TPH gene polymorphisms are associated with disease perception and quality of life in women with irritable bowel syndrome

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TPH gene polymorphisms are associated with disease perception and quality of life in women with irritable bowel syndrome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/1099800412466694
P932PMC publication ID3766405
P698PubMed publication ID23172723
P5875ResearchGate publication ID233745970

P2093author name stringKevin C Cain
Margaret M Heitkemper
Monica E Jarrett
Ruth Kohen
Sang-Eun Jun
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A regulatory variant of the human tryptophan hydroxylase-2 gene biases amygdala reactivityQ34437037
Amygdala responsiveness is modulated by tryptophan hydroxylase-2 gene variation.Q34462273
Acute tryptophan depletion affects brain-gut responses in irritable bowel syndrome patients and controls.Q34552619
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Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndromeQ34673928
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LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotoninQ34790812
Increased risk of suicide attempt in mood disorders and TPH1 genotypeQ35633770
Developmental role of tryptophan hydroxylase in the nervous systemQ36829277
The tryptophan hydroxylase inhibitor LX1031 shows clinical benefit in patients with nonconstipating irritable bowel syndromeQ36998938
Five personality dimensions in patients with irritable bowel syndromeQ37062585
Acute tryptophan depletion alters the effective connectivity of emotional arousal circuitry during visceral stimuli in healthy women.Q37412200
Tryptophan hydroxylase-2 (TPH2) in disorders of cognitive control and emotion regulation: a perspective.Q37831691
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Targeting the 5-HT(3) receptor in the treatment of irritable bowel syndromeQ37852453
Identification and analysis of new sequence variants in the human tryptophan hydroxylase (TpH) geneQ40778403
The psychometric properties of the Composite International Diagnostic InterviewQ41721583
Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin productionQ42870234
Genetic TPH2 variants and the susceptibility for migraine: association of a TPH2 haplotype with migraine without auraQ42925490
Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteersQ43004376
Suicide attempts and the tryptophan hydroxylase geneQ43590743
Association of anger-related traits with SNPs in the TPH gene.Q44194159
Association between the TPH gene A218C polymorphism and suicidal behavior: a meta-analysisQ44697632
Regional mRNA expression of a second tryptophan hydroxylase isoform in postmortem tissue samples of two human brainsQ44910808
Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burdenQ44985819
Support for the involvement of TPH2 gene in affective disordersQ44985822
Different associations of health related quality of life with pain, psychological distress and coping strategies in patients with irritable bowel syndrome and inflammatory bowel disorderQ45818716
The tryptophan hydroxylase gene influences risk for bipolar disorder but not major depressive disorder: results of meta-analysesQ46229370
Haplotype analysis reveals tryptophan hydroxylase (TPH) 1 gene variants associated with major depressionQ46705358
Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populationsQ46735169
Relationship of SERT polymorphisms to depressive and anxiety symptoms in irritable bowel syndromeQ46972024
Tryptophan hydroxylase 1 gene (TPH1) moderates the influence of social support on depressive symptoms in adultsQ48353366
Association between a polymorphism in the promoter region of the TPH2 gene and the personality trait of harm avoidanceQ48420456
Association between the TPH1 A218C polymorphism and risk of mood disorders and alcohol dependence: evidence from the current studiesQ48866718
The development of a cognitive scale for functional bowel disorders.Q51991894
Evaluation of a new quality of life questionnaire for patients with irritable bowel syndromeQ52000930
Psychosocial Aspects of the Functional Gastrointestinal DisordersQ60701387
Genetic Risk Factors for Post-Infectious Irritable Bowel Syndrome Following a Waterborne Outbreak of GastroenteritisQ61536312
Familial association in adults with functional gastrointestinal disordersQ74335901
The relationship between psychological distress and gastrointestinal symptoms in women with irritable bowel syndromeQ74607996
Natural killer cell function and psychological distress in women with and without irritable bowel syndromeQ78325320
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectirritable bowel syndromeQ838966
quality of lifeQ13100823
P304page(s)95-104
P577publication date2012-11-20
P1433published inBiological Research for NursingQ4914964
P1476titleTPH gene polymorphisms are associated with disease perception and quality of life in women with irritable bowel syndrome
P478volume16

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cites work (P2860)
Q92582085A theoretical framework for interaction of nursing discipline with genetics and genomics
Q47660714Association between single nucleotide polymorphisms of TPH1 and TPH2 genes, and depressive disorders
Q28654636Biological pathways, candidate genes, and molecular markers associated with quality-of-life domains: an update
Q26775107Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis.
Q38685668Lessons learned--resolving the enigma of genetic factors in IBS.
Q40800045Polymorphisms of the TRPV2 and TRPV3 genes associated with fibromyalgia in a Korean population
Q41688642Serotonin-Related Gene Variants in Patients with Irritable Bowel Syndrome and Depressive or Anxiety Disorders
Q55080500The TPH1 rs211105 gene polymorphism affects abdominal symptoms and quality of life of diarrhea-predominant irritable bowel syndrome.

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