Chromosome 1q gain and tenascin-C expression are candidate markers to define different risk groups in pediatric posterior fossa ependymoma

scientific article published on 22 August 2016

Chromosome 1q gain and tenascin-C expression are candidate markers to define different risk groups in pediatric posterior fossa ependymoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S40478-016-0349-9
P932PMC publication ID4994287
P698PubMed publication ID27550150

P50authorPeter F AmbrosQ41883260
Christian DorferQ48238806
Monika ChocholousQ57421981
P2093author name stringIrene Slavc
Johannes Gojo
Karin Dieckmann
Christine Haberler
Asuka Araki
Harald Heinzl
Thomas Czech
Inge M Ambros
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Ki-67 immunolabeling index is an accurate predictor of outcome in patients with intracranial ependymomaQ31084569
C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymomaQ33730977
Gain of 1q and loss of 22 are the most common changes detected by comparative genomic hybridisation in paediatric ependymomaQ34085362
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Identification of gains on 1q and epidermal growth factor receptor overexpression as independent prognostic markers in intracranial ependymomaQ34512893
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Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age GroupsQ36461766
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Histological predictors of outcome in ependymoma are dependent on anatomic site within the central nervous systemQ39459076
Copy number gain of 1q25 predicts poor progression-free survival for pediatric intracranial ependymomas and enables patient risk stratification: a prospective European clinical trial cohort analysis on behalf of the Children's Cancer Leukaemia GroupQ39652042
Pediatric intracranial ependymoma: the roles of surgery, radiation and chemotherapyQ39719582
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EZH2 expression is a prognostic factor in childhood intracranial ependymoma: a Canadian Pediatric Brain Tumor Consortium studyQ42175070
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Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C.Q44958621
The extracellular matrix glycoprotein Tenascin-C is expressed by oligodendrocyte precursor cells and required for the regulation of maturation rate, survival and responsiveness to platelet-derived growth factorQ45153218
Incidence patterns for ependymoma: a surveillance, epidemiology, and end results study.Q45944762
Molecular staging of intracranial ependymoma in children and adultsQ46526605
Primary postoperative chemotherapy without radiotherapy for intracranial ependymoma in children: the UKCCSG/SIOP prospective studyQ48099096
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FISH-based detection of 1p 19q codeletion in oligodendroglial tumors: procedures and protocols for neuropathological practice – a publication under the auspices of the Research Committee of the European Confederation of Neuropathological Societies (Q53627617
Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-κB signaling pathway.Q55461138
FISH-based detection of 1p 19q codeletion in oligodendroglial tumors: procedures and protocols for neuropathological practice - a publication under the auspices of the Research Committee of the European Confederation of Neuropathological Societies (Q55463396
Distribution of the extracellular matrix glycoproteins in ependymomas--an immunohistochemical study with follow-up analysis.Q55472062
Prognostic factors in intracranial ependymomas in children.Q55475092
Immunohistochemical markers for intracranial ependymoma recurrence. An analysis of 88 cases.Q55475232
P433issue1
P921main subjectependymomaQ1346753
pediatric ependymomaQ7159224
P304page(s)88
P577publication date2016-08-22
P1433published inActa Neuropathologica CommunicationsQ27724912
P1476titleChromosome 1q gain and tenascin-C expression are candidate markers to define different risk groups in pediatric posterior fossa ependymoma
P478volume4

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Q90085893An integrated molecular profile of endometrioid ovarian cancer
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Q38858546Telomerase activation in posterior fossa group A ependymomas is associated with dismal prognosis and chromosome 1q gain
Q64053923Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease

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