Ethanol facilitates glutamatergic transmission to dopamine neurons in the ventral tegmental area

scientific article published on 02 July 2008

Ethanol facilitates glutamatergic transmission to dopamine neurons in the ventral tegmental area is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NPP.2008.99
P8608Fatcat IDrelease_lweowfpc2rdoti46h54esdmecy
P932PMC publication ID2676579
P698PubMed publication ID18596684
P5875ResearchGate publication ID5256034

P50authorM. Foster OliveQ73275972
P2093author name stringJiang-Hong Ye
William C Griffin
Cheng Xiao
Kresimir Krnjević
Ke-Yong Li
Chunyi Zhou
Xuesi Max Shao
P2860cites workTwo types of neurone in the rat ventral tegmental area and their synaptic inputsQ24531393
D1 receptors modulate glutamate transmission in the ventral tegmental areaQ28294227
Involvement of 5-HT1B receptors within the ventral tegmental area in ethanol-induced increases in mesolimbic dopaminergic transmissionQ28582453
Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitroQ29040030
Mechanisms Underlying Differential D1 versus D2 Dopamine Receptor Regulation of Inhibition in Prefrontal CortexQ29395088
Afferent modulation of dopamine neuron firing patternsQ33801734
Cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking.Q34423187
Differential autoreceptor control of somatodendritic and axon terminal dopamine release in substantia nigra, ventral tegmental area, and striatumQ34432376
Hyperpolarization-activated cation current (Ih) is an ethanol target in midbrain dopamine neurons of miceQ34582883
Allelic association of human dopamine D2 receptor gene in alcoholismQ34998499
N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerabilityQ35153745
The tipsy terminal: presynaptic effects of ethanolQ36166542
Ethanol dually modulates GABAergic synaptic transmission onto dopaminergic neurons in ventral tegmental area: role of mu-opioid receptorsQ36713890
Efficient measurement of endogenous neurotransmitters in small localized regions of central nervous systems in vitro with HPLCQ36740461
Neuronal localization and modulation of the D2 dopamine receptor mRNA in brain of normal mice and mice lesioned with 6-hydroxydopamineQ38333578
Effects of moderate alcohol consumption on the central nervous systemQ40844399
Pharmacology and regulation of the neuronal dopamine transporterQ41460319
Properties and plasticity of excitatory synapses on dopaminergic and GABAergic cells in the ventral tegmental area.Q41650647
Adaptive responses of gamma-aminobutyric acid neurons in the ventral tegmental area to chronic ethanolQ41702995
Microdialysis in the mouse nucleus accumbens: a method for detection of monoamine and amino acid neurotransmitters with simultaneous assessment of locomotor activity.Q41725152
Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine.Q42164271
Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental areaQ42453485
Effects of ethanol on extracellular amino acid levels in high-and low-alcohol sensitive rats: a microdialysis studyQ73230260
Presynaptic dopamine D2-like receptors inhibit excitatory transmission onto rat ventral tegmental dopaminergic neuronesQ73445715
Ethanol inhibition of N-methyl-D-aspartate responses involves presynaptic gamma-aminobutyric acid(B) receptorsQ74016667
Ethanol selectively inhibits enhanced vesicular release at excitatory synapses: real-time visualization in intact hippocampal slicesQ42456192
Presynaptic D1 dopamine receptors facilitate glutamatergic neurotransmission in the rat globus pallidus.Q42518579
Effect of ethanol on extracellular 5-HT and glutamate in the nucleus accumbens and prefrontal cortex: comparison between the Lewis and Fischer 344 rat strainsQ42521016
Plasmalemmal mu-opioid receptor distribution mainly in nondopaminergic neurons in the rat ventral tegmental areaQ43700720
Additive effect of stress and drug cues on reinstatement of ethanol seeking: exacerbation by history of dependence and role of concurrent activation of corticotropin-releasing factor and opioid mechanisms.Q44132559
Effects of ethanol on midbrain neurons: role of opioid receptorsQ44335433
κ-Opioid Agonists Directly Inhibit Midbrain Dopaminergic NeuronsQ44343360
Metabotropic glutamate and muscarinic cholinergic receptor-mediated preferential inhibition of N-methyl-D-aspartate component of transmissions in rat ventral tegmental areaQ44345598
Both kappa and mu opioid agonists inhibit glutamatergic input to ventral tegmental area neuronsQ44347621
Protein kinase A regulates regulates inhibition of N- and P/Q-type calcium channels by ethanol in PC12 cells.Q44592271
Dopamine activity in the nucleus accumbens during consummatory phases of oral ethanol self-administrationQ44628784
Endocannabinoids mediate presynaptic inhibition of glutamatergic transmission in rat ventral tegmental area dopamine neurons through activation of CB1 receptors.Q44723162
Intracranial self-administration of ethanol within the ventral tegmental area of male Wistar rats: evidence for involvement of dopamine neurons.Q44755323
Acute and chronic ethanol alter glutamatergic transmission in rat central amygdala: an in vitro and in vivo analysis.Q44770118
Neuroscience of addictionQ44880443
Ethanol suppression of ventral tegmental area GABA neuron electrical transmission involves N-methyl-D-aspartate receptorsQ44915343
Multiple mechanisms underlie burst firing in rat midbrain dopamine neurons in vitroQ45015087
Presynaptic glycine receptors on GABAergic terminals facilitate discharge of dopaminergic neurons in ventral tegmental area.Q45105996
The dopamine D1 antagonist reduces ethanol reward for C57BL/6 miceQ45152841
The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons?Q46076764
Effect of operant self-administration of 10% ethanol plus 10% sucrose on dopamine and ethanol concentrations in the nucleus accumbensQ46526751
Developmentally regulated actions of alcohol on hippocampal glutamatergic transmission.Q46681399
Ethanol inhibits glutamatergic neurotransmission in nucleus accumbens neurons by multiple mechanisms.Q46853928
Pharmacological reduction of small conductance calcium-activated potassium current (SK) potentiates the excitatory effect of ethanol on ventral tegmental area dopamine neurons.Q48178103
Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanolQ48292663
Involvement of non-NMDA glutamate receptors in central amygdala in synaptic actions of ethanol and ethanol-induced reward behavior.Q48313896
Blocking GABA(A) receptors in the anterior ventral tegmental area attenuates ethanol intake of the alcohol-preferring P rat.Q48377993
Effect of dopamine agonists and antagonists on ethanol-reinforced behavior: the involvement of the nucleus accumbens.Q48387758
Low doses of ethanol activate dopaminergic neurons in the ventral tegmental areaQ48435230
Patch-clamp studies in the CNS illustrate a simple new method for obtaining viable neurons in rat brain slices: glycerol replacement of NaCl protects CNS neuronsQ48471281
Dopamine receptor regulation of Ca2+ levels in individual isolated nerve terminals from rat striatum: comparison of presynaptic D1-like and D2-like receptorsQ48485522
Alcohol self-administration: further examination of the role of dopamine receptors in the nucleus accumbens.Q48623545
6-OHDA-lesions of the nucleus accumbens disrupt the acquisition but not the maintenance of ethanol consumption in the alcohol-preferring P line of ratsQ48623584
Disruption of dopamine D1 receptor gene expression attenuates alcohol-seeking behaviorQ48714883
Spontaneous bursting activity of dopaminergic neurons in midbrain slices from immature rats: role of N-methyl-D-aspartate receptorsQ48740378
A comparison of axonal and somatodendritic dopamine release using in vivo dialysisQ48784598
Serotonin-3 receptor and ethanol-stimulated somatodendritic dopamine releaseQ48873657
Autoregulation and monoamine interactions in the ventral tegmental area in the absence and presence of cocaine: a microdialysis study in freely moving rats.Q51617574
Ethanol directly excites dopaminergic ventral tegmental area reward neurons.Q52172659
Amphetamine depresses excitatory synaptic transmission via serotonin receptors in the ventral tegmental area.Q52277642
Ethanol decreases glutamatergic synaptic transmission in rat nucleus accumbens in vitro: naloxone reversal.Q54231433
Quantification of Ethanol Concentrations in the Extracellular Fluid of the Rat BrainQ62081277
A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniquesQ68053421
5-hydroxytryptamine1B receptors block the GABAB synaptic potential in rat dopamine neuronsQ68112683
Two cell types in rat substantia nigra zona compacta distinguished by membrane properties and the actions of dopamine and opioidsQ69581473
Increased probability of GABA release during withdrawal from morphineQ71955013
The effects of 6-hydroxydopamine lesions of the nucleus accumbens and the mesolimbic dopamine system on oral self-administration of ethanol in the ratQ72558093
Dopamine receptor agonist reduces ethanol self-administration in the ethanol-preferring C57BL/6J inbred mouseQ72643330
Expression of D1 receptor mRNA in projections from the forebrain to the ventral tegmental areaQ73042969
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectdopamineQ170304
gbr-12935Q5512952
P304page(s)307-318
P577publication date2008-07-02
P1433published inNeuropsychopharmacologyQ2261280
P1476titleEthanol facilitates glutamatergic transmission to dopamine neurons in the ventral tegmental area
P478volume34

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cites work (P2860)
Q47901530Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits.
Q92266705Comparison between baclofen and topiramate in alcohol dependence: A prospective study
Q48034026Convergent Neuronal Plasticity and Metaplasticity Mechanisms of Stress, Nicotine, and Alcohol
Q30517934Decreased sensitivity of NMDA receptors on dopaminergic neurons from the posterior ventral tegmental area following chronic nondependent alcohol consumption
Q41145672Differential Effects of Toluene and Ethanol on Dopaminergic Neurons of the Ventral Tegmental Area.
Q39289210Effects of acute alcohol on excitability in the CNS.
Q36650320Effects of alcohol on the membrane excitability and synaptic transmission of medium spiny neurons in the nucleus accumbens
Q61805027Electrical Abnormalities in Dopaminergic Neurons of the Substantia Nigra in Mice With an Aromatic L-Amino Acid Decarboxylase Deficiency
Q60949890Ethanol Modulates Glutamatergic Transmission and NMDAR-Mediated Synaptic Plasticity in the Agranular Insular Cortex
Q27687624Ethanol action on dopaminergic neurons in the ventral tegmental area: interaction with intrinsic ion channels and neurotransmitter inputs
Q51739075Ethanol actions on the ventral tegmental area: novel potential targets on reward pathway neurons.
Q57467644Ethanol acts on KCNK13 potassium channels in the ventral tegmental area to increase firing rate and modulate binge-like drinking
Q35048012Ethanol affects network activity in cultured rat hippocampus: mediation by potassium channels
Q33998572Ethanol blocks long-term potentiation of GABAergic synapses in the ventral tegmental area involving mu-opioid receptors
Q46731814Ethanol drives aversive conditioning through dopamine 1 receptor and glutamate receptor-mediated activation of lateral habenula neurons
Q42090722Ethanol enhances glutamate transmission by retrograde dopamine signaling in a postsynaptic neuron/synaptic bouton preparation from the ventral tegmental area
Q36067436Ethanol increases glutamate neurotransmission in the posterior ventral tegmental area of female wistar rats
Q35146203Ethanol modulation of synaptic plasticity
Q36218971Ethanol produces corticotropin-releasing factor receptor-dependent enhancement of spontaneous glutamatergic transmission in the mouse central amygdala
Q48564064Ethanol, glutamate, and the ventral tegmental area--a commentary on: Ding, Engleman, Rodd, and McBride, "ethanol increases glutamate neurotransmission in the posterior ventral tegmental area of female wistar rats".
Q30367006Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings.
Q36398915Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.
Q34847679Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons
Q35847720GABAergic actions mediate opposite ethanol effects on dopaminergic neurons in the anterior and posterior ventral tegmental area
Q35699323GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol.
Q35532015Glutamatergic and nonglutamatergic neurons of the ventral tegmental area establish local synaptic contacts with dopaminergic and nondopaminergic neurons
Q35994557Identifying the role of pre-and postsynaptic GABA(B) receptors in behavior
Q26997102Illicit dopamine transients: reconciling actions of abused drugs
Q101496558Influence of nicotine and alcohol on sleep and implications on insomnia: the reward-attention circuit model
Q91637181Inhibition of Morphine- and Ethanol-Mediated Stimulation of Mesolimbic Dopamine Neurons by Withania somnifera
Q48725498Involvement of nucleus accumbens dopamine D1 receptors in ethanol drinking, ethanol-induced conditioned place preference, and ethanol-induced psychomotor sensitization in mice
Q34716755Involvement of the orexin/hypocretin system in ethanol conditioned place preference
Q36850576Levetiracetam has opposite effects on alcohol- and cocaine-related behaviors in C57BL/6J mice
Q36900651Locus coeruleus neuronal activity determines proclivity to consume alcohol in a selectively-bred line of rats that readily consumes alcohol
Q30588578Modeling dopaminergic and other processes involved in learning from reward prediction error: contributions from an individual differences perspective
Q52315696Neurobiology of Propofol Addiction and Supportive Evidence: What Is the New Development?
Q36165252Neurochemical and neurostructural plasticity in alcoholism
Q34342747Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence
Q36137598Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions
Q37128659Nicotine decreases ethanol-induced dopamine signaling and increases self-administration via stress hormones
Q37346923Nicotinic acetylcholine receptors containing the α6 subunit contribute to ethanol activation of ventral tegmental area dopaminergic neurons
Q35142884Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus
Q96953338One Is Not Enough: Understanding and Modeling Polysubstance Use
Q36277604Perspective: Translational studies on glutamate and dopamine neurocircuitry in addictions: implications for addiction treatment.
Q33880993Phasic dopamine release in appetitive behaviors and drug addiction
Q38139358Possible contributions of a novel form of synaptic plasticity in Aplysia to reward, memory, and their dysfunctions in mammalian brain
Q34359231Potential substrates for nicotine and alcohol interactions: a focus on the mesocorticolimbic dopamine system
Q45995140Preclinical development of moxidectin as a novel therapeutic for alcohol use disorder.
Q47331113Presynaptic Ethanol Actions: Potential Roles in Ethanol Seeking
Q34916526Previous ethanol experience enhances synaptic plasticity of NMDA receptors in the ventral tegmental area
Q33557667Propofol facilitates glutamatergic transmission to neurons of the ventrolateral preoptic nucleus
Q37600399RGS6 as a Novel Therapeutic Target in CNS Diseases and Cancer.
Q35129073Regulator of G protein signaling 6 is a critical mediator of both reward-related behavioral and pathological responses to alcohol
Q35892651Repeated exposure of the posterior ventral tegmental area to nicotine increases the sensitivity of local dopamine neurons to the stimulating effects of ethanol
Q36342934Rodent models and mechanisms of voluntary binge-like ethanol consumption: Examples, opportunities, and strategies for preclinical research
Q57476791Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence
Q35915923SKF-83566, a D1-dopamine receptor antagonist, inhibits the dopamine transporter
Q34270933Salsolinol facilitates glutamatergic transmission to dopamine neurons in the posterior ventral tegmental area of rats
Q36871836Salsolinol modulation of dopamine neurons
Q36061588Spontaneous transmitter release is critical for the induction of long-term and intermediate-term facilitation in Aplysia
Q33746834Stroke triggers nigrostriatal plasticity and increases alcohol consumption in rats.
Q30388351Synaptic effects induced by alcohol
Q88599123The Cerebellar GABAAR System as a Potential Target for Treating Alcohol Use Disorder
Q33845389Treatment of alcohol dependence with low-dose topiramate: an open-label controlled study
Q41967906Viral-mediated knockdown of mGluR7 in the nucleus accumbens mediates excessive alcohol drinking and increased ethanol-elicited conditioned place preference in rats
Q37030212αCaMKII autophosphorylation controls the establishment of alcohol drinking behavior

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