Gene therapy to prevent occlusion of venous bypass grafts

scientific article published on June 2008

Gene therapy to prevent occlusion of venous bypass grafts is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1586/14779072.6.5.641
P698PubMed publication ID18510482

P50authorSeppo Ylä-HerttualaQ11893052
Shalini BhardwajQ125253455
Himadri RoyQ125255956
P2860cites workInsights into the pathogenesis of vein graft disease: lessons from intravascular ultrasoundQ24802948
Improved gene delivery to human saphenous vein cells and tissue using a peptide-modified adenoviral vectorQ24804662
Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeuticsQ28141424
Neointima formation in a restenosis model is suppressed in midkine-deficient miceQ28573235
Single perivascular delivery of mitomycin C stimulates p21 expression and inhibits neointima formation in rat arteriesQ28574053
Antisense oligonucleotides to c-fos and c-jun inhibit intimal thickening in a rat vein graft modelQ30756400
Transcription inhibition induced by modified triple helix-forming oligonucleotides: a quantitative assay for evaluation in cells.Q30979414
Development of efficient viral vectors selective for vascular smooth muscle cellsQ33197377
Cardiovascular gene therapyQ33838040
Lentiviral vectors: turning a deadly foe into a therapeutic agentQ33840989
Antithrombotic strategies in gene therapyQ34027383
Adeno-associated virus vectors for gene therapy: more pros than cons?Q34080580
Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotidesQ34138108
A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivoQ34159206
Third-generation lentivirus vectors efficiently transduce and phenotypically modify vascular cells: implications for gene therapyQ34207550
Genetic engineering of vein grafts resistant to atherosclerosisQ34339752
Local gene transfer of tissue factor pathway inhibitor regulates intimal hyperplasia in atherosclerotic arteriesQ35054188
Gene therapy for cardiovascular diseasesQ35668050
Mouse model of venous bypass graft arteriosclerosisQ35753478
Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplastyQ35766125
Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell responseQ35801091
Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flowQ35927978
Release of soluble vascular endothelial growth factor receptor-1 (sFlt-1) during coronary artery bypass surgeryQ36083083
Targeting Gbeta gamma signaling in arterial vascular smooth muscle proliferation: a novel strategy to limit restenosisQ36455617
Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasiaQ36534829
The PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) trial: study rationale, design, and baseline patient characteristics.Q51342662
Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes.Q51826453
Regulation of vein graft hyperplasia by survivin, an inhibitor of apoptosis protein.Q53659822
Accelerated reendothelialization with suppressed thrombogenic property and neointimal hyperplasia of rabbit jugular vein grafts by adenovirus-mediated gene transfer of C-type natriuretic peptide.Q54547681
Percutaneous delivery of the gax gene inhibits vessel stenosis in a rabbit model of balloon angioplastyQ57243575
Adenovirus-Mediated Gene Transfer of Placental Growth Factor to Perivascular Tissue Induces Angiogenesis via Upregulation of the Expression of Endogenous Vascular Endothelial Growth Factor-AQ57382081
Angiogenic Responses of Vascular Endothelial Growth Factors in Periadventitial TissueQ57382140
Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein graftsQ37365179
Endothelial healing in vein grafts: proliferative burst unimpaired by genetic therapy of neointimal disease.Q38290419
Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapyQ38302443
Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: the PREVENT single-centre, randomised, controlled trialQ38318751
Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivoQ38326202
Design and rationale of the PREVENT III clinical trial: edifoligide for the prevention of infrainguinal vein graft failureQ38330884
In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarctionQ38343941
Prevention of restenosis by gene therapyQ38346770
Egr-1 target genes in human endothelial cells identified by microarray analysisQ38349302
Inhibition of adhesion molecule expression on human venous endothelial cells by non-viral siRNA transfection.Q39739512
Yin Yang-1 inhibits vascular smooth muscle cell growth and intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-cyclin D1 assembly.Q40122346
Inhibition of carotis venous bypass graft disease by intraoperative nucleic acid-based therapy in rabbitsQ40289245
Antisense to transforming growth factor-beta1 messenger RNA reduces vein graft intimal hyperplasia and monocyte chemotactic protein 1.Q40429676
Vein graft neointimal hyperplasia is exacerbated by tumor necrosis factor receptor-1 signaling in graft-intrinsic cellsQ40503865
Optimization of nonviral transfection: variables influencing liposome-mediated gene transfer in proliferating vs. quiescent cells in culture and in vivo using a porcine restenosis modelQ40621359
Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vectorQ41055058
Adenovirus-mediated gene transfer of the human TIMP-1 gene inhibits smooth muscle cell migration and neointimal formation in human saphenous veinQ43526519
Nitric oxide synthase (nNOS) gene transfer modifies venous bypass graft remodeling: effects on vascular smooth muscle cell differentiation and superoxide productionQ43746937
Prevention of restenosis by a herpes simplex virus mutant capable of controlled long-term expression in vascular tissue in vivoQ43873064
Gene transfer into the carotid artery using an adventitial collar: comparison of the effectiveness of the plasmid-liposome complexes, retroviruses, pseudotyped retroviruses, and adenovirusesQ43895883
Intraluminal gene transfer of endothelial cell-nitric oxide synthase suppresses intimal hyperplasia of vein grafts in cholesterol-fed rabbit: a limited biological effect as a result of the loss of medial smooth muscle cellsQ44035492
Ultrasound-mediated delivery of TIMP-3 plasmid DNA into saphenous vein leads to increased lumen size in a porcine interposition graft modelQ44196487
Gene transfer into the liver by plasmid injection into the portal vein combined with electroporationQ44383527
Sustained inhibition of experimental neointimal hyperplasia with a genetically modified herpes simplex virusQ44452117
Adenoviral delivery of a constitutively active retinoblastoma mutant inhibits neointima formation in a human explant model for vein graft diseaseQ44623752
Vein graft arterialization causes differential activation of mitogen-activated protein kinases.Q44872730
Lipoprotein lipase locus and progression of atherosclerosis in coronary-artery bypass graftsQ45151927
Influence of ischemic injury on vein graft remodeling: role of cyclic adenosine monophosphate second messenger pathway in enhanced vein graft preservation.Q45212048
Extracellular superoxide dismutase with vaccinia virus anti-inflammatory protein 35K or tissue inhibitor of metalloproteinase-1: Combination gene therapy in the treatment of vein graft stenosis in rabbitsQ45417776
Hemagglutinating virus of Japan-liposome-mediated gene transfer of endothelial cell nitric oxide synthase inhibits intimal hyperplasia of canine vein grafts under conditions of poor runoffQ45757820
Anti-MCP-1 gene therapy inhibits vascular smooth muscle cells proliferation and attenuates vein graft thickening both in vitro and in vivoQ45859529
Application to vascular adventitia of a nonviral vector for TIMP-1 gene therapy to prevent intimal hyperplasiaQ45861097
Targeting endogenous platelet-derived growth factor B-chain by adenovirus-mediated gene transfer potently inhibits in vivo smooth muscle proliferation after arterial injuryQ45861484
Controlled release of small interfering RNA targeting midkine attenuates intimal hyperplasia in vein graftsQ45862185
Enhanced inhibition of neointimal hyperplasia by genetically engineered endothelial progenitor cellsQ45874341
Antimonocyte chemoattractant protein-1 gene therapy attenuates graft vasculopathyQ45876899
Analysis of cell-specific promoters for viral gene therapy targeted at the vascular endotheliumQ45878726
Non-viral in vivo thrombomodulin gene transfer prevents early loss of thromboresistance of grafted veinsQ45879217
p27-p16 fusion gene inhibits angioplasty-induced neointimal hyperplasia and coronary artery occlusionQ45879229
Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanismQ45881879
Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease.Q45997933
Morphologic findings in saphenous veins used as coronary arterial bypass conduits for longer than 1 year: necropsy analysis of 53 patients, 123 saphenous veins, and 1865 five-millimeter segments of veinsQ46078703
VEGF-A, VEGF-D and VEGF-D(DeltaNDeltaC) induced intimal hyperplasia in carotid arteriesQ46790044
Accelerated arteriosclerosis of vein grafts in inducible NO synthase(-/-) mice is related to decreased endothelial progenitor cell repairQ46872632
Overexpression of p53 increases lumen size and blocks neointima formation in porcine interposition vein graftsQ47420905
Gene transfer to vein graft wall by HVJ-liposome method: time course and localization of gene expression.Q50522324
Antagonism of platelet-derived growth factor by perivascular gene transfer attenuates adventitial cell migration after vascular injury: new tricks for old dogs?Q50726031
P433issue5
P921main subjectgene therapyQ213901
P304page(s)641-652
P577publication date2008-06-01
P1433published inExpert Review of Cardiovascular TherapyQ15733727
P1476titleGene therapy to prevent occlusion of venous bypass grafts
P478volume6

Reverse relations

cites work (P2860)
Q45365539Adenovirus-Mediated Gene Transfer of microRNA-21 Sponge Inhibits Neointimal Hyperplasia in Rat Vein Grafts
Q35260617Development of viral vectors for use in cardiovascular gene therapy
Q91951475Exosomes derived from human umbilical cord mesenchymal stem cells inhibit vein graft intimal hyperplasia and accelerate reendothelialization by enhancing endothelial function
Q38081951Gene therapy for vein graft failure
Q35174913Helper-dependent adenoviral vector achieves prolonged, stable expression of interleukin-10 in rabbit carotid arteries but does not limit early atherogenesis
Q103756630MicroRNA-92a -mediated endothelial to mesenchymal transition controls vein graft neointimal lesion formation
Q41531960Preventing intimal thickening of vein grafts in vein artery bypass using STAT-3 siRNA.
Q39737214The dynamics of vein graft remodeling induced by hemodynamic forces: a mathematical model
Q36335468Vinpocetine suppresses pathological vascular remodeling by inhibiting vascular smooth muscle cell proliferation and migration

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