Acylated cholesteryl galactosides are specific antigens of borrelia causing lyme disease and frequently induce antibodies in late stages of disease

scientific article published on 23 March 2009

Acylated cholesteryl galactosides are specific antigens of borrelia causing lyme disease and frequently induce antibodies in late stages of disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M809575200
P932PMC publication ID2679432
P698PubMed publication ID19307181

P50authorVolker FingerleQ40340105
P2093author name stringUlf B Göbel
Nicolas W J Schröder
Ralf R Schumann
Ulrich Zähringer
Bettina Wilske
Gunthard Stübs
P2860cites workGenomic sequence of a Lyme disease spirochaete, Borrelia burgdorferiQ22122357
The emergence of Lyme diseaseQ22241895
Lyme disease-a tick-borne spirochetosis?Q22242252
The Lyme vaccine: a cautionary taleQ22251377
A newly discovered cholesteryl galactoside from Borrelia burgdorferiQ24670017
Cloning and functional expression of UGT genes encoding sterol glucosyltransferases from Saccharomyces cerevisiae, Candida albicans, Pichia pastoris, and Dictyostelium discoideumQ27936426
Clinical characteristics and treatment outcome of early Lyme disease in patients with microbiologically confirmed erythema migransQ28207826
Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. Lyme Disease Vaccine Study GroupQ28277088
Structural analysis of glycolipids from Borrelia burgdorferiQ30704109
Acylated cholesteryl galactoside as a novel immunogenic motif in Borrelia burgdorferi sensu strictoQ30804250
Epidemiological aspects and molecular characterization of Borrelia burgdorferi s.l. from southern Germany with special respect to the new species Borrelia spielmanii sp. nov.Q31117930
Improvement of Lyme borreliosis serodiagnosis by a newly developed recombinant immunoglobulin G (IgG) and IgM line immunoblot assay and addition of VlsE and DbpA homologuesQ34041878
Blotting of glycolipids and phospholipids from a high-performance thin-layer chromatogram to a polyvinylidene difluoride membraneQ34315118
Lipid metabolism of Borrelia hermsiQ34433570
Laboratory testing for Lyme disease: possibilities and practicalitiesQ34515948
Microbiological and serological diagnosis of Lyme borreliosisQ34608068
Sterols and acylated proteins in mycoplasmasQ34610860
Lyme disease--United States, 2003-2005.Q34637392
Characterization of outer membranes isolated from Borrelia burgdorferi, the Lyme disease spirocheteQ35415911
Fatty acids of Treponema pallidum and Borrelia burgdorferi lipoproteinsQ36106623
Biosynthesis of Cholesteryl Glucoside by Mycoplasma gallinarumQ36774165
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteriaQ38466705
Impact of strain heterogeneity on Lyme disease serology in Europe: comparison of enzyme-linked immunosorbent assays using different species of Borrelia burgdorferi sensu latoQ39552310
Unique cholesteryl glucosides in Helicobacter pylori: composition and structural analysisQ39838352
Lipid profile of Helicobacter spp.: presence of cholesteryl glucoside as a characteristic featureQ39840895
Lipids of the Spirochaetales: comparison of the lipids of several members of the genera Spirochaeta, Treponema, and LeptospiraQ40090914
Immunological and molecular variability of OspA and OspC. Implications for Borrelia vaccine developmentQ41063389
Distribution of Borrelia burgdorferi sensu lato genomic groups in Europe, a reviewQ41708845
Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritisQ47762137
Monogalactosyl diglyceride: A new neurolipidQ51208674
Functional analysis of a lipid galactosyltransferase synthesizing the major envelope lipid in the Lyme disease spirochete Borrelia burgdorferi.Q54442581
A 14,000 MW lipoprotein and a glycolipid-like structure of Borrelia burgdorferi induce proliferation and immunoglobulin production in mouse B cells at high frequencies.Q54631211
Cholesterol glucosylation promotes immune evasion by Helicobacter pyloriQ56984433
The Presenting Manifestations of Lyme Disease and the Outcomes of TreatmentQ59759433
The clinical evolution of Lyme arthritisQ69415294
Incidence of Lyme borreliosis in the Würzburg region of GermanyQ73235432
Lyme borreliosisQ94329194
P433issue20
P407language of work or nameEnglishQ1860
P921main subjectLyme diseaseQ201989
antibodyQ79460
cholesteryl 6-O-oleoyl-beta-D-galactosideQ27131219
cholesteryl 6-O-oleoyl-beta-D-glucosideQ27132059
P304page(s)13326-13334
P577publication date2009-03-23
P1433published inJournal of Biological ChemistryQ867727
P1476titleAcylated cholesteryl galactosides are specific antigens of borrelia causing lyme disease and frequently induce antibodies in late stages of disease
P478volume284

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cites work (P2860)
Q36250228A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease
Q59135908A bite so sweet: the glycobiology interface of tick-host-pathogen interactions
Q47651704Analysis of Lipids and Lipid Rafts in Borrelia
Q35174495Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2009-2010.
Q37217348Borrelia burgdorferi HtrA: evidence for twofold proteolysis of outer membrane protein p66.
Q92259111CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells
Q38768859Cholesterol lipids and cholesterol-containing lipid rafts in bacteria
Q34443882Cholesterol lipids of Borrelia burgdorferi form lipid rafts and are required for the bactericidal activity of a complement-independent antibody.
Q36658958Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.
Q36000800Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi
Q37836082Hijacking and Use of Host Lipids by Intracellular Pathogens
Q33598636Human complement regulators C4b-binding protein and C1 esterase inhibitor interact with a novel outer surface protein of Borrelia recurrentis
Q35567134Hypercholesterolemia and ApoE deficiency result in severe infection with Lyme disease and relapsing-fever Borrelia
Q38039373Immunological functions of steryl glycosides
Q28484938Lipid exchange between Borrelia burgdorferi and host cells
Q56764150Lyme borreliosis
Q46596183Ordered Membrane Domain-Forming Properties of the Lipids of Borrelia burgdorferi
Q37883972Prevention of lyme disease: promising research or sisyphean task?
Q34733566Proving lipid rafts exist: membrane domains in the prokaryote Borrelia burgdorferi have the same properties as eukaryotic lipid rafts
Q38503879Raft-like membrane domains in pathogenic microorganisms.
Q37634449Selective association of outer surface lipoproteins with the lipid rafts of Borrelia burgdorferi
Q55363430Simple glycolipids of microbes: Chemistry, biological activity and metabolic engineering.
Q37156619Statins reduce spirochetal burden and modulate immune responses in the C3H/HeN mouse model of Lyme disease.
Q35099146Synthesis and antigenicity of BBGL-2 glycolipids of Borrelia burgdorferi, the causative agent of Lyme disease.
Q30152732The TamB ortholog of Borrelia burgdorferi interacts with the β-barrel assembly machine (BAM) complex protein BamA
Q38406434The lipid raft proteome of Borrelia burgdorferi
Q27690233Using Sterol Substitution to Probe the Role of Membrane Domains in Membrane Functions