TNF: a master switch for inflammation to cancer

scientific article published on May 2008

TNF: a master switch for inflammation to cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.2741/3066
P698PubMed publication ID18508572
P5875ResearchGate publication ID5341543

P50authorGautam SethiQ50077635
P2093author name stringBharat B Aggarwal
Bokyung Sung
P2860cites workHypoestoxide, a novel anti-inflammatory natural diterpene, inhibits the activity of IkappaB kinaseQ39319116
P921main subjectinflammationQ101991
TNFQ18032037
P304page(s)5094-5107
P577publication date2008-05-01
P1433published inFrontiers in BioscienceQ5506062
P1476titleTNF: a master switch for inflammation to cancer
P478volume13

Reverse relations

cites work (P2860)
Q905253095-Aminosalicylic acid downregulates the growth and virulence of Escherichia coli associated with IBD and colorectal cancer, and upregulates host anti-inflammatory activity
Q51047559A novel 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNFα by abrogating NF-κB activation cascade.
Q39634814A novel role for TNFAIP2: its correlation with invasion and metastasis in nasopharyngeal carcinoma.
Q39281011ADAM-17: a novel therapeutic target for triple negative breast cancer
Q42329928Ac-SDKP suppresses TNF-α-induced ICAM-1 expression in endothelial cells via inhibition of IκB kinase and NF-κB activation
Q37179468Acceleration of cutaneous wound healing by brassinosteroids.
Q37246492Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy
Q34029240Altered expression of miR-21, miR-125b, and miR-203 indicates a role for these microRNAs in oral lichen planus
Q38469837An angiogenic inhibitor, cyclic RGDfV, attenuates MPTP-induced dopamine neuron toxicity.
Q34422665An easily accessible sulfated saccharide mimetic inhibits in vitro human tumor cell adhesion and angiogenesis of vascular endothelial cells
Q38458724Analysis of the intricate relationship between chronic inflammation and cancer.
Q38089191Antagonists of TNF action: clinical experience and new developments
Q39634513Anti-angiogenic activity of Ipomoea obscura extract and Ipobscurine-A.
Q38982847Anti-inflammatory activity and molecular mechanism of Oolong tea theasinensin
Q38904826Anti-inflammatory activity and molecular mechanism of delphinidin 3-sambubioside, a Hibiscus anthocyanin
Q48315476Anti-inflammatory activity of 3β-hydroxycholest-5-en-7-one isolated from Hippocampus trimaculatus leach via inhibiting iNOS, TNF-α, and 1L-1β of LPS induced RAW 264.7 macrophage cells.
Q34309920Apc-Mutant Kyoto Apc Delta (KAD) Rats Are Susceptible to 4-NQO-Induced Tongue Carcinogenesis
Q37935658BCG response prediction with cytokine gene variants and bladder cancer: where we are?
Q55073149Blood DNA methylation, nevi number, and the risk of melanoma.
Q38410101Breaking the 'harmony' of TNF-α signaling for cancer treatment
Q41873851CBP501 suppresses macrophage induced cancer stem cell like features and metastases
Q36725058CCR7 mediates the TNF-α-induced lymphatic metastasis of gallbladder cancer through the "ERK1/2 - AP-1" and "JNK - AP-1" pathways
Q39036378Cancer and inflammation
Q37546194Cannabinoid receptor ligands as potential anticancer agents--high hopes for new therapies?
Q36130505Cellular and molecular immunology of lung cancer: therapeutic implications.
Q41920583Chloroquine differentially modulates inflammatory cytokine expression in RAW 264.7 cells in response to inactivated Staphylococcus aureus.
Q33742692Circulating blood levels of IL-6, IFN-γ, and IL-10 as potential diagnostic biomarkers in gastric cancer: a controlled study
Q38193090Classical and Paradoxical Effects of TNF-α on Bone Homeostasis
Q33703030Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML.
Q42458633Colorectal cancer chemoprevention by 2 beta-cyclodextrin inclusion compounds of auraptene and 4'-geranyloxyferulic acid.
Q35190025Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity
Q93013641Correlation of TNF-α and TGF-β polymorphisms with protein levels in pancreatic ductal adenocarcinoma and colorectal cancer
Q58483427Cytokine Networks and Cancer Stem Cells
Q37152508Cytokines and Prognostic Factors in Epithelial Ovarian Cancer
Q33755625Different role of tumor necrosis factor-α polymorphism in non-Hodgkin lymphomas among Caucasian and Asian populations: a meta-analysis
Q39799084Differential expression of a novel gene BRE (TNFRSF1A modulator/BRCC45) in response to stress and biological signals.
Q49656814Differential expression profile of CXCR3 splicing variants is associated with thyroid neoplasia. Potential role in papillary thyroid carcinoma oncogenesis?
Q88963825Distant Relations: Macrophage Functions in the Metastatic Niche
Q36128919Effect of tumour necrosis factor-alpha on estrogen metabolic pathways in breast cancer cells.
Q43102640Effects of Tumor Necrosis Factor-α on Morphology and Mechanical Properties of HCT116 Human Colon Cancer Cells Investigated by Atomic Force Microscopy
Q42314594Elevated AEG-1 expression in macrophages promotes hypopharyngeal cancer invasion through the STAT3-MMP-9 signaling pathway
Q90113144Elevated Levels of TNF-α and Decreased Levels of CD68-Positive Macrophages in Primary Tumor Tissues Are Unfavorable for the Survival of Patients With Nasopharyngeal Carcinoma
Q43760187Elevated Th22 cells and related cytokines in patients with epithelial ovarian cancer
Q91815071Endothelial Cell Activation in an Embolic Ischemia-Reperfusion Injury Microfluidic Model
Q39528113Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles
Q91727199Evidence That Calebin A, a Component of Curcuma Longa Suppresses NF-B Mediated Proliferation, Invasion and Metastasis of Human Colorectal Cancer Induced by TNF-β (Lymphotoxin)
Q92988098Fangchinoline, a Bisbenzylisoquinoline Alkaloid can Modulate Cytokine-Impelled Apoptosis via the Dual Regulation of NF-κB and AP-1 Pathways
Q30409893Fullerol nanoparticles suppress inflammatory response and adipogenesis of vertebral bone marrow stromal cells--a potential novel treatment for intervertebral disc degeneration
Q35777730Gene Variants in Predicting BCG Response to Urinary Bladder Cancer
Q39922720Gene clustering analysis in human osseous remodeling
Q49987475Genomic Destabilization Triggered by Replication Stress during Senescence.
Q26991848Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey
Q37376164IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα
Q42722761ICAM-1: role in inflammation and in the regulation of vascular permeability
Q38719578Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy.
Q34993957Immunohistochemical staining of tumor necrosis factor-α and interleukin-10 in benign and malignant ovarian neoplasms.
Q41905175Impact of aging in cancer immunotherapy: The importance of using accurate preclinical models
Q90722007In Vitro Anti-Inflammatory and Immunomodulatory Activities of an Extract from the Roots of Bupleurum rotundifolium
Q37404770In Vitro TNF-α Inhibitory Activity of Brazilian Plants and Anti-Inflammatory Effect of Stryphnodendron adstringens in an Acute Arthritis Model.
Q30372024Incorporation of membrane-anchored flagellin into influenza virus-like particles enhances the breadth of immune responses.
Q36316684Increased tumor necrosis factor receptor 1 expression in human colorectal adenomas
Q37725907Inflammation, tumor necrosis factor and Wnt promotion in gastric cancer development
Q37989394Inflammatory bone loss: pathogenesis and therapeutic intervention
Q39784222Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer
Q38855698Interaction between microRNA-181a and TNFAIP1 regulates pancreatic cancer proliferation and migration
Q46407243Interleukin-8 and Tumor Necrosis Factor Predict Acute Kidney Injury After Pediatric Cardiac Surgery
Q39026662Involvement of CDX2 in the cross talk between TNF-α and Wnt signaling pathway in the colon cancer cell line Caco-2.
Q30986955Involvement of tumor necrosis factor-alpha in the upregulation of CXCR4 expression in gastric cancer induced by Helicobacter pylori
Q40727621LPS-mediated septic shock is augmented in ceramide synthase 2 null mice due to elevated activity of TNFα-converting enzyme.
Q52709051Leptin Function and Regulation.
Q55096107MDM2 Overexpression Modulates the Angiogenesis-Related Gene Expression Profile of Prostate Cancer Cells.
Q35041234Macrophage-derived tumor necrosis factor-alpha is an early component of the molecular cascade leading to angiogenesis in response to aortic injury
Q27022929Mechanisms linking excess adiposity and carcinogenesis promotion
Q35809076Mechanistic Effects of Calcitriol in Cancer Biology
Q38237985Metastasis review: from bench to bedside
Q37605958Mitogen activated protein kinases: a role in inflammatory bowel disease?
Q55364968Multifaceted Roles for Macrophages in Prostate Cancer Skeletal Metastasis.
Q37943405Multifaceted link between cancer and inflammation
Q33854606NF-κB-modulated miR-130a targets TNF-α in cervical cancer cells
Q31066313Network Biomarkers of Bladder Cancer Based on a Genome-Wide Genetic and Epigenetic Network Derived from Next-Generation Sequencing Data
Q37455689Neuroprotective and antiinflammatory properties of a novel demethylated curcuminoid.
Q24631725Occlusion regulates epidermal cytokine production and inhibits scar formation
Q35996867Oral lichen planus as a preneoplastic inflammatory model
Q38112125Origins of injection-site sarcomas in cats: the possible role of chronic inflammation-a review
Q49693459Oxaliplatin and infliximab synergize to induce regression of colon cancer.
Q36433070Phytochemicals of Aristolochia tagala and Curcuma caesia exert anticancer effect by tumor necrosis factor-α-mediated decrease in nuclear factor kappaB binding activity
Q42700802Postoperative course and prognostic value of circulating angiogenic cytokines after pancreatic cancer resection
Q54414113Prevention of Colitis-Associated Carcinogenesis with Infliximab
Q28076161Pro-Tumoral Inflammatory Myeloid Cells as Emerging Therapeutic Targets
Q90194974Proanthocyanidin-Rich Fractions from Red Rice Extract Enhance TNF-α-Induced Cell Death and Suppress Invasion of Human Lung Adenocarcinoma Cell A549
Q92480097Proinflammatory cytokine TNFα promotes HPV-associated oral carcinogenesis by increasing cancer stemness
Q33547651Proteomic analysis of osteogenic sarcoma: association of tumour necrosis factor with poor prognosis
Q38298517Regulation of angiogenesis by aminoacyl-tRNA synthetases
Q39547498Regulatory mechanisms of interleukin-8 production induced by tumour necrosis factor-α in human hepatocellular carcinoma cells
Q34093990Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats
Q90009252Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells
Q92793755Reverse Cardio-Oncology: Cancer Development in Patients With Cardiovascular Disease
Q37358114Rheumatoid arthritis: Disease or syndrome?
Q33873620Risk of incident or recurrent malignancies among patients with rheumatoid arthritis exposed to biologic therapy in the German biologics register RABBIT.
Q64389423Role of RNF20 in cancer development and progression - a comprehensive review
Q38676214Role of distinct CD4(+) T helper subset in pathogenesis of oral lichen planus
Q36413709SIRT1 in B[a]P-induced lung tumorigenesis
Q36532342Significance of TNF-α and the Adhesion Molecules: L-Selectin and VCAM-1 in Papillary Thyroid Carcinoma
Q30388015Singing modulates mood, stress, cortisol, cytokine and neuropeptide activity in cancer patients and carers.
Q37086204Spaceflight effects on T lymphocyte distribution, function and gene expression
Q38578898Stimulating immune responses to fight cancer: Basic biology and mechanisms
Q39714603Studies of phosphoproteomic changes induced by nucleophosmin-anaplastic lymphoma kinase (ALK) highlight deregulation of tumor necrosis factor (TNF)/Fas/TNF-related apoptosis-induced ligand signaling pathway in ALK-positive anaplastic large cell lymp
Q33967033Studies on the role of acid sphingomyelinase and ceramide in the regulation of tumor necrosis factor alpha (TNFalpha)-converting enzyme activity and TNFalpha secretion in macrophages
Q55074144TNF Receptor 2 Makes Tumor Necrosis Factor a Friend of Tumors.
Q38241605TNF receptors: signaling pathways and contribution to renal dysfunction
Q35159634TNF transactivation of EGFR stimulates cytoprotective COX-2 expression in gastrointestinal epithelial cells
Q88868526TNF-R2 in tumor microenvironment as prognostic factor in epithelial ovarian cancer
Q33619488TNF-TNFR2/p75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells
Q35963258TNF-alpha promotes lymphangiogenesis and lymphatic metastasis of gallbladder cancer through the ERK1/2/AP-1/VEGF-D pathway
Q37678189TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion
Q52317261TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer.
Q37370810TNF-α augments CXCR2 and CXCR3 to promote progression of renal cell carcinoma
Q89532091TNF-α increases breast cancer stem-like cells through up-regulating TAZ expression via the non-canonical NF-κB pathway
Q36439592TNF-α up-regulates protein level and cell surface expression of the leptin receptor by stimulating its export via a PKC-dependent mechanism
Q35967378TNFAIP8: a new effector for Galpha(i) coupling to reduce cell death and induce cell transformation.
Q39326301TNFα enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells
Q42363836The EspF N-Terminal of Enterohemorrhagic Escherichia coli O157:H7 EDL933w Imparts Stronger Toxicity Effects on HT-29 Cells than the C-Terminal
Q92409056The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection
Q50039906The Prediction Value of the Systemic Inflammation Score for Oral Cavity Squamous Cell Carcinoma.
Q36131712The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses.
Q64116341The efficacy of Ankaferd Blood Stopper ® in an experimental Asherman syndrome model created in rats
Q98943926The efficacy of etanercept as anti-breast cancer treatment is attenuated by residing macrophages
Q34667865The multifaceted role of curcumin in cancer prevention and treatment.
Q64235998The role of NF-κB and Elk-1 in the regulation of mouse ADAM17 expression
Q38098411The role of ceramide-1-phosphate in biological functions
Q28386593To NFκB or not to NFκB: The Dilemma on How to Inhibit a Cancer Cell Fate Regulator
Q64274457Transcriptional Analysis of Immunohistochemically Defined Subgroups of Non-Muscle-Invasive Papillary High-Grade Upper Tract Urothelial Carcinoma
Q37696067Transcriptional control of the TNF gene
Q42433657Tumor Necrosis Factor α Regulates Endothelial Progenitor Cell Migration via CADM1 and NF-kB.
Q27007477Tumor necrosis factor receptor 2: its contribution to acute cellular rejection and clear cell renal carcinoma
Q92838836Tumor necrosis factor α promotes HEp-2 cell proliferation via toll-like receptor 4 and NF-κB signaling pathways
Q33751122Tumor necrosis factor-α decreases EC-SOD expression through DNA methylation
Q84289670Tumor necrosis factor-α enhanced fusions between oral squamous cell carcinoma cells and endothelial cells via VCAM-1/VLA-4 pathway
Q61819217Tumour necrosis factor and cancer
Q52584385Tumour necrosis factor, interferon-gamma and interleukins as predictive markers of antiprogrammed cell-death protein-1 treatment in advanced non-small cell lung cancer: a pragmatic approach in clinical practice.
Q89110155Underrated enemy - from nonalcoholic fatty liver disease to cancers of the gastrointestinal tract
Q58781970Unleashing endogenous TNF-alpha as a cancer immunotherapeutic
Q37765590Unravelling the complexity of cancer-immune system interplay
Q37887822Unresolved inflammation: 'immune tsunami' or erosion of integrity in immune-privileged and immune-responsive tissues and acute and chronic inflammatory diseases or cancer
Q39564473Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice
Q91615235Utilising network pharmacology to explore the underlying mechanism of Wumei Pill in treating pancreatic neoplasms
Q41636554VEGF Neutralization Plus CTLA-4 Blockade Alters Soluble and Cellular Factors Associated with Enhancing Lymphocyte Infiltration and Humoral Recognition in Melanoma
Q38574540YKL-40/CHI3L1 drives inflammation on the road of tumor progression
Q46527046ZnO nanoparticles and organic chemical UV-filters are equally well tolerated by human immune cells

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