c-Met targeted therapy of cholangiocarcinoma

scientific article published on May 2008

c-Met targeted therapy of cholangiocarcinoma is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3748/WJG.14.2990
P932PMC publication ID2712164
P698PubMed publication ID18494048

P2093author name stringGianfranco Alpini
Frank Mott
Arthur-E Frankel
Matei-P Socoteanu
P2860cites workHGF/SF-Met signaling in tumor progressionQ36027374
The role of chemotherapy in cholangiocarcinomaQ36164434
Toxin conjugate therapy of cancerQ36336389
A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenograftsQ40144642
Involvement of c-Met/hepatocyte growth factor pathway in cholangiocarcinoma cell invasion and its therapeutic inhibition with small interfering RNA specific for c-MetQ40236740
Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenograftsQ40314133
Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cellsQ40497486
Bile acids activate EGF receptor via a TGF-alpha-dependent mechanism in human cholangiocyte cell linesQ40668106
Is liver transplantation indicated for cholangiocarcinoma?Q40797119
Outcomes analysis for 280 patients with cholangiocarcinoma treated with liver transplantation over an 18-year periodQ42635593
Overexpression of C-NEU and C-MET during rat liver cholangiocarcinogenesis: A link between biliary intestinal metaplasia and mucin-producing cholangiocarcinomaQ44860005
A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycinQ46402569
Epidermal growth factor receptor immunoreactivity in gallbladder and extrahepatic biliary tract tumoursQ50163916
c-erbB-2 and c-Met expression relates to cholangiocarcinogenesis and progression of intrahepatic cholangiocarcinoma.Q52122642
Serum Proteomic Classifier for Predicting Response to Epidermal Growth Factor Receptor Inhibitor Therapy: Have We Built a Better Mousetrap?Q57272627
Chronic Bile Duct Injury Associated with Fibrotic Matrix Microenvironment Provokes Cholangiocarcinoma in p53-Deficient MiceQ58214837
Clinical significance of hepatocyte growth factor and c-Met expression in extrahepatic biliary tract cancersQ78056476
Pharmacokinetics and safety of a fully human hepatocyte growth factor antibody, AMG 102, in cynomolgus monkeysQ80371652
Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752Q24541450
Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal modelsQ24629814
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of CanadaQ27860904
Met receptor tyrosine kinase: enhanced signaling through adapter proteinsQ28140219
A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivoQ28183526
Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasionQ28184585
HGF/SF-met signaling in the control of branching morphogenesis and invasionQ28202466
Met, metastasis, motility and moreQ28235183
Targeting the c-Met signaling pathway in cancerQ28246393
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivoQ28270305
Targeting the tumor and its microenvironment by a dual-function decoy Met receptorQ28272715
Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumorsQ28295039
Erlotinib in previously treated non-small-cell lung cancerQ29547546
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials GroupQ29619344
Gemcitabine, 5-fluorouracil, and leucovorin in advanced biliary tract and gallbladder carcinoma: a North Central Cancer Treatment Group phase II trialQ33363800
Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapyQ33984809
Phase II study of erlotinib in patients with advanced biliary cancerQ33997258
A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinaseQ34263863
Treatment of hilar cholangiocarcinoma (Klatskin tumors) with hepatic resection or transplantationQ34346870
Liver transplantation for cholangiocellular carcinoma: analysis of a single-center experience and review of the literatureQ34468865
Erlotinib in lung cancer - molecular and clinical predictors of outcomeQ34559274
Immunohistochemical demonstration of MET overexpression in human intrahepatic cholangiocarcinoma and in hepatolithiasisQ34745711
Cellular and molecular biology of biliary tract cancersQ35073918
A review and update on cholangiocarcinomaQ35817693
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectcholangiocarcinomaQ124292
P304page(s)2990-2994
P577publication date2008-05-01
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titlec-Met targeted therapy of cholangiocarcinoma
P478volume14

Reverse relations

cites work (P2860)
Q26784091An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma
Q38597008Cholangiocarcinoma: from molecular biology to treatment
Q35919809Hypoxia enhances cholangiocarcinoma invasion through activation of hepatocyte growth factor receptor and the extracellular signal‑regulated kinase signaling pathway
Q41231601Is c-Met oncoprotein expression an adverse prognosticator in extrahepatic bile duct cancer treated with curative resection followed by adjuvant chemoradiotherapy?
Q39033749Molecular Markers in the Pathogenesis of Cholangiocarcinoma: Potential for Early Detection and Selection of Appropriate Treatment
Q64085995Molecular Pathogenesis of Cholangiocarcinoma
Q37878879Molecular mechanisms of cholangiocarcinoma
Q34391135New insights on cholangiocarcinoma.
Q55017802PF-2341066 combined with celecoxib promotes apoptosis and inhibits proliferation in human cholangiocarcinoma QBC939 cells.
Q41073453Prognostic Value of C-met Expression in Cholangiocarcinoma
Q35108386Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma
Q42700697Prognostic value of c-Met overexpression in pancreatic adenocarcinoma: a meta-analysis
Q54490877Proteinase-activated receptor 2 (PAR(2)) in cholangiocarcinoma (CCA) cells: effects on signaling and cellular level.
Q41077332The Clinical Impact of c-MET Over-Expression in Advanced Biliary Tract Cancer (BTC).
Q36683019The challenge of cholangiocarcinoma: dissecting the molecular mechanisms of an insidious cancer
Q26865749The significance of genetics for cholangiocarcinoma development
Q90113516Therapeutic Potential of Autophagy Modulation in Cholangiocarcinoma

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