Loss of calcineurin in the spinal dorsal horn contributes to neuropathic pain, and intrathecal administration of the phosphatase provides prolonged analgesia

scientific article published on 15 June 2013

Loss of calcineurin in the spinal dorsal horn contributes to neuropathic pain, and intrathecal administration of the phosphatase provides prolonged analgesia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.PAIN.2013.06.019
P932PMC publication ID3778136
P698PubMed publication ID23778296

P2093author name stringGordana Miletic
Vjekoslav Miletic
Jennifer A Lippitt
Kristine M Sullivan
P2860cites workSynaptic plasticity: multiple forms, functions, and mechanismsQ28242702
A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1Q28568896
Loose ligation of the rat sciatic nerve elicits early accumulation of Shank1 protein in the post-synaptic density of spinal dorsal horn neuronsQ28574014
Ethical guidelines for investigations of experimental pain in conscious animalsQ29617510
Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal cord in addition to pain behaviorQ33814688
Calcineurin and synaptophysin in the human spinal cord of normal individuals and patients with familial dysautonomiaQ34188899
A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.Q34554719
Cocaine regulates MEF2 to control synaptic and behavioral plasticityQ34818266
Changes in calcineurin message, enzyme activity and protein content in the spinal dorsal horn are associated with chronic constriction injury of the rat sciatic nerveQ35076046
Calcineurin regulation of neuronal plasticityQ35586583
Synaptic plasticity and phosphorylationQ36564122
Scaffolding proteins at the postsynaptic density: shank as the architectural frameworkQ37168233
Models and mechanisms of hyperalgesia and allodyniaQ37431137
Calcineurin as a nociceptor modulator.Q37577347
Central mechanisms of pathological painQ37800357
Reversible blockade of experience-dependent plasticity by calcineurin in mouse visual cortex.Q46478231
Neurotrophin activation of NFAT-dependent transcription contributes to the regulation of pro-nociceptive genesQ48174754
Unilateral vestibular deafferentation-induced changes in calcium signaling-related molecules in the rat vestibular nuclear complexQ48286771
Calcineurin contributes to spatial memory impairment induced by rapid eye movement sleep deprivationQ48394713
Localization of the calcium/calmodulin-dependent protein phosphatase, calcineurin, in the hindbrain and spinal cord of the rat.Q48864692
Control of the establishment of aversive memory by calcineurin and Zif268.Q50794842
Positive and negative regulatory mechanisms that mediate long-term memory storageQ74747032
Increases in the phosphorylation of cyclic AMP response element binding protein (CREB) and decreases in the content of calcineurin accompany thermal hyperalgesia following chronic constriction injury in ratsQ78446733
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectneuropathic painQ2798704
P304page(s)2024-2033
P577publication date2013-06-15
P1433published inPainQ2317902
P1476titleLoss of calcineurin in the spinal dorsal horn contributes to neuropathic pain, and intrathecal administration of the phosphatase provides prolonged analgesia
P478volume154

Reverse relations

cites work (P2860)
Q40490343Calcineurin Dysregulation Underlies Spinal Cord Injury-Induced K+ Channel Dysfunction in DRG Neurons.
Q45369250Calcineurin inhibitor induces pain hypersensitivity by potentiating pre- and postsynaptic NMDA receptor activity in spinal cords
Q36299923Protein kinase C gamma-mediated phosphorylation of GluA1 in the postsynaptic density of spinal dorsal horn neurons accompanies neuropathic pain, and dephosphorylation by calcineurin is associated with prolonged analgesia
Q37115203Ulinastatin attenuates neuropathic pain induced by L5-VRT via the calcineurin/IL-10 pathway.

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