Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial

scientific article published on 14 April 2009

Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1012611530
P356DOI10.1186/1475-2875-8-63
P932PMC publication ID2678145
P698PubMed publication ID19366448
P5875ResearchGate publication ID24277599

P50authorOgobara K. DoumboQ3349810
Stephen RulisaQ53086508
Issaka SagaraQ72250521
Hamma MaigaQ72250613
Alassane DickoQ72250716
Niawanlou DaraQ114402286
Kourane SissokoQ125294545
Abdoulaye A. DjimdeQ28913759
Wilfred Fomban MbachamQ44156522
Ishag AdamQ47149235
P2093author name stringF Herwig Jansen
Oumar B Traore
Yahia T Dicko
P2860cites workMalariaQ55878749
Comparison of different artemisinin-based combinations for the treatment of Plasmodium falciparum malaria in children in Kigali, Rwanda, an area of resistance to sulfadoxine-pyrimethamine: artesunate plus sulfadoxine/pyrimethamine versus artesunateQ81542344
The global distribution of clinical episodes of Plasmodium falciparum malariaQ24599466
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trialQ28469217
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Artesunate and dihydroartemisinin (DHA): unusual decomposition products formed under mild conditions and comments on the fitness of DHA as an antimalarial drugQ31121606
The economic burden of malaria.Q34292910
A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern SudanQ35017456
Artemether-lumefantrine for uncomplicated malaria: a systematic reviewQ35709551
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A comparative study on the efficacy of artesunate plus sulphadoxine/pyrimethamine versus artemether-lumefantrine in eastern SudanQ35925276
Adding artesunate to sulphadoxine-pyrimethamine greatly improves the treatment efficacy in children with uncomplicated falciparum malaria on the coast of Benin, West AfricaQ36465190
Therapeutic efficacy of sulfadoxine-pyrimethamine, amodiaquine and the sulfadoxine-pyrimethamine-amodiaquine combination against uncomplicated Plasmodium falciparum malaria in young children in Cameroon.Q36937442
Chemical instability determines the biological action of the artemisininsQ37066126
Artesunate and sulfadoxine-pyrimethamine combinations for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda: a randomized, double-blind, placebo-controlled trialQ38881940
The efficacy of antimalarial monotherapies, sulphadoxine–pyrimethamine and amodiaquine in East Africa: implications for sub‐regional policyQ38882717
Randomised trial of artesunate and mefloquine alone and in sequence for acute uncomplicated falciparum malariaQ39188623
A randomized, placebo-controlled, double-blind trial on sulfadoxine-pyrimethamine alone or combined with artesunate or amodiaquine in uncomplicated malariaQ39257146
Efficacy of chloroquine and sulfadoxine/pyrimethamine mono- and combined therapy against falciparum malaria in Sudan.Q40448284
Efficacy and safety of artemether-lumefantrine (Coartem) tablets (six-dose regimen) in African infants and children with acute, uncomplicated falciparum malariaQ40510491
Molecular diagnosis of resistance to antimalarial drugs during epidemics and in war zonesQ41913694
Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria.Q41914794
Assessment of the relative advantage of various artesunate-based combination therapies by a multi-treatment Bayesian random-effects meta-analysis.Q41941734
The efficacy of sulfadoxine-pyrimethamine alone and in combination with chloroquine for malaria treatment in rural Eastern Sudan: the interrelation between resistance, age and gametocytogenesisQ41945474
Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children: a randomised, multicentre trialQ43972330
Single-day, three-dose treatment with fixed dose combination artesunate/sulfamethoxypyrazine/pyrimethamine to cure Plasmodium falciparum malariaQ46152786
A randomized trial of artesunate-mefloquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali.Q46266769
Molecular epidemiology of malaria in Cameroon. XXVII. Clinical and parasitological response to sulfadoxine-pyrimethamine treatment and Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase alleles in Cameroonian childrenQ47838452
A randomized trial of artesunate-sulfamethoxypyrazine-pyrimethamine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Mali.Q48036406
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P921main subjectmalariaQ12156
Plasmodium falciparumQ311383
pyrimethamineQ421072
artesunateQ707939
lumefantrineQ904464
P304page(s)63
P577publication date2009-04-14
P1433published inMalaria JournalQ15749954
P1476titleEfficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial
P478volume8

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