Tissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficits

scientific article published on 28 October 2008

Tissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficits is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BRAINRES.2008.10.035
P932PMC publication ID2683391
P698PubMed publication ID19007756
P5875ResearchGate publication ID23472140

P2093author name stringGuohua Xi
Richard F Keep
Ya Hua
Masanobu Okauchi
P2860cites workCystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminaseQ24548047
Differential expression of multiple transglutaminases in human brain. Increased expression and cross-linking by transglutaminases 1 and 2 in Alzheimer's diseaseQ28145899
Progression of mass effect after intracerebral hemorrhageQ28198134
Evidence for apoptosis after intercerebral hemorrhage in rat striatumQ28577314
Transglutaminase 2 induces nuclear factor-kappaB activation via a novel pathway in BV-2 microgliaQ28582000
Cystamine inhibits transglutaminase and caspase-3 cleavage in glutamate-exposed astroglial cellsQ31160300
Tissue transglutaminase: a possible role in neurodegenerative diseasesQ33881855
Gene regulation and DNA damage in the ageing human brainQ34326236
Type 2 transglutaminase and cell death.Q36061280
Mechanisms of brain injury after intracerebral haemorrhage.Q36345249
Transglutaminase 2 in inflammationQ36486713
Experimental intracerebral hemorrhage: relationship between brain edema, blood flow, and blood-brain barrier permeability in ratsQ36752639
Mutant huntingtin protein: a substrate for transglutaminase 1, 2, and 3.Q40457537
Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stressQ40725013
Brain edema after experimental intracerebral hemorrhage: role of hemoglobin degradation productsQ42170839
Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in ratsQ42464660
Intracerebral hemorrhage-induced neuronal deathQ42503455
Tissue-transglutaminase in rat and human brain: light and electron immunocytochemical analysis and in situ hybridization studyQ43806434
Protein crosslinking, tissue transglutaminase, alternative splicing and neurodegenerationQ43819036
Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamineQ43873037
Injury-induced "switch" from GTP-regulated to novel GTP-independent isoform of tissue transglutaminase in the rat spinal cordQ44028734
Cystamine inhibits caspase activity. Implications for the treatment of polyglutamine disordersQ44233701
Increased expression of tissue-type transglutaminase following middle cerebral artery occlusion in ratsQ44899092
Transglutaminase activity and transglutaminase mRNA transcripts in gerbil brain ischemiaQ44917306
Cerebral PET imaging and histological evidence of transglutaminase inhibitor cystamine induced neuroprotection in transgenic R6/2 mouse model of Huntington's diseaseQ45296331
The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminaseQ45296905
Treatment of YAC128 mice and their wild-type littermates with cystamine does not lead to its accumulation in plasma or brain: implications for the treatment of Huntington diseaseQ45297332
Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease.Q45298533
Estrogen therapy for experimental intracerebral hemorrhage in ratsQ46668717
Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trialQ47622762
Experimental intracerebral mass: description of model, intracranial pressure changes and neuropathologyQ48104900
Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioningQ48194280
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.Q48455875
Protective effect against 17beta-estradiol on neuronal apoptosis in hippocampus tissue following transient ischemia/recirculation in mongolian gerbils via down-regulation of tissue transglutaminase activityQ48460483
Oxidative brain injury from extravasated erythrocytes after intracerebral hemorrhageQ48466283
Behavioral tests after intracerebral hemorrhage in the rat.Q48475050
Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.Q48537185
Tissue transglutaminase overexpression in the brain potentiates calcium-induced hippocampal damageQ48617707
Quantitative analysis of injured, necrotic, and apoptotic cells in a new experimental model of intracerebral hemorrhageQ49030403
Up-regulation of tissue-type transglutaminase after traumatic brain injuryQ58115382
Apoptosis as a Form of Cell Death in Intracerebral HemorrhageQ73280625
Transglutaminase-catalyzed protein cross-linking in the molecular program of apoptosis and its relationship to neuronal processesQ77757582
P407language of work or nameEnglishQ1860
P304page(s)229-236
P577publication date2008-10-28
P1433published inBrain ResearchQ4955782
P1476titleTissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficits
P478volume1249

Reverse relations

cites work (P2860)
Q48445336Cystamine improves functional recovery via axon remodeling and neuroprotection after stroke in mice
Q33912442Cystamine protects from 3-nitropropionic acid lesioning via induction of nf-e2 related factor 2 mediated transcription
Q37809948Exploring Neuroprotective Drug Therapies for Intracerebral Hemorrhage
Q35801721Inhibition of carbonic anhydrase reduces brain injury after intracerebral hemorrhage
Q36106030Iron enhances the neurotoxicity of amyloid β.
Q41038343Jugular Venous Reflux Is Associated with Perihematomal Edema after Intracerebral Hemorrhage
Q42493460Microglia Activation and Polarization After Intracerebral Hemorrhage in Mice: the Role of Protease-Activated Receptor-1.
Q37967368Recent advances in the development of tissue transglutaminase (TG2) inhibitors
Q33525390Reference genes for normalising gene expression data in collagenase-induced rat intracerebral haemorrhage
Q36877739Susceptibility to intracerebral hemorrhage-induced brain injury segregates with low aerobic capacity in rats.
Q36241237Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation
Q26824549Transglutaminase is a therapeutic target for oxidative stress, excitotoxicity and stroke: a new epigenetic kid on the CNS block
Q53262522Treatment of intracerebral hemorrhage in animal models: meta-analysis.

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