Prospectively validated dosing nomograms for maximizing the pharmacodynamics of vancomycin administered by continuous infusion in critically ill patients

scientific article published on 17 February 2009

Prospectively validated dosing nomograms for maximizing the pharmacodynamics of vancomycin administered by continuous infusion in critically ill patients is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.01149-08
P932PMC publication ID2681515
P698PubMed publication ID19223642

P50authorFederico PeaQ38544304
Francesco CristiniQ104757072
Pierluigi VialeQ113862183
Mario FurlanutQ115867398
Federica PavanQ115867399
P2093author name stringMassimo Crapis
Camilla Negri
P2860cites workGuidelines for the Management of Adults with Hospital-acquired, Ventilator-associated, and Healthcare-associated PneumoniaQ22241905
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008Q24644984
Prediction of creatinine clearance from serum creatinineQ29615603
Continuous versus intermittent infusion of vancomycin in severe Staphylococcal infections: prospective multicenter randomized studyQ33982863
Vancomycin in vitro bactericidal activity and its relationship to efficacy in clearance of methicillin-resistant Staphylococcus aureus bacteremiaQ35879117
Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variabilityQ36263480
The pharmacokinetic and pharmacodynamic properties of vancomycinQ36328971
Potential impact of vancomycin pulmonary distribution on treatment outcomes in patients with methicillin-resistant Staphylococcus aureus pneumoniaQ36428418
Larger vancomycin doses (at least four grams per day) are associated with an increased incidence of nephrotoxicityQ36538707
Pharmacodynamics of antibiotics to treat multidrug-resistant Gram-positive hospital infectionsQ36777850
Relationship between vancomycin MIC and failure among patients with methicillin-resistant Staphylococcus aureus bacteremia treated with vancomycinQ36870858
Better outcomes through continuous infusion of time-dependent antibiotics to critically ill patients?Q37211603
Are glycopeptides still appropriate and convenient for empiric use?Q37333194
In vitro studies of pharmacodynamic properties of vancomycin against Staphylococcus aureus and Staphylococcus epidermidisQ39559251
Clinical pharmacokinetics of vancomycinQ39743278
TDM coupled with Bayesian forecasting should be considered an invaluable tool for optimizing vancomycin daily exposure in unstable critically ill patientsQ40621864
Increased vancomycin MICs for Staphylococcus aureus clinical isolates from a university hospital during a 5-year periodQ41066970
Methicillin-resistant Staphylococcus aureus prolongs intensive care unit stay in ventilator-associated pneumonia, despite initially appropriate antibiotic therapyQ43905496
Clinical relevance of increasing glycopeptide MICs against Staphylococcus aureusQ44755051
Risk factors for nephrotoxicity associated with continuous vancomycin infusion in outpatient parenteral antibiotic therapyQ45107382
Pharmacodynamics of vancomycin and other antimicrobials in patients with Staphylococcus aureus lower respiratory tract infectionsQ45127594
Assessment of renal function in recently admitted critically ill patients with normal serum creatinineQ45258125
High-dose vancomycin therapy for methicillin-resistant Staphylococcus aureus infections: efficacy and toxicityQ45302930
Vancomycin MICs did not creep in Staphylococcus aureus isolates from 2002 to 2006 in a setting with low vancomycin usageQ46541443
Continuous-infusion vancomycin therapy for preterm neonates with suspected or documented Gram-positive infections: a new dosage schedule.Q46616448
Vancomycin minimum inhibitory concentration as a predictor of mortality in methicillin-resistant Staphylococcus aureus bacteremia: a second lookQ46639389
Pneumonia caused by oxacillin-resistant Staphylococcus aureus treated with glycopeptidesQ46691587
Should the currently recommended twice-daily dosing still be considered the most appropriate regimen for treating MRSA ventilator-associated pneumonia with vancomycin?Q46728126
Influence of vancomycin minimum inhibitory concentration on the treatment of methicillin-resistant Staphylococcus aureus bacteremiaQ46826194
Monitoring of vancomycin serum levels for the treatment of staphylococcal infectionsQ46929797
Effects of prolonged vancomycin administration on methicillin-resistant Staphylococcus aureus (MRSA) in a patient with recurrent bacteraemiaQ46933141
Replacement of 24-h creatinine clearance by 2-h creatinine clearance in intensive care unit patients: a single-center study.Q51911200
Point: Vancomycin is not obsolete for the treatment of infection caused by methicillin-resistant Staphylococcus aureusQ80363319
Counterpoint: Vancomycin and Staphylococcus aureus--an antibiotic enters obsolescenceQ80363323
Vancomycin MIC creep in non-vancomycin-intermediate Staphylococcus aureus (VISA), vancomycin-susceptible clinical methicillin-resistant S. aureus (MRSA) blood isolates from 2001-05Q80595494
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectpatientQ181600
pharmacodynamicsQ725307
vancomycinQ424027
P304page(s)1863-1867
P577publication date2009-02-17
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleProspectively validated dosing nomograms for maximizing the pharmacodynamics of vancomycin administered by continuous infusion in critically ill patients
P478volume53

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