Na+ transport in cardiac myocytes; Implications for excitation-contraction coupling.

scientific article published on March 2009

Na+ transport in cardiac myocytes; Implications for excitation-contraction coupling. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/IUB.163
P932PMC publication ID2669704
P698PubMed publication ID19243007
P5875ResearchGate publication ID24040309

P50authorDonald M. BersQ40664240
P2093author name stringSanda Despa
P2860cites workCrystal structure of the sodium–potassium pumpQ22337247
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac deathQ24294267
Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathwayQ24305894
Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-BQ24337311
The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysisQ27648908
A single Na(+) channel mutation causing both long-QT and Brugada syndromesQ28139738
The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expressionQ28144199
Ischemia-induced phosphorylation of phospholemman directly activates rat cardiac Na/K-ATPaseQ28181728
Novel, ultraslow inactivating sodium current in human ventricular cardiomyocytesQ28290775
The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heartQ28512885
The Na+/K+-ATPase alpha2-isoform regulates cardiac contractility in rat cardiomyocytesQ28570289
Distribution of proteins implicated in excitation-contraction coupling in rat ventricular myocytesQ28581347
Identification of a specific role for the Na,K-ATPase alpha 2 isoform as a regulator of calcium in the heartQ28589440
Phospholemman-mediated activation of Na/K-ATPase limits [Na]i and inotropic state during beta-adrenergic stimulation in mouse ventricular myocytesQ30436468
Unitary anion currents through phospholemman channel moleculesQ30463696
Helix packing of functionally important regions of the cardiac Na(+)-Ca(2+) exchangerQ31465471
Clinical and genetic heterogeneity of right bundle branch block and ST-segment elevation syndrome: A prospective evaluation of 52 familiesQ33145879
Purification and complete sequence determination of the major plasma membrane substrate for cAMP-dependent protein kinase and protein kinase C in myocardiumQ33263494
Phospholemman (FXYD1) associates with Na,K-ATPase and regulates its transport propertiesQ34038902
Na-Ca exchange and the trigger for sarcoplasmic reticulum Ca release: studies in adult rabbit ventricular myocytesQ34168427
Na/Ca exchange and Na/K-ATPase function are equally concentrated in transverse tubules of rat ventricular myocytesQ34183706
Effect of strophanthidin on intracellular Na ion activity and twitch tension of constantly driven canine cardiac Purkinje fibersQ34255862
Intracellular Na+ regulation in cardiac myocytes.Q35090052
Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channelsQ35157593
Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytesQ35679654
Localization of sodium channels in intercalated disks modulates cardiac conductionQ35836821
Na+ pump low and high ouabain affinity alpha subunit isoforms are differently distributed in cellsQ36022585
The role of Na(+)-Ca2+ exchange in activation of excitation-contraction coupling in rat ventricular myocytesQ71471038
Alteration of Na,K-ATPase subunit mRNA and protein levels in hypertrophied rat heartQ72725028
Reduced myocardial Na+, K(+)-pump capacity in congestive heart failure following myocardial infarction in ratsQ77117753
Functional analysis of Na+/K+-ATPase isoform distribution in rat ventricular myocytesQ80057919
Density and sub-cellular distribution of cardiac and neuronal sodium channel isoforms in rat ventricular myocytesQ80099104
Expression and phosphorylation of the na-pump regulatory subunit phospholemman in heart failureQ81059387
Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins.Q36082294
Molecular physiology of cardiac repolarizationQ36267771
Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.Q36412283
Allosteric activation of sodium-calcium exchange activity by calcium: persistence at low calcium concentrationsQ36436640
Cardiac ankyrins: Essential components for development and maintenance of excitable membrane domains in heartQ36464922
Distribution of the Na(+)-Ca2+ exchange protein in mammalian cardiac myocytes: an immunofluorescence and immunocolloidal gold-labeling studyQ36531271
The promiscuous nature of the cardiac sodium currentQ36731634
Na:Ca stoichiometry and cytosolic Ca-dependent activation of NCX in intact cardiomyocytesQ36736953
What we know about the structure of NCX1 and how it relates to its functionQ36736977
Identification of the high affinity Ca(2+)-binding domain of the cardiac Na(+)-Ca2+ exchangerQ38304444
Phosphorylation-dependent conformational switch in spin-labeled phospholamban bound to SERCA.Q39353068
Dual control of cardiac Na+ Ca2+ exchange by PIP(2): electrophysiological analysis of direct and indirect mechanismsQ40125661
Phospholemman phosphorylation alters its fluorescence resonance energy transfer with the Na/K-ATPase pumpQ40237867
Helix packing of the cardiac Na+-Ca2+ exchanger: proximity of transmembrane segments 1, 2, and 6.Q40265655
Increased Na+/H+-exchange activity is the cause of increased [Na+]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure modelQ40598960
Predicted location and limited accessibility of protein kinase A phosphorylation site on Na-K-ATPaseQ40720018
Distribution, surface density, and membrane area of diadic junctional contacts between plasma membrane and terminal cisterns in mammalian ventricleQ41046915
Interaction of PIP(2) with the XIP region of the cardiac Na/Ca exchangerQ41728594
Activity of cAMP-dependent protein kinase and Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human heartsQ42475810
Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardiumQ42524047
Regulation of the cardiac Na(+)-Ca2+ exchanger by Ca2+. Mutational analysis of the Ca(2+)-binding domainQ42976963
Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchangedQ44009242
A new topological model of the cardiac sarcolemmal Na+-Ca2+ exchangerQ44079042
Na+-Ca2+ exchange activity is localized in the T-tubules of rat ventricular myocytesQ44112807
Postnatal changes in Na,K-ATPase isoform expression in rat cardiac ventricle. Conservation of biphasic ouabain affinityQ44284534
The alpha2 isoform of Na,K-ATPase mediates ouabain-induced cardiac inotropy in miceQ44618310
Serine 68 phosphorylation of phospholemman: acute isoform-specific activation of cardiac Na/K ATPaseQ45203231
Increased late sodium current in myocytes from a canine heart failure model and from failing human heart.Q45284438
Subcellular distribution of sodium pump isoform subunits in mammalian cardiac myocytes.Q45945297
Immunologic identification of Na+,K(+)-ATPase isoforms in myocardium. Isoform change in deoxycorticosterone acetate-salt hypertensionQ46243995
Low efficiency of Ca2+ entry through the Na(+)-Ca2+ exchanger as trigger for Ca2+ release from the sarcoplasmic reticulum. A comparison between L-type Ca2+ current and reverse-mode Na(+)-Ca2+ exchangeQ46368147
Isoproterenol-induced phosphorylation of a 15-kilodalton sarcolemmal protein in intact myocardiumQ46407758
Relative abundance of alpha2 Na(+) pump isoform influences Na(+)-Ca(2+) exchanger currents and Ca(2+) transients in mouse ventricular myocytesQ46502215
Phospholemman-phosphorylation mediates the beta-adrenergic effects on Na/K pump function in cardiac myocytesQ46588903
A persistent sodium current in rat ventricular myocytesQ46623765
Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts--role of late sodium current and intracellular ion accumulationQ46624550
An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytesQ46725746
Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failureQ46790561
Phosphorylation of phospholemman (FXYD1) by protein kinases A and C modulates distinct Na,K-ATPase isozymesQ48773026
Repolarization abnormalities in cardiomyocytes of dogs with chronic heart failure: role of sustained inward current.Q51461497
Differential distribution and regulation of mouse cardiac Na+/K+-ATPase alpha1 and alpha2 subunits in T-tubule and surface sarcolemmal membranes.Q54361992
Ankyrin binding to (Na+ + K+)ATPase and implications for the organization of membrane domains in polarized cellsQ57253842
Structural parts involved in activation and inactivation of the sodium channelQ59072056
P433issue3
P304page(s)215-221
P577publication date2009-03-01
P1433published inIUBMB LifeQ15764029
P1476titleNa+ transport in cardiac myocytes; Implications for excitation-contraction coupling
P478volume61

Reverse relations

cites work (P2860)
Q36096065A common variant in SLC8A1 is associated with the duration of the electrocardiographic QT interval
Q36041897Ablation of sarcolipin results in atrial remodeling
Q33820434Cardiac Ion Channel Regulation in Obesity and the Metabolic Syndrome: Relevance to Long QT Syndrome and Atrial Fibrillation
Q60919560Cardiolipotoxicity, Inflammation, and Arrhythmias: Role for Interleukin-6 Molecular Mechanisms
Q36029885Enzyme localization, crowding, and buffers collectively modulate diffusion-influenced signal transduction: Insights from continuum diffusion modeling
Q27022674Hyperkalemic cardioplegia for adult and pediatric surgery: end of an era?
Q59125620Hypokalemia-Induced Arrhythmias and Heart Failure: New Insights and Implications for Therapy
Q57221888Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians
Q37680390Increased myofilament Ca2+-sensitivity and arrhythmia susceptibility.
Q35145345Inhibiting Na+/K+ ATPase can impair mitochondrial energetics and induce abnormal Ca2+ cycling and automaticity in guinea pig cardiomyocytes
Q37783810Mechanisms of protein kinase A anchoring
Q30525513Modeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometries
Q36483480Na⁺/K⁺-ATPase E960 and phospholemman F28 are critical for their functional interaction
Q39708587Stabilization of the α2 isoform of Na,K-ATPase by mutations in a phospholipid binding pocket
Q37082130While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKIIδ-KO mice

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