| scholarly article | Q13442814 |
| P50 | author | Meenhard Herlyn | Q16732421 |
| Matt Guerra | Q125342113 | ||
| Ronan McDaid | Q125342127 | ||
| P2093 | author name string | John Lee | |
| Ling Li | |||
| Hong Yu | |||
| David E Elder | |||
| Xiaowei Xu | |||
| Rachel Hammond | |||
| Phyllis Gimotty | |||
| Katharine L Nathanson | |||
| Maria Dalla Palma | |||
| Patricia Possik | |||
| Patricia Van Belle | |||
| Suresh M Kumar | |||
| P2860 | cites work | Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling | Q22003910 |
| Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 | ||
| 1-Mb resolution array-based comparative genomic hybridization using a BAC clone set optimized for cancer gene analysis | Q24629750 | ||
| Mutations of the BRAF gene in human cancer | Q27860760 | ||
| Summaries of Affymetrix GeneChip probe level data | Q27860888 | ||
| Histone H2A variants H2AX and H2AZ | Q28207014 | ||
| Principles of tumor suppression | Q28240740 | ||
| The transcriptional targets of p53 in apoptosis control | Q28248026 | ||
| Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints | Q29617405 | ||
| Transcriptional control of human p53-regulated genes | Q29617650 | ||
| Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication | Q29617915 | ||
| BRAFE600-associated senescence-like cell cycle arrest of human naevi | Q29619550 | ||
| p53: an overview of over two decades of study. | Q30160032 | ||
| Inactivation of the apoptosis effector Apaf-1 in malignant melanoma | Q31984891 | ||
| Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression | Q34084509 | ||
| High frequency of BRAF mutations in nevi | Q34160519 | ||
| Use of human tissue to assess the oncogenic activity of melanoma-associated mutations | Q34716087 | ||
| The RB and p53 pathways in cancer | Q34804764 | ||
| Apoptosis and melanoma: molecular mechanisms | Q35063945 | ||
| Isolation of a novel population of multipotent adult stem cells from human hair follicles | Q35088428 | ||
| p53 downstream targets and chemosensitivity. | Q35116655 | ||
| Senescence of human fibroblasts induced by oncogenic Raf. | Q35210205 | ||
| The melanocyte differentiation program predisposes to metastasis after neoplastic transformation | Q35216430 | ||
| A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors | Q35649378 | ||
| Recent advances in melanoma biology | Q35718944 | ||
| Basic fibroblast growth factor and ultraviolet B transform melanocytes in human skin | Q35746395 | ||
| Transcriptional regulation by p53: one protein, many possibilities | Q36436698 | ||
| Nestin in central nervous system cells | Q37057915 | ||
| The role of p53 in pigmentation, tanning and melanoma | Q37257745 | ||
| Dual inactivation of RB and p53 pathways in RAS-induced melanomas | Q39458533 | ||
| Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. | Q40014237 | ||
| Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma | Q40149334 | ||
| Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma | Q40169723 | ||
| Deregulated Syk inhibits differentiation and induces growth factor-independent proliferation of pre-B cells. | Q40203885 | ||
| Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability. | Q40260735 | ||
| Recurrent patterns of dual RB and p53 pathway inactivation in melanoma | Q40340097 | ||
| Human melanoma cell line UV responses show independency of p53 function. | Q40963817 | ||
| Cellular senescence in naevi and immortalisation in melanoma: a role for p16? | Q42016240 | ||
| The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence. | Q42123048 | ||
| Overexpression and mutations of p53 in metastatic malignant melanomas | Q42519944 | ||
| Evaluation of Tet-on system to avoid transgene down-regulation in ex vivo gene transfer to the CNS. | Q42525849 | ||
| BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. | Q45252786 | ||
| Novel genes associated with malignant melanoma but not benign melanocytic lesions | Q46226262 | ||
| Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells | Q46395700 | ||
| Less keratinocyte-derived factors related to more keratinocyte apoptosis in depigmented than normally pigmented suction-blistered epidermis may cause passive melanocyte death in vitiligo | Q46457478 | ||
| An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells | Q47583291 | ||
| Induction of melanoma phenotypes in human skin by growth factors and ultraviolet B. | Q51052019 | ||
| Both products of the mouse Ink4a/Arf locus suppress melanoma formation in vivo. | Q53377245 | ||
| Mutation and expression of the p53 gene in malignant melanoma cell lines | Q70768852 | ||
| p53 gene mutation and expression in naevi and melanomas | Q71912241 | ||
| p53 downstream target genes and tumor suppression: a classical view in evolution | Q79306638 | ||
| Cutaneous melanomas associated with nevi | Q79367275 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2367-2377 | |
| P577 | publication date | 2009-04-23 | |
| P1433 | published in | The American Journal of Pathology | Q4744259 |
| P1476 | title | The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes | |
| P478 | volume | 174 |
| Q36096818 | A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell lines |
| Q34494126 | Artificial skin in perspective: concepts and applications |
| Q90505011 | Assessment of clinical outcomes with immune checkpoint inhibitor therapy in melanoma patients with CDKN2A and TP53 pathogenic mutations |
| Q34251026 | BRAF Drives Synovial Fibroblast Transformation in Rheumatoid Arthritis |
| Q44268815 | BRAF exon 15 T1799A mutation is common in melanocytic nevi, but less prevalent in cutaneous malignant melanoma, in Chinese Han. |
| Q59127638 | Cancer modeling by Transgene Electroporation in Adult Zebrafish (TEAZ) |
| Q35947022 | Cellular senescence and cancer chemotherapy resistance |
| Q27022355 | Current and future trials of targeted therapies in cutaneous melanoma |
| Q36556389 | Effective intra-S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines |
| Q39104052 | Establishment and characterization of a primary and a metastatic melanoma cell line from Grey horses. |
| Q33961759 | High-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assays |
| Q36961667 | Human skin neural crest progenitor cells are susceptible to BRAF(V600E)-induced transformation |
| Q37033216 | Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways |
| Q39570667 | Interaction of mutant hepatitis B X protein with p53 tumor suppressor protein affects both transcription and cell survival |
| Q57664796 | Malignant Melanoma–a Genetic Overview |
| Q34026182 | Mechanisms of chromosomal instability in melanoma |
| Q21284811 | Melanoma: from melanocyte to genetic alterations and clinical options |
| Q36371541 | MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies |
| Q33725172 | Molecular pathogenesis of sporadic melanoma and melanoma-initiating cells |
| Q83230246 | Mutationally-activated PI3'-kinase-α promotes de-differentiation of lung tumors initiated by the BRAF oncoprotein kinase |
| Q37984547 | Narrowing the knowledge gaps for melanoma |
| Q33913135 | P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation |
| Q26766708 | Phytochemicals for the Management of Melanoma |
| Q41056748 | Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status |
| Q28237793 | Raf kinases in cancer-roles and therapeutic opportunities |
| Q38213115 | Restoring the tumour suppressive function of p53 as a parallel strategy in melanoma therapy. |
| Q42425082 | Role for IGFBP7 in senescence induction by BRAF. |
| Q33683160 | Role of senescence and mitotic catastrophe in cancer therapy |
| Q35679320 | Snail1 mediates hypoxia-induced melanoma progression |
| Q39693657 | Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study |
| Q37745182 | Targeting the MAPK pathway in melanoma: why some approaches succeed and other fail |
| Q37736262 | Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells |
| Q27010154 | The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics |
| Q34490200 | The dynamic control of signal transduction networks in cancer cells |
| Q37188584 | The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival |
| Q38124247 | The role of AKT/mTOR pathway in stress response to UV-irradiation: implication in skin carcinogenesis by regulation of apoptosis, autophagy and senescence |
| Q37931402 | The role of mitogen- and stress-activated protein kinase pathways in melanoma |
| Q35164039 | The three-dimensional human skin reconstruct model: a tool to study normal skin and melanoma progression |
| Q35591610 | Three-dimensional modeling of ovarian cancer. |
| Q82244659 | Xmrk in medaka: a new genetic melanoma model |
| Q33584237 | Zebrafish have a competent p53-dependent nucleotide excision repair pathway to resolve ultraviolet B-induced DNA damage in the skin |
| Q39654655 | p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation |
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