E22Q-mutant Abeta peptide (AbetaDutch) increases vascular but reduces parenchymal Abeta deposition

scientific article published on 13 February 2009

E22Q-mutant Abeta peptide (AbetaDutch) increases vascular but reduces parenchymal Abeta deposition is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2353/AJPATH.2009.080790
P932PMC publication ID2665734
P698PubMed publication ID19218342
P5875ResearchGate publication ID24011591

P50authorMathias JuckerQ29918595
Matthias StaufenbielQ83938392
P2093author name stringMartin C Herzig
Yvonne S Eisele
P2860cites workCystatin C modulates cerebral beta-amyloidosisQ24300978
Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40.Q33245678
Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengthsQ34018579
Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.Q34341174
Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleusQ36082193
Neurovascular mechanisms of Alzheimer's neurodegenerationQ36088588
The cerebral beta-amyloid angiopathies: hereditary and sporadicQ36448518
Mechanism of cerebral beta-amyloid angiopathy: murine and cellular modelsQ36448521
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathologyQ36724967
Hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D): I--A review of clinical, radiologic and genetic aspectsQ36810961
Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease.Q37118134
Specific Compositions of Amyloid-β Peptides as the Determinant of Toxic β-AggregationQ40652018
The role of A beta 42 in Alzheimer's diseaseQ42463004
Cerebral vascular accumulation of Dutch-type Abeta42, but not wild-type Abeta42, in hereditary cerebral hemorrhage with amyloidosis, Dutch typeQ48106759
BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic miceQ48123992
Abeta40 inhibits amyloid deposition in vivo.Q48305645
Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-proteinQ48407932
Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy.Q48974670
Expression of a normal and variant Alzheimer's beta-protein gene in amyloid of hereditary cerebral hemorrhage, Dutch type: DNA and protein diagnostic assays.Q53185035
Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells.Q53235221
Pathologic amyloid beta-protein cell surface fibril assembly on cultured human cerebrovascular smooth muscle cellsQ64360858
Abeta40 protects non-toxic Abeta42 monomer from aggregationQ80270099
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)722-726
P577publication date2009-02-13
P1433published inThe American Journal of PathologyQ4744259
P1476titleE22Q-mutant Abeta peptide (AbetaDutch) increases vascular but reduces parenchymal Abeta deposition
P478volume174

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cites work (P2860)
Q33759956APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis
Q44464053Comparative fibril formation of analogs corresponding to the (12-24) segment of the β-amyloid peptide
Q33793048Early-onset formation of parenchymal plaque amyloid abrogates cerebral microvascular amyloid accumulation in transgenic mice
Q38198632Imaging of cerebrovascular pathology in animal models of Alzheimer's disease
Q38001784Molecular consequences of amyloid precursor protein and presenilin mutations causing autosomal-dominant Alzheimer's disease
Q34838288Observations in APP bitransgenic mice suggest that diffuse and compact plaques form via independent processes in Alzheimer's disease
Q49832870Rodent Models of Cerebral Microinfarct and Microhemorrhage.
Q42921084Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice
Q47222878Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease

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