Oxidation of ethanol in the rat brain and effects associated with chronic ethanol exposure

scientific article published on 12 August 2013

Oxidation of ethanol in the rat brain and effects associated with chronic ethanol exposure is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2013PNAS..11014444W
P356DOI10.1073/PNAS.1306011110
P932PMC publication ID3761635
P698PubMed publication ID23940368
P5875ResearchGate publication ID255790978

P2093author name stringJie Wang
Lihong Jiang
Kevin L Behar
Robin A de Graaf
Graeme F Mason
Hongying Du
Xiaoxian Ma
P2860cites workEthanol as a prodrug: brain metabolism of ethanol mediates its reinforcing effectsQ22242357
Enhancement of nuclear magnetic resonance signals by polarization transferQ29011338
Acute alcohol intoxication decreases glucose metabolism but increases acetate uptake in the human brainQ30445186
Regional metabolite levels and turnover in the awake rat brain under the influence of nicotineQ30475326
Distribution and kinetics of ethanol metabolism in rat brainQ48339038
Enzymatic production of acetaldehyde from ethanol in rat brain tissueQ48423521
Continuous osmotic minipump infusion of alcohol into brain decreases brain [Mg2+] and brain bioenergetics and enhances susceptibility to hemorrhagic stroke: an in vivo 31P-NMR studyQ48526112
Changes in brain alcohol dehydrogenase activity during chronic ethanol ingestion and withdrawalQ48577568
Catalase mediates acetaldehyde formation from ethanol in fetal and neonatal rat brainQ48623562
Characterization of the production of acetaldehyde by astrocytes in culture after ethanol exposureQ48623591
Ethanol metabolism in the brain.Q48624155
Carrier-mediated blood-brain barrier transport of short-chain monocarboxylic organic acidsQ48654245
(2- 14 C) ethanol as a precursor of glutamine, glutamate, -aminobutyric acid and aspartate in hamster brain in vivoQ48739281
Immunohistochemical localization of alcohol dehydrogenase in human kidney, endocrine organs and brainQ48834273
Regional distribution of ethanol-inducible cytochrome P450 IIE1 in the rat central nervous systemQ49161438
Effect of ethanol on glucose and amino acid metabolism in brainQ51119984
Brain aldehyde dehydrogenase. Localization, purification, and properties.Q51230662
EFFECT OF ETHANOL AND ACETALDEHYDE ON LIVER AND BRAIN MONOAMINE OXIDASE.Q51277208
Effects of ethanol on enforced spatial variability in the 8-arm radial maze.Q52283762
Sensitivity enhancement in nitrogen-15 NMR: polarization transfer using the INEPT pulse sequenceQ56812952
Pharmacokinetic Imaging of11C Ethanol with PET in Eight Patients with Hepatocellular Carcinomas Who Were Scheduled for Treatment with Percutaneous Ethanol InjectionQ60652409
Studies on metabolic tolerance to alcohol, hepatomegaly and alcoholic liver diseaseQ66972152
[Aldehyde dehydrogenase activity in the barrier brain structures]Q67926475
Immunocytochemistry of alcohol dehydrogenase in the rat central nervous systemQ69562097
The development of metabolic tolerance in the alcohol-preferring P rats: comparison of forced and free-choice drinking of ethanolQ69673561
In vivo acetaldehyde in the brain of the rat treated with ethanolQ71154323
Enzymic catalysis of the accumulation of acetaldehyde from ethanol in human prenatal cephalic tissues: evaluation of the relative contributions of CYP2E1, alcohol dehydrogenase, and catalase/peroxidasesQ72995429
Recovery of high-integrity mRNA from brains of rats killed by high-energy focused microwave irradiationQ73258515
Evaluation of cerebral acetate transport and metabolic rates in the rat brain in vivo using 1H-[13C]-NMRQ30478428
Association of alcohol in brain injury, headaches, and stroke with brain-tissue and serum levels of ionized magnesium: a review of recent findings and mechanisms of actionQ30583646
Expression of Catalase mRNA and Protein in Adult Rat Brain: Detection by Nonradioactive In Situ Hybridization with Signal Amplification by Catalyzed Reporter Deposition (ISH–CARD) and Immunohistochemistry (IHC)/Immunofluorescence (IF)Q30933297
Ethanol metabolism and production of free acetate in the human liverQ34020001
The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat.Q34062645
Alterations in brain glucose utilization accompanying elevations in blood ethanol and acetate concentrations in the ratQ34216411
Involvement of acetaldehyde in alcohol addictionQ34513255
Microinjections of acetaldehyde or salsolinol into the posterior ventral tegmental area increase dopamine release in the nucleus accumbens shellQ34695455
Role of variability in explaining ethanol pharmacokinetics: research and forensic applicationsQ35029490
Desipramine blocks alcohol-induced anxiety- and depressive-like behaviors in two rat strainsQ35400968
Alcohol, oxidative stress, and free radical damageQ35947149
An ethanol vapor chamber system for small animalsQ36035639
In vivo detection of intermediate metabolic products of [1-(13) C]ethanol in the brain using (13) C MRSQ36104403
Magnesium homeostasis in mammalian cells.Q36664315
Increased brain uptake and oxidation of acetate in heavy drinkersQ36733426
Oxidation of ethanol in the brain and its consequencesQ36918867
Studying alcohol elimination using the alcohol clamp method.Q36918874
Recurrent antecedent hypoglycemia alters neuronal oxidative metabolism in vivoQ37193674
Putative role of brain acetaldehyde in ethanol addictionQ37362242
Effect of ethanol on cytochrome P450 in the rat brainQ37558505
1H-Observe/13C-decouple spectroscopic measurements of lactate and glutamate in the rat brain in vivoQ37680300
Notes on synaptic vesicles and related structures, endoplasmic reticulum, lysosomes and peroxisomes in nervous tissue and the adrenal medullaQ39926816
Metabolism of ethanol and acetaldehyde by the isolated perfused rat brainQ40312980
Role of acetaldehyde in the actions of ethanol on the brain--a reviewQ40947670
Influence of Chronic Ethanol Vapor Inhalation on Hepatic Parenchymal and Kupffer Cell FunctionQ41103346
Induction of brain cytochrome P-450IIE1 by chronic ethanol treatmentQ42509884
A psychopharmacological study of the relationship between brain catalase activity and ethanol-induced locomotor activity in miceQ42631118
Incorporation of label from [1-14C]ethanol into the glutamate–glutamine pools of rat brain in vivoQ42924618
Relationship of brain ethanol metabolism to the hypnotic effect of ethanol. I: Studies in outbred animalsQ43707044
Relationship of brain ethanol metabolism to the hypnotic effect of ethanol. II: Studies in selectively bred rats and miceQ43707047
The reinforcing effects of acetaldehyde in the posterior ventral tegmental area of alcohol-preferring ratsQ43921558
Ethanol effects on local cerebral glucose utilization in high-alcohol-drinking and low-alcohol-drinking ratsQ44376229
Acetaldehyde increases dopaminergic neuronal activity in the VTA.Q44770261
Acute effects of ethanol on regional brain glucose metabolism and transportQ45004127
Acetaldehyde sequestering prevents ethanol-induced stimulation of mesolimbic dopamine transmission.Q46205904
Low doses of alcohol substantially decrease glucose metabolism in the human brainQ46639065
Is ethanol a pro-drug? Acetaldehyde contribution to brain ethanol effects.Q46697624
Magnesium deficiency enhances hydrogen peroxide production and oxidative damage in chick embryo hepatocyte in vitroQ46963904
Preferential utilization of acetate by astrocytes is attributable to transport.Q47892655
Ethanol oxidation in the living brainQ48092243
Ethanol and acetaldehyde levels in cerebrospinal fluid during ethanol oxidation in the rat.Q48146982
P433issue35
P407language of work or nameEnglishQ1860
P304page(s)14444-14449
P577publication date2013-08-12
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleOxidation of ethanol in the rat brain and effects associated with chronic ethanol exposure
P478volume110