In vivo evidence of increased nNOS activity in acute MPTP neurotoxicity: a functional pharmacological MRI study

scientific article published on 31 August 2013

In vivo evidence of increased nNOS activity in acute MPTP neurotoxicity: a functional pharmacological MRI study is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2013/964034
P932PMC publication ID3773403
P698PubMed publication ID24069609
P5875ResearchGate publication ID257076002

P2093author name stringChen Chang
Chiao-Chi V Chen
Tiing Yee Siow
Kai-Ping N Chow
Nina Wan
P2860cites workCyclic guanosine monophosphate as a mediator of vasodilationQ24623087
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Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson's diseaseQ35018093
Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).Q36503887
Quantification of relative cerebral blood flow change by flow-sensitive alternating inversion recovery (FAIR) technique: application to functional mappingQ36672899
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Nitric oxide--the endothelium-derived relaxing factor and its role in endothelial functionsQ37820807
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MPTP, MPP+ and mitochondrial functionQ41382377
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.Q41664189
Proton magnetic resonance spectroscopy in Parkinson's disease and progressive supranuclear palsyQ41847841
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In vitro and in vivo evidences that antioxidant action contributes to the neuroprotective effects of the neuronal nitric oxide synthase and monoamine oxidase-B inhibitor, 7-nitroindazoleQ42523167
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The mechanisms of neuronal death produced by mitochondrial toxin 3-nitropropionic acid: the roles of N-methyl-D-aspartate glutamate receptors and mitochondrial calcium overload.Q44035217
The neuronal nitric oxide synthase inhibitor 7-nitroindazole also inhibits the monoamine oxidase-B-catalyzed oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridineQ45104121
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brainQ45256207
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Regional CBF changes in Parkinson's disease: a correlation with motor dysfunctionQ48201439
The effects of levodopa use on diffusion coefficients in various brain regions in Parkinson's diseaseQ48265517
Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.Q48310314
What is the correct value for the brain--blood partition coefficient for water?Q48516478
Proton magnetic resonance spectroscopy in Parkinson's disease and atypical parkinsonian disordersQ48586206
Uptake of MPP(+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP.Q48601969
Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphoraseQ48650129
Nitric oxide synthase inhibition and MPTP-induced toxicity in the common marmosetQ48679768
MPP(+)-induced neurotoxicity in mouse is age-dependent: evidenced by the selective inhibition of complexes of electron transportQ49011944
Threshold effects and control of oxidative phosphorylation in nonsynaptic rat brain mitochondriaQ49043208
Pharmacological magnetic resonance imaging: a new application for functional MRI.Q51389065
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Inhibition of nitric oxide synthesis impairs autoregulation of local cerebral blood flow in the rat.Q54245680
Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson diseaseQ56567926
Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brainQ59062956
Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+Q69876986
Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic studyQ70192548
Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivoQ71038834
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole: effects upon local cerebral blood flow and glucose use in the ratQ71710210
Half-life of nitric oxide in aqueous solutions with and without haemoglobinQ71856450
Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamineQ72059888
Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicityQ72332264
Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivoQ73760293
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
neurotoxicityQ3338704
toxic encephalopathyQ7830379
P304page(s)964034
P577publication date2013-08-31
P1433published inBioMed Research InternationalQ17509958
P1476titleIn vivo evidence of increased nNOS activity in acute MPTP neurotoxicity: a functional pharmacological MRI study
P478volume2013

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cites work (P2860)
Q45305568Aberrant astrocytes impair vascular reactivity in Huntington disease
Q43679571Neurotoxin mechanisms and processes relevant to Parkinson's disease: an update

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