Intraperitoneal delivery of human natural killer cells for treatment of ovarian cancer in a mouse xenograft model.

scientific article published on October 2013

Intraperitoneal delivery of human natural killer cells for treatment of ovarian cancer in a mouse xenograft model. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.JCYT.2013.05.022
P932PMC publication ID3775496
P698PubMed publication ID23993303
P5875ResearchGate publication ID256329964

P50authorJeffrey S. MillerQ42399944
Dan S KaufmanQ56332545
P2093author name stringValarie McCullar
Melissa A Geller
David A Knorr
Laura Bendzick
Lee Pribyl
David A Hermanson
P2860cites workInterleukin-21 activates human natural killer cells and modulates their surface receptor expressionQ24300519
Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cellsQ27309991
A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosisQ28270998
Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancerQ29619483
Bioluminescent imaging demonstrates that transplanted human embryonic stem cell-derived CD34(+) cells preferentially develop into endothelial cellsQ33801849
Memory-like responses of natural killer cellsQ34007381
Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activityQ34016504
CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset.Q34310907
Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cellsQ34600272
Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cellsQ34605718
TGF-β Blockade Controls Ascites by Preventing Abnormalization of Lymphatic Vessels in Orthotopic Human Ovarian Carcinoma ModelsQ34694524
Relapsed ovarian cancer: challenges and management strategies for a chronic diseaseQ34905674
Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaquesQ35001598
NK cells and immune "memory"Q35539280
Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicityQ35909663
The role of regulatory T cells in the control of natural killer cells: relevance during tumor progressionQ36652214
Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15Q36666195
Prospects for the use of NK cells in immunotherapy of human cancer.Q36793616
IL-15 trans-presentation promotes human NK cell development and differentiation in vivoQ37061837
Cytokine-induced memory-like natural killer cellsQ37100910
A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancerQ37141237
Natural killer cell-based immunotherapy in cancer: current insights and future prospectsQ37554765
Use of allogeneic NK cells for cancer immunotherapy.Q37957140
Establishment, Characterization, and Successful Adaptive Therapy against Human Tumors of NKG Cell, a New Human NK Cell LineQ39525496
The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancerQ39556474
IL-2 Costimulation Enables Statin-Mediated Activation of Human NK Cells, Preferentially through a Mechanism Involving CD56+ Dendritic CellsQ39643965
CD56 negative NK cells: origin, function, and role in chronic viral diseaseQ56953283
DNAX Accessory Molecule-1 Mediated Recognition of Freshly Isolated Ovarian Carcinoma by Resting Natural Killer CellsQ57226771
IL-2−driven Regulation of NK Cell Receptors With Regard to the Distribution of CD16+ and CD16− Subpopulations and In Vivo Influence After Haploidentical NK Cell InfusionQ63386780
Preoperative detection of peripherally circulating cancer cells and its prognostic significance in ovarian cancerQ79253356
P433issue10
P921main subjectovarian cancerQ172341
xenograftQ64148587
P304page(s)1297-1306
P577publication date2013-10-01
P1433published inCytotherapyQ5201399
P1476titleIntraperitoneal delivery of human natural killer cells for treatment of ovarian cancer in a mouse xenograft model
P478volume15

Reverse relations

cites work (P2860)
Q36916476Anti-ovarian tumor response of donor peripheral blood mononuclear cells is due to infiltrating cytotoxic NK cells
Q94315837CXCR1 Expression to Improve Anti-Cancer Efficacy of Intravenously Injected CAR-NK Cells in Mice with Peritoneal Xenografts
Q91786100Cellular Therapies for the Treatment of Hematological Malignancies; Swine Are an Ideal Preclinical Model
Q91115863Cytokine-induced memory-like natural killer cells have enhanced function, proliferation, and in vivo expansion against ovarian cancer cells
Q90224747EGFR-Specific Tyrosine Kinase Inhibitor Modifies NK Cell-Mediated Antitumoral Activity against Ovarian Cancer Cells
Q58788761Early Investigations and Recent Advances in Intraperitoneal Immunotherapy for Peritoneal Metastasis
Q41812231Ex Vivo Expanded Human NK Cells Survive and Proliferate in Humanized Mice with Autologous Human Immune Cells
Q47752280Ex vivo-expanded NK cells from blood and ascites of ovarian cancer patients are cytotoxic against autologous primary ovarian cancer cells.
Q91736879Harnessing natural killer cells for the treatment of ovarian cancer
Q38714915IL-15 super-agonist (ALT-803) enhances natural killer (NK) cell function against ovarian cancer
Q36463830Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer
Q39005211Intraperitoneal immunotherapy: historical perspectives and modern therapy
Q39239278Modeling Natural Killer Cell Targeted Immunotherapies.
Q46677873Mouse Xenograft Model for Intraperitoneal Administration of NK Cell Immunotherapy for Ovarian Cancer
Q38941698NK cells with KIR2DS2 immunogenotype have a functional activation advantage to efficiently kill glioblastoma and prolong animal survival.
Q33749684OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues
Q38857163Oxaliplatin regulates expression of stress ligands in ovarian cancer cells and modulates their susceptibility to natural killer cell-mediated cytotoxicity.
Q58129516PD-L1 blockade enhances anti-tumor efficacy of NK cells
Q58582595Peritoneal NK cells are responsive to IL-15 and percentages are correlated with outcome in advanced ovarian cancer patients
Q35623804Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer
Q94402935SCID pigs: An emerging large animal NK model
Q35185573Secreted β3-integrin enhances natural killer cell activity against acute myeloid leukemia cells
Q47113878Sestrin2 and sestrin3 suppress NK-92 cell-mediated cytotoxic activity on ovarian cancer cells through AMPK and mTORC1 signaling
Q41337940Umbilical cord blood CD34+ progenitor-derived NK cells efficiently kill ovarian cancer spheroids and intraperitoneal tumors in NOD/SCID/IL2Rgnull mice.
Q88506528Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses

Search more.