Extracellular matrix and pathogenic mechanisms in osteoarthritis

scientific article published on January 2008

Extracellular matrix and pathogenic mechanisms in osteoarthritis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1007/S11926-008-0006-9
P698PubMed publication ID18457609

P50authorTimothy E. HardinghamQ42157777
P2860cites workMatrilin-3 mutations that cause chondrodysplasias interfere with protein trafficking while a mutation associated with hand osteoarthritis does notQ24674454
Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173]Q24816771
A glycine to aspartic acid substitution of COL2A1 in a family with the Strudwick variant of spondyloepimetaphyseal dysplasiaQ28202373
Osteoarthritis: new insights. Part 1: the disease and its risk factors.Q33921631
COMP mutations, chondrocyte function and cartilage matrixQ34391274
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitroQ34407615
Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5.Q34607880
Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repairQ35785741
Classification of osteoarthritis biomarkers: a proposed approach.Q36491949
Animal models of osteoarthritis: lessons learned while seeking the "Holy Grail".Q36560186
Proteoglycans: many forms and many functionsQ36777685
The futility of current approaches to chondroprotectionQ36806523
Biological markers in osteoarthritisQ36835538
Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthriQ39344079
The structure and function of cartilage proteoglycansQ39652700
A mutation in the variable repeat region of the aggrecan gene (AGC1) causes a form of spondyloepiphyseal dysplasia associated with severe, premature osteoarthritisQ41859694
A new autosomal recessive form of Stickler syndrome is caused by a mutation in the COL9A1 geneQ42035441
Yet more evidence that osteoarthritis is not a cartilage diseaseQ42955504
Research in osteoarthritisQ44008737
Raised chondroitin sulfate epitopes and hyaluronan in serum from rheumatoid arthritis and osteoarthritis patientsQ46821927
Retroviral transduction with SOX9 enhances re-expression of the chondrocyte phenotype in passaged osteoarthritic human articular chondrocytes.Q50486810
Differences in biomarkers of type II collagen in atrophic and hypertrophic osteoarthritis of the hip: implications for the differing pathobiologies.Q53592357
The role of sequence variations within the genes encoding collagen II, IX and XI in non-syndromic, early-onset osteoarthritis.Q54661763
Type X collagen synthesis in human osteoarthritic cartilage. Indication of chondrocyte hypertrophyQ68191446
Immunolocalization of type X collagen in normal fetal and adult osteoarthritic cartilage with monoclonal antibodiesQ71727159
New developments in the search for genetic determinants of osteoarthritisQ79409916
Can treatment with risedronate benefit patients with knee osteoarthritis?Q79888355
Bone, not cartilage, should be the major focus in osteoarthritisQ80406971
Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis--structure, chaos and senescenceQ80543447
Retention of the matricellular protein SPARC in the endoplasmic reticulum of chondrocytes from patients with pseudoachondroplasiaQ81477500
Assessment of the utility of biomarkers of osteoarthritis in the guinea pigQ83296983
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectosteoarthritisQ62736
extracellular matrixQ193825
P304page(s)30-36
P577publication date2008-01-01
P1433published inCurrent Rheumatology ReportsQ23930052
P1476titleExtracellular matrix and pathogenic mechanisms in osteoarthritis
P478volume10

Reverse relations

cites work (P2860)
Q34067264Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis.
Q37353085Advanced osteoarthritis in humans is associated with altered collagen VI expression and upregulation of ER-stress markers Grp78 and bag-1.
Q34158408Age dependent changes in cartilage matrix, subchondral bone mass, and estradiol levels in blood serum, in naturally occurring osteoarthritis in Guinea pigs
Q28752317Comparative genomic analysis of the zebra finch degradome provides new insights into evolution of proteases in birds and mammals
Q39540092Computational Insights into ADAMTS4, ADAMTS5 and MMP13 Inhibitor Selectivity
Q91733642Decellularized ECM-derived bioinks: Prospects for the future
Q43105023Design, synthesis, and preliminary biological evaluation of pyrrolo[3,4-c]quinolin-1-one and oxoisoindoline derivatives as aggrecanase inhibitors.
Q47130760Effect of Acupotomy on FAK-PI3K Signaling Pathways in KOA Rabbit Articular Cartilages
Q39867495Extracellular matrix, leukocyte migration and laminitis
Q48543654Fell-Muir lecture: cartilage 2010 - the known unknowns
Q34824573Glucan HBP-A increase type II collagen expression of chondrocytes in vitro and tissue engineered cartilage in vivo
Q38362244Glucosamine Hydrochloride but Not Chondroitin Sulfate Prevents Cartilage Degradation and Inflammation Induced by Interleukin-1α in Bovine Cartilage Explants
Q45251665Identification of long noncoding RNA associated with osteoarthritis in humans.
Q37310621Immunomodulatory and anti-inflammatory effects of chondroitin sulphate
Q35258198Inhibition of interleukin-1beta-stimulated dedifferentiation of chondrocytes via controlled release of CrmA from hyaluronic acid-chitosan microspheres
Q38710166Knee Osteoarthritis and Risk of Hypertension: A longitudinal cohort study
Q40817365MicroRNA-140 and the silencing of osteoarthritis
Q51767015Osteoarthristis Increases the Risk of Cardiovascular Disease: Data from the Osteoarthritis Initiative.
Q35846445T1ρ magnetic resonance imaging quantification of early articular cartilage degeneration in a rabbit model
Q37715519The effect of lipoaspirates vs. dissected abdominal fat on breast cancer cells in vitro
Q53065354[Histopathological degeneration score of fibrous cartilage. Low- and high-grade meniscal degeneration].
Q83176792[Meniscal degeneration score and NITEGE expression : immunohistochemical detection of NITEGE in advanced meniscal degeneration]

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