HIV-1 antiretrovirals induce oxidant injury and increase intima-media thickness in an atherogenic mouse model

scientific article published on 09 March 2009

HIV-1 antiretrovirals induce oxidant injury and increase intima-media thickness in an atherogenic mouse model is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TOXLET.2009.02.017
P932PMC publication ID2680796
P698PubMed publication ID19429260
P5875ResearchGate publication ID24414927

P2093author name stringBo Jiang
Tammy R Dugas
Karen Y Stokes
Alok R Khandelwal
Valeria Y Hebert
P2860cites workPharmacological basis for concentration-controlled therapy with zidovudine, lamivudine, and indinavirQ28345258
A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.Q29035699
Genetic control of inflammatory gene induction and NF-kappa B-like transcription factor activation in response to an atherogenic diet in miceQ35610718
Quantification of isoprostanes as indices of oxidant stress and the risk of atherosclerosis in humansQ35980355
Platelet-associated NAD(P)H oxidase contributes to the thrombogenic phenotype induced by hypercholesterolemiaQ35989704
Highly active antiretroviral therapy-associated metabolic syndrome and cardiovascular riskQ36468854
Effects of pravastatin on lipoproteins and endothelial function in patients receiving human immunodeficiency virus protease inhibitorsQ40518202
Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993.Q40882910
Endothelial dysfunction in atherosclerosis.Q41221374
Premature atherosclerosis in HIV-infected individuals--focus on protease inhibitor therapyQ43556074
A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitorsQ43613003
One-step solid-phase extraction procedure for F(2)-isoprostanes.Q43654415
Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunctionQ43678570
Assessment of atherosclerosis using carotid ultrasonography in a cohort of HIV-positive patients treated with protease inhibitorsQ43723992
Trends in the prescription of antiretroviral drugs and impact on plasma HIV-RNA measurementsQ43754392
Antiretrovirals induce direct endothelial dysfunction in vivo.Q44083807
Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression.Q44552097
Pharmacokinetics of indinavir/ritonavir (800/100 mg) in combination with efavirenz (600 mg) in HIV-1-infected subjectsQ44606717
Risk of metabolic abnormalities in patients infected with HIV receiving antiretroviral therapy that contains lopinavir-ritonavirQ44807945
Mitochondrial oxidative stress in human hepatoma cells exposed to stavudineQ45003754
Effects of HIV drug combinations on endothelin-1 and vascular cell proliferation.Q45061915
Direct effects of nucleoside reverse transcriptase inhibitors on rat cardiac mitochondrial bioenergeticsQ46667580
Simultaneous determination of 16 anti-HIV drugs in human plasma by high-performance liquid chromatographyQ46890085
Colour-Doppler ultrasonography of carotid vessels in patients treated with antiretroviral therapy: a comparative study.Q53897720
Premature lesions of the carotid vessels in HIV-1-infected patients treated with protease inhibitors.Q54066253
Red and black rice decrease atherosclerotic plaque formation and increase antioxidant status in rabbits.Q55034793
Protease inhibitors and cardiovascular outcomes in patients with HIV-1Q57955538
Mouse Models of AtherosclerosisQ64357718
HIV antiretroviral drug combination induces endothelial mitochondrial dysfunction and reactive oxygen species production, but not apoptosisQ64377031
Plasma lipid transfer proteinsQ68884684
Variation in susceptibility to atherosclerosis among inbred strains of miceQ69805944
A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart AssociationQ72415283
Deficiency of inflammatory cell adhesion molecules protects against atherosclerosis in miceQ73707721
Cardiomyopathy, nucleoside reverse transcriptase inhibitors and mitochondria are linked through AIDS and its therapyQ81110657
P433issue3
P921main subjectatherosclerosisQ12252367
anti-retroviral agentQ50430310
P304page(s)164-171
P577publication date2009-03-09
P1433published inToxicology LettersQ1796854
P1476titleHIV-1 antiretrovirals induce oxidant injury and increase intima-media thickness in an atherogenic mouse model
P478volume187

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cites work (P2860)
Q30430542Antiretrovirals induce endothelial dysfunction via an oxidant-dependent pathway and promote neointimal hyperplasia
Q36104280Brain injury caused by HIV protease inhibitors: role of lipodystrophy and insulin resistance.
Q33901061Development of a novel self-microemulsifying drug delivery system for reducing HIV protease inhibitor-induced intestinal epithelial barrier dysfunction
Q43258132Management of hypertriglyceridaemia caused by combination antiretroviral therapy in HIV-infected patients: role of omega-3 polyunsaturated fatty acids at different dosages, compared with fibrates
Q34349192Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice
Q36701580Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones
Q46130631Nucleoside/nucleotide reverse transcriptase inhibitors attenuate angiogenesis and lymphangiogenesis by impairing receptor tyrosine kinases signalling in endothelial cells
Q35556516Overexpression of mitochondrial antioxidant manganese superoxide dismutase (MnSOD) provides protection against AZT- or 3TC-induced endothelial dysfunction.
Q37155953Sex differences in urinary biomarkers of vascular and endothelial function in HIV-infected persons receiving antiretroviral therapy
Q59353210Viral infection and atherosclerosis

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