814EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration
Q36247611Effect of Varroa destructor, Wounding and Varroa Homogenate on Gene Expression in Brood and Adult Honey Bees
Q33796239Gene expression profiling identifies the zinc-finger protein Charlatan as a regulator of intestinal stem cells in Drosophila
Q35184451Injury-stimulated Hedgehog signaling promotes regenerative proliferation of Drosophila intestinal stem cells
Q41677971Injury-stimulated and self-restrained BMP signaling dynamically regulates stem cell pool size during Drosophila midgut regeneration.
Q37627722Intestinal epithelium-derived BMP controls stem cell self-renewal in Drosophila adult midgut
Q38823324Intestinal stem cell response to injury: lessons from Drosophila
Q57466918Lessons from Drosophila Pointed, an ETS family transcription factor and key nuclear effector of the RTK signaling pathway
Q101403046Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal permeability and survival in Drosophila
Q51555253Nurr1 promotes intestinal regeneration after ischemia/reperfusion injury by inhibiting the expression of p21 (Waf1/Cip1).
Q48105753Ras/ERK-signalling promotes tRNA synthesis and growth via the RNA polymerase III repressor Maf1 in Drosophila
Q60053979Spen limits intestinal stem cell self-renewal
Q52775231Src kinase function controls progenitor cell pools during regeneration and tumor onset in the Drosophila intestine.
Q38826172The Hippo pathway in intestinal regeneration and disease
Q34451079The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila
Q91198207The transcription factor FoxM1 activates Nurr1 to promote intestinal regeneration after ischemia/reperfusion injury

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