Toll-like receptors: lessons to learn from normal and malignant human B cells

scientific article published on 30 June 2008

Toll-like receptors: lessons to learn from normal and malignant human B cells is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1182/BLOOD-2008-02-140673
P932PMC publication ID2532798
P698PubMed publication ID18591383
P5875ResearchGate publication ID5260896

P2093author name stringCatherine Pellat-Deceunynck
Régis Bataille
Isabelle Bekeredjian-Ding
Gaëtan Jego
David Chiron
P2860cites workPlasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6Q24317429
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Pathogen recognition and innate immunityQ27861084
TLR signalingQ28291637
Immunosuppressive networks in the tumour environment and their therapeutic relevanceQ29619244
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapyQ29619961
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGEQ29620722
Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsetsQ30834266
Toll-like receptor 2-mediated human B cell differentiationQ33246383
Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunityQ34491896
The molecular classification of multiple myelomaQ34530992
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharideQ34531452
Toll-like receptors in systemic autoimmune diseaseQ34576448
IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patientsQ34657691
Respiratory tract infections and subsequent risk of chronic lymphocytic leukemiaQ35642807
Endogenous ligands of Toll-like receptorsQ35792678
Modulating vaccine responses with dendritic cells and Toll-like receptorsQ35826412
Optimizing immunotherapy in multiple myeloma: Restoring the function of patients' monocyte-derived dendritic cells by inhibiting p38 or activating MEK/ERK MAPK and neutralizing interleukin-6 in progenitor cellsQ35848756
Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphomaQ35849633
Tolerance, not immunity, crucially depends on IL-2.Q35877199
Heparan sulfate proteoglycans and heparanase--partners in osteolytic tumor growth and metastasis.Q35943349
T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cellsQ35955998
Dendritic cells control B cell growth and differentiationQ35963666
Failure of B Cells of Chronic Lymphocytic Leukemia in Presenting Soluble and AlloantigensQ61657716
Respiratory tract infections in the pathway to multiple myeloma: a population-based study in ScandinaviaQ61826842
Staphylococcus aureus Protein A Triggers T Cell-Independent B Cell Proliferation by Sensitizing B Cells for TLR2 LigandsQ63408461
Loxoribine induces chronic lymphocytic leukemia B cells to traverse the cell cycleQ72776641
Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cellsQ73386737
CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigensQ73492223
Immunostimulatory CpG-oligonucleotides induce functional high affinity IL-2 receptors on B-CLL cells: costimulation with IL-2 results in a highly immunogenic phenotypeQ73795158
A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cellsQ78863058
TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responsesQ80427941
Distinct and overlapping roles of interleukin-10 and CD25+ regulatory T cells in the inhibition of antitumor CD8 T-cell responsesQ81223194
B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotidesQ81474815
Toll-like receptors, endogenous ligands, and systemic autoimmune disease.Q36079856
Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptorsQ36151542
B cell intrinsic TLR signals amplify but are not required for humoral immunityQ36294387
Toll-like receptor agonists in the treatment of chronic lymphocytic leukemiaQ36635059
Heparanase, hyaluronan, and CD44 in cancers: a breast carcinoma perspective.Q36641814
Regulation of TLR4 signaling and the host interface with pathogens and danger: the role of RP105.Q36807091
Human Toll-like receptor-dependent induction of interferons in protective immunity to virusesQ36990637
Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunityQ36990647
Toll-like receptor 9 (TLR9) agonists in the treatment of cancerQ37050998
TLR2 - promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificityQ37136130
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotidesQ38289912
CpG stimulation of precursor B-lineage acute lymphoblastic leukemia induces a distinct change in costimulatory molecule expression and shifts allogeneic T cells toward a Th1 responseQ38332055
Immunostimulatory oligodeoxynucleotides induce apoptosis of B cell chronic lymphocytic leukemia cells.Q38333437
The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cellsQ38355683
Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics.Q40005494
TLR7 and CD40 cooperate in IL-6 production via enhanced JNK and AP-1 activation.Q40019462
Pathogen-associated molecular patterns are growth and survival factors for human myeloma cells through Toll-like receptorsQ40289625
Toll-like receptors mediate proliferation and survival of multiple myeloma cellsQ40291993
HMGB1 expression and release by bone cellsQ40328332
Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphoblastic leukaemia.Q40330092
CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10.Q40512685
Immunology: Toll-like receptors and antibody responsesQ42125203
Cutting edge: Lipopolysaccharide induces IL-10-producing regulatory CD4+ T cells that suppress the CD8+ T cell responseQ42631213
Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patientsQ42742001
Memory B cells are biased towards terminal differentiation: a strategy that may prevent repertoire freezingQ42951748
Antibody-dependent induction of type I interferons by poliovirus in human mononuclear blood cells requires the type II fcgamma receptor (CD32).Q43768979
Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines.Q43845859
Toll-like receptor-7 tolerizes malignant B cells and enhances killing by cytotoxic agentsQ43881315
Modulation of malignant B cell activation and apoptosis by bcl-2 antisense ODN and immunostimulatory CpG ODN.Q44052611
MyD88 is required for the formation of long-term humoral immunity to virus infectionQ45405612
Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN.Q46391163
Regression of lymphomatous skin deposits in a chronic lymphocytic leukemia patient treated with the Toll-like receptor-7/8 agonist, imiquimodQ46600658
Immunomodulatory effects of Toll-like receptor-7 activation on chronic lymphocytic leukemia cellsQ46845154
Overcoming immune tolerance against multiple myeloma with lentiviral calnexin-engineered dendritic cellsQ48032304
TLR9 stimulation drives naïve B cells to proliferate and to attain enhanced antigen presenting function.Q51973780
A distinct Toll-like receptor repertoire in human tonsillar B cells, directly activated by PamCSK, R-837 and CpG-2006 stimulation.Q51981691
Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response.Q51996837
Maintenance of serological memory by polyclonal activation of human memory B cells.Q52008907
The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease.Q53595110
Toll-like receptor stimulation as a third signal required for activation of human naive B cells.Q53632191
Sensitization of IL-2 signaling through TLR-7 enhances B lymphoma cell immunogenicity.Q53633872
Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway.Q55043619
Cytotoxic combination of loxoribine with fludarabine and mafosfamide on freshly isolated B-chronic lymphocytic leukemia cellsQ57012928
Control of B-cell responses by Toll-like receptorsQ59066168
FcγRIIb controls bone marrow plasma cell persistence and apoptosisQ60268649
P433issue6
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
P304page(s)2205-2213
P577publication date2008-06-30
P1433published inBloodQ885070
P1476titleToll-like receptors: lessons to learn from normal and malignant human B cells
P478volume112

Reverse relations

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