Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent

scientific article published on 04 February 2009

Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YDBIO.2009.01.036
P932PMC publication ID2674121
P698PubMed publication ID19389352
P5875ResearchGate publication ID24354846

P50authorJames K. ChenQ39883191
P2093author name stringJohn K Mich
Deborah Yelon
Erez Raz
Ari J Firestone
Heiko Blaser
Natalie A Thomas
P2860cites workp53 activation by knockdown technologiesQ21563456
A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitroQ24315704
Small molecule modulation of Smoothened activityQ24540343
Isolation of a DEAD-family protein gene that encodes a murine homolog of Drosophila vasa and its specific expression in germ cell lineageQ24564486
A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewalQ24595550
Bmp4 is required for the generation of primordial germ cells in the mouse embryoQ24608134
Inhibition of Hedgehog signaling by direct binding of cyclopamine to SmoothenedQ24682703
Stages of embryonic development of the zebrafishQ27860947
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamineQ28138510
Requirement of Bmp8b for the generation of primordial germ cells in the mouseQ28140750
Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouseQ28201223
Hedgehog signaling in animal development: paradigms and principlesQ28208463
Two-color whole-mount in situ hybridization to vertebrate and Drosophila embryosQ28239551
Control of chemokine-guided cell migration by ligand sequestrationQ28268329
Divergence of hedgehog signal transduction mechanism between Drosophila and mammalsQ28295678
Mutations in half baked/E-cadherin block cell behaviors that are necessary for teleost epibolyQ28305628
Mili, a mammalian member of piwi family gene, is essential for spermatogenesisQ28585613
The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumoursQ28586692
Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatchedQ28589361
miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesisQ28589737
Conserved role of nanos proteins in germ cell developmentQ28590495
Control over the morphology and segregation of Zebrafish germ cell granules during embryonic developmentQ30482494
Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migrationQ33398523
Zebrafish immunohistochemistryQ33741786
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish.Q34003437
Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation.Q34298296
Production of maternal-zygotic mutant zebrafish by germ-line replacementQ34380381
Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potentialQ34421441
HMG-CoA reductase guides migrating primordial germ cellsQ34483587
A zebrafish nanos-related gene is essential for the development of primordial germ cellsQ35082150
Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterningQ35189275
Primordial germ-cell development: the zebrafish perspectiveQ35209968
toutvelu, a regulator of heparan sulfate proteoglycan biosynthesis, controls guidance cues for germ-cell migrationQ35846373
DE-Cadherin is required for intercellular motility during Drosophila oogenesisQ36255738
In vivo migration: a germ cell perspective.Q36506792
Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo).Q37633966
Transition from non-motile behaviour to directed migration during early PGC development in zebrafishQ38321612
dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival.Q38351230
Zebrafish vasa homologue RNA is localized to the cleavage planes of 2- and 4-cell-stage embryos and is expressed in the primordial germ cells.Q38556529
Soma-germ line competition for lipid phosphate uptake regulates germ cell migration and survival.Q40521784
A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptorQ40612740
Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate developmentQ40666046
Identification of tissues and patterning events required for distinct steps in early migration of zebrafish primordial germ cells.Q40790477
Zebrafish vasa RNA but not its protein is a component of the germ plasm and segregates asymmetrically before germline specification.Q42131238
Hedgehog does not guide migrating Drosophila germ cellsQ43115430
Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity.Q43700227
Neural crest emigration from the neural tube depends on regulated cadherin expressionQ44364647
Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryoQ44515860
Isoprenoids control germ cell migration downstream of HMGCoA reductaseQ44762411
Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryoQ44863919
E-cadherin regulates cell movements and tissue formation in early zebrafish embryosQ44910203
Primordial germ cell migration and the assembly of the Drosophila embryonic gonad.Q46001162
E-cadherin is required for gastrulation cell movements in zebrafishQ46499462
A protein component of Drosophila polar granules is encoded by vasa and has extensive sequence similarity to ATP-dependent helicasesQ46631755
HMGCoA reductase potentiates hedgehog signaling in Drosophila melanogasterQ46780215
Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish.Q47073417
Autonomous modes of behavior in primordial germ cell migrationQ47073427
Zebrafish smoothened functions in ventral neural tube specification and axon tract formationQ47073486
Guidance of primordial germ cell migration by the chemokine SDF-1.Q47073968
Signaling pathways controlling primordial germ cell migration in zebrafishQ47073985
A vasa-like gene in zebrafish identifies putative primordial germ cellsQ48046238
Nanos is the localized posterior determinant in DrosophilaQ48214468
Hedgehog signaling in germ cell migration.Q52129206
Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in Drosophila.Q52458614
Expression and function of clift in the development of somatic gonadal precursors within the Drosophila mesoderm.Q52552496
Migration of zebrafish primordial germ cells: a role for myosin contraction and cytoplasmic flow.Q53012779
Requirement ofBmp8bfor the Generation of Primordial Germ Cells in the MouseQ55884159
Whole-mount in situ hybridizations on zebrafish embryos using a mixture of digoxigenin- and fluorescein-labelled probesQ72409853
Regulation of E- and P-cadherin expression correlated with melanocyte migration and diversificationQ73141854
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcell migrationQ189092
Danio rerioQ169444
P304page(s)342-354
P577publication date2009-02-04
P1433published inDevelopmental BiologyQ3025402
P1476titleGerm cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent
P478volume328